Slowing Progression of CKD:
Slowing CKD progression is a multipronged task that includes
1. Treatment of the underlying cause of CKD.
2. Blood pressure control.
3. Use of antiproteinuric therapy (ACE inhibitor/ARB, SGLT-2 inhibitor, MRA, or combination if appropriate).
4. Weight loss in patients with obesity.
5. Avoidance of nephrotoxins (iodinated contrast agents, NSAIDs, PPIs).
6. Management of other cardiovascular risk factors.
Perioperative medication management is a common dilemma in rheumatology.
Should methotrexate be stopped before surgery? What about biologics, JAK inhibitors, and steroids?
Key principles:
• Continue most conventional DMARDs
• Hold biologics for one dosing interval before major elective surgery
• Hold JAK inhibitors 3 days before surgery
• Minimize glucocorticoid exposure when possible
• Restart therapy after satisfactory wound healing and absence of infection
A practical, guideline-based summary for daily clinical practice.
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SLE Management Made Practical
Treat the organ, not just the label.
Start with hydroxychloroquine, classify severity, taper steroids early, and focus on preventing damage.
#SLE#Lupus#InternalMedicine#Rheumatology#MedicalEducation