Olin Silander

Senior Research Fellow, Liggins Institute, University of Auckland, Tāmaki Makaurau, Aotearoa. Evolutionary biologist and wannabe microbiologist. he/him.

[Olin Silander @osilander]

Our paper on the evolution of gene regulation was published today https://t.co/Lo7pxrgJuk. Years of hard work and hard thinking by @m_vlkova. I really like this paper. (1/8)

[Olin Silander @osilander]

@baym wtaf. [deleting this reply in one hour in case my phone is ever inspected while returning to the US]

[bxv_genomics @bxv_genomics]

A High-quality Oxford Nanopore Assembly of the Hourglass Dolphin (Sagmatias cruciger) Genome https://t.co/7XU2rLOw1l

[Olin Silander @osilander]

@ppgardne Nice section header "Stop using highly curated datasets for training and testing"

[Olin Silander @osilander]

@cabbagesofdoom @rrwick @nanopore note that parsing the cigar string can't get you identity as 'M' means match or mismatch, I think the md tag would work. The .paf col division is way easier :)

[Olin Silander @osilander]

@skryazhi The Uni on the other side of the city

[Olin Silander @osilander]

yup done.

[Olin Silander @osilander]

I'm in the very lucky position of having another option, but I have excellent colleagues who do not yet.

[Olin Silander @osilander]

The disestablishment will disrupt or even destroy the trajectory of many people's careers. Not sure what else to say.

[Ryan Wick @rrwick]

New blog post: https://t.co/OWnmLPQs5g

I took the ONT data from my last post, subsampled to various depths and assembled with Flye.

Reveals what ONT-only accuracy looks like with a 'normal' read depth and Flye assembly (as opposed to extra-deep reads and Trycycler assembly).

[Olin Silander @osilander]

@bellbirdsong_NZ @Jamienzherald

[Olin Silander @osilander]

@MrsRieB Leigh Bardugo Grishaverse! Also I f he reads a lot he should be able to finish the eight or so Percy Jackson before the tv show starts in Dec. My 11yo has has read every PJ at least twice and has been waiting for two years for the tv series. Rick Riordan is great.

[Olin Silander @osilander]

@CatharineAquino @FGCZ_EN Just overall impressive or were there specific bits/methods they were most impressed by? Interested in what people see as best practices at genomics facilities (or, cutting edge practices)

[Chris Seymour @iiSeymour]

Dorado v0.4.0 is live!

- barcode demux & trimming
- simplex read splitting
- improved 6mA, 5mC/5hmC GpG models
- new 5mC/5hmC all context model
- increasing duplex pairing rates

Plus a whole bunch more..

https://t.co/tYCaHGYDCA

[Olin Silander @osilander]

@matthewmatix @Jamienzherald 2022 sign in the elevator: ISC Innovation Science Complex

[Nikki Freed @freed_nikki]

@TroyBaisden @REasther @gringene_bio @Jamienzherald It is the staff who occupy this building @masseyUni whom are being made redundant (Ecology, Molecular Bio, Chemistry, Food tech, etc). The space was purpose-built for them, opened in Feb this year. So many talented staff are being fired; terminating many postgrad projects.

[Kat Holt @pollenkat]

CATASTROPHIC LOSSES TO NATURAL SCIENCES, FOOD TECH AND ENGINEERING AT @MasseyUni PROPOSED TODAY. 60% of staff to go across these areas. Shut down of these capabilities at Albany. Engineering cut altogether. Plant science also cut. Massey: taking the 'Universal' out of University.

[Olin Silander @osilander]

@Psy_Fer_ The most confusing thing is why it helps MinION the most? Is t that the least exposed to light? As opposed to P2, gridion, and promethion, which have glass?