A.Y

제니 | nyc l'amant de nini

[A.Y @other_worldlyA]

👇

[BEST THING THAT HAPPENED IN KPOP @kpophappenings_]

if all asians look the same, then why tf don’t i look like jennie kim???

[anique | 14 days 🤍 @iqnbeneedy]

well ariana grande is touring england and not argentina so who really won

[Aakash Gupta @aakashgupta]

This isn’t a random scientist who got lucky.

Mariano Barbacid discovered the first human oncogene in 1982. He isolated H-RAS from bladder cancer cells and proved a single point mutation could trigger cancer. That finding launched the entire field of molecular oncology.

KRAS mutations cause 90% of pancreatic cancers. For 43 years, oncologists called KRAS “undruggable” because the protein had no obvious binding pocket. Barbacid spent the last decade using genetically engineered mice to systematically test every node in the KRAS signaling pathway, looking for combinations that would work without killing the patient.

The triple therapy blocks KRAS three ways at once: the main growth signal, the escape routes through EGFR and HER2, and the stress-response backup through STAT3. Cut the engine, seal the exits, disable the emergency system. Tumors vanished in mice and didn’t return for 200+ days after treatment stopped.

Pancreatic cancer has a 13% five-year survival rate. 8% for the ductal adenocarcinoma type this therapy targets. Most patients live one year after diagnosis.

The catch: this is preclinical. Human trials are 3+ years away. One of the drugs, RMC-6236, might get approved this year, but the full triple combination has regulatory hurdles.

Still. The man who discovered human oncogenes in 1982 may have just figured out how to eliminate the cancer those genes cause. That’s a 43-year arc from first principles to potential cure. Science rarely works this clean.

[jennie @jnkcvnty]

no one can top how jennie served live vocals and face card at the same time

[𝐉 @ysaaanini]

the entire J2NNI5 photobook feels like seeing an ex you're still inlove with

[ria ˙ᵕ˙ @rosiesbitchxx]

you’re sick if you find this attractive

[realer @rrrealer]

man fuck them kids

[A.Y @other_worldlyA]

RELEASE THE CREW, TAKE ACTION!!
@francediplo_EN
@francediplo
@SpainMFA
@MAECgob
@GermanyDiplo
@Itamaraty_EN
@SweMFA
@MFATurkiye
@DutchMFA
PROTECT THE FLOTILLA!! PROTECT YOUR CITIZENS!!!

[Dewey Bryan @DeweySaunders]

Free Palestine. Fuck Ice. Fuck is wrong w yall

[Rima Hassan @RimaHas]

🇵🇸⛵️🤍 #FreedomFlotilla #BreakTheSiege #Gaza

[A.Y @other_worldlyA]

PROTECT THE FLOTILLA!! PROTECT YOUR CITIZENS!!!
@francediplo_EN @francediplo @SpainMFA @MAECgob @GermanyDiplo @Itamaraty_EN @SweMFA @MFATurkiye @DutchMFA PROTECT THE FLOTILLA!! PROTECT YOUR CITIZENS!!!

[Karim Wafa-Al Hussaini @DrKarimWafa]

It’s one boat against the world.

It’s 12 people doing more than 8 billion.

All eyes on the Freedom Flotilla.

[Freedom Flotilla Coalition @GazaFFlotilla]

SOS! the volunteers on 'Madleen' have been kidnapped by Israeli forces.
Greta Thunberg is a Swedish citizen.
Pressure their foreign ministries and help us keep them safe!

Web: https://t.co/uCGmx8sn8j
X : @SweMFA
FB : @SweMFA
IG : swedishmfa

#AllEyesOnMadeleen

[m ✰ @mar3uss]

She tore that y’all can’t even lie on my sista

[carli @poisonpeachh]

dudes be named Will but won’t

[Fuckin’ Princess @8WithaTiara]

If you’re a US CITIZEN and you see ICE, just start running.
Waste their time...

[sarah @sandwichlover7]

(australian voice) i just saur naursfauraurtaur

[Henry @_hjjm]

Me having non verbal time with the pet at the party