Congrats to Kai and nice to see his work in print. Was a fun little study we designed back in the day. But more for us to learn re traffickin of oligo meds
Strand-Resolved
Mapping of siRNA Trafficking in Cells
by Nanoscale Secondary Ion Mass Spectrometry https://t.co/sGbQ9Yk37x
@oligogirl@PLOSONE Interesting to have a first author with the last name βWoodcockβ on a DMD paper π. The human dose is only 25 mg, makes me wonder if there is a CpG or immunomodulatory motif hidden somewhere, I couldnβt find the ASO sequence, were you able to?
1/3. Some of my fondest memories from the 2023 OTS will be working with my fellow co-organizer @Jandritu, OTS President David Corey and the organizing committee to create the scientific program for the conference.
2/3 It's amazing how much the field has grown, the quality of the science, and the young talent raring to discover new medicines for patients in need. At the same time, we still need to ask the tough questions, challenge hypotheses and data, and hold everyone to high standards.
Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNA https://t.co/xNFWQxEGkq