OFK Lab

The laboratory of Professor Omar F. Khan in the University of Toronto's Institute of Biomedical Engineering. Canada Research Chair in Nucleic Acid Therapeutics.

[BiotechTV @BiotechTV]

𝐁𝐫𝐢𝐠𝐡𝐭 𝐌𝐢𝐧𝐝𝐬: Meet @JanicePang_, a @UofT PhD candidate who was lead author of a much discussed paper in @scisignal about using long noncoding RNAs as future therapeutic medicines.

Full video: https://t.co/tXBmg0aj6S

[John Maraganore 🇺🇸🇬🇷🇺🇦 @JMaraganore]

Love this!

For over a decade, I’ve been infatuated with miRNAs and lncRNAs as disease targets, revealing a whole new frontier of human therapeutics.

It’s complex space, but nothing this big is ever that easy!

[OFK Lab @OFKLab]

Amazing summary, @BiotechTV !

[BiotechTV @BiotechTV]

𝐒𝐜𝐢𝐞𝐧𝐜𝐞 𝐒𝐩𝐨𝐭𝐥𝐢𝐠𝐡𝐭: A paper in @scisignal this month by researchers at the University of Toronto illustrated progress being made in turning long noncoding RNAs (lncRNAs) into medicines. Via @chloeckirk

Link to research: https://t.co/o25kwQOQBU

[Science Signaling @scisignal]

A team presents the synthesis and chemical engineering of 3 #lncRNAs to suppress inflammation in mice and in human cells—one of the first demonstrations that lncRNAs outside of cells can be deployed to affect cell biology. @OFKLab @JanicePang_ @bme_uoft https://t.co/QLeQnLoP42

[Ryan Cross the Science Boss @RLCscienceboss]

Study suggests long non-coding RNA (#lncRNA) has potential as new class of genetic medicine, including as an anti-inflammatory drug. I talked to the scientists at University of Toronto to learn more for my story in @endpts - https://t.co/0twBYbeYxB

[University of Toronto Engineering @UofTEngineering]

Mining the dark transcriptome: U of T Engineering researchers create the first potential drug molecules from long noncoding RNA 🧬 https://t.co/gYx3NT6z5S

[OFK Lab @OFKLab]

We’re excited to share our work on making new therapeutics from the dark transcriptome, published in @scisignal! Thank you to @CIHR_IRSC @NSERC_CRSNG #CRC @TIPS_SPIIE for helping us unlock an entirely new class of therapeutics!

[Science Signaling @scisignal]

A team presents the synthesis and chemical engineering of 3 #lncRNAs to suppress inflammation in mice and in human cells—one of the first demonstrations that lncRNAs outside of cells can be deployed to affect cell biology. @OFKLab @JanicePang_ @bme_uoft https://t.co/QLeQnLoP42

[Science Signaling @scisignal]

A team presents the synthesis and chemical engineering of 3 #lncRNAs to suppress inflammation in mice and in human cells—one of the first demonstrations that lncRNAs outside of cells can be deployed to affect cell biology. @OFKLab @JanicePang_ @bme_uoft https://t.co/QLeQnLoP42

[Magnetic Resonance News @nmr900]

Researchers @juliencsenecal @JagritiNatraj @OFKLab @UofTEngineering are working to enable the design of faster-degrading drug delivery systems using optimized cell-free reactions monitored by 1H NMR https://t.co/9CwAoTWnN3 #NMRnews #NMRchat #NMR 🧲

[OFK Lab @OFKLab]

Happy news: @juliencsenecal completed a stellar PhD defence, earning his OFK Lab coveralls! This amazing engineer's PhD highlights include patents, papers, a book chapter and a startup. I'm so proud! Julien, thank you for sharing these past 5 years with me and the Blue Coats 🎉

[OFK Lab @OFKLab]

@bme_uoft @UofTEngineering Thanks to my incredible mentors and students!

[Biomedical Engineering @ University of Toronto @bme_uoft]

Professor Omar F. Khan has been awarded the prestigious McCharles Prize for Early Career Research Distinction for his contributions to the fields of biomedical and immune engineering: https://t.co/r1Fifke6dV

[Biomedical Engineering @ University of Toronto @bme_uoft]

Dr. Omar Khan @OFKLab comments on the rising measles cases surge worldwide. Ensure your vaccinations are up to date, especially in BC where access to records varies: https://t.co/07dQ8YWqP7

[U of T Emerging and Pandemic Infections Consortium @UofTEPIC]

We are thrilled to announce the newest cohort of EPIC Doctoral Awards recipients! From diagnostics to virology to epidemiology, these PhD students are tackling important questions that will improve our ability to respond to infectious diseases.

Read more: https://t.co/On7kaRafwJ

[OFK Lab @OFKLab]

If you’re in Vancouver or @UBC, check out tomorrow’s @SBME_UBC seminar from Professor Khan on all things chemistry, engineering and nanoparticles! Link below!
https://t.co/n1Nk9UGp2g

[Nature Reviews Methods Primers @MethodsPrimers]

Check out this Comment from @OFKLab for best practices for characterizing RNA lipid nanoparticles

https://t.co/21JdOAyyF7

[OFK Lab @OFKLab]

Thanks @MethodsPrimers! This has already generated some great discussions with old and new colleagues! @bme_uoft @CRSNG_NSERC @CIHR_IRSC @TIPS_SPIIE @MbD_UofT @uoftengineering @UofTPRiME

[Nature Reviews Methods Primers @MethodsPrimers]

New Comment from @OFKLab! Best practices for characterizing RNA lipid nanoparticles

Adhering to 7 best practices on the collection, interpretation and reporting of characterization data will improve early-stage research and promote clinical translation.

https://t.co/21JdOAy0Pz

[Medicine by Design @MbD_UofT]

Yesterday @cos_uoft summer students, funded by #MedicinebyDesign to work in #regenmed labs at #UofT & affiliated hospitals, shared highlights from their projects. Read more about the program for high potential students from underrepresented communities: https://t.co/axpbt7ql5Z

[Janice Pang @JanicePang_]

Awesome work this summer by our undergrads Fabiha and Avery! Thank you for keeping the lab bench energized these past few months 👏🏻

[OFK Lab @OFKLab]

What happens when you merge ionizable lipid design with supramolecular chemistry? Great RNA nanoparticles with thermostability! Read about our supramolecular ionizable lipid in the latest paper from Alanna M. Manning and the #OFKLabBlueCoats https://t.co/UrRsTeOGTY @AdvSciNews