New 📜 in @NatureSMB - "Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity", by Sveta in my lab, @omerz213@ericmiska and Lau and Greg @kudlalab. Been a while since preprint, so a 🧵
https://t.co/liEoe8gYQ7
<4 years ago I transitioned from academia to biotech, leaving behind some unfinished projects—but never the network of friends who kept pushing the science forward. Today one of those projects was completed: The structure-Activity of the lncRNA NORAD https://t.co/LPaoBKoPQg
Exciting news - the RNA Tech Team at Eleven Therapeutics is seeking to hire a Senior Scientist - Molecular Biology/ RNA Biology. We are looking for a creative Tech-Savvy who can drive our innovative RNA R&D forward! https://t.co/gxwTo1KBW4
Our SARS genome structures are out @TammyandLan et al. ! One of the most exciting findings was the super stable and abundant long distance (1.2kb apart) RNA interaction with the FSE that is important for high levels of frameshifting. Thanks so much to all the coauthors !
New #KwokLab paper: Identification and targeting of G-quadruplex structures in MALAT1 long non-coding RNA https://t.co/oahZR57ZPi
Congratulations to all the authors!
@NAR_Open
@CityUChem@CityUHongKong
Excited to share our new work🌶️🌶️🌶️ : The modular folding of the human long noncoding RNA NORAD in its physiological environment and under stress conditions
https://t.co/LsPiCE9YUG
Great collaboration between @IgorUlitsky@kudlalab@ericmiskalab
👉NORAD structure is modular - a previously hypothesised yet poorly established concept for lncRNAs.
👉NORAD undergoes structural relaxation upon entry to stress granules.
👉NORAD structure clusters its Pumilio recognition elements and controls their function.
#RNAstructureConference2021 What a wonderful conference! So many amazing talks! Thank you very much to all the speakers and attendees. Hope to see you in person soon.