Decepcionado con que el caso de la Reunión Anual de la SEAP titulado "Buscando en el baúl de los recuerdos" no se trate de un caso de demencia. Oportunidad perdida.
@Cristina_VargAP Where do you put the threshold between a dediff liposarcoma and a sclerosing variant of a well-diff liposarcoma? What features do you rely on to distinguish in borderline cases? Cellularity? It's just a doubt I find mysef facing from time to time. Anyway, nice case!
@JuanjoShulare Creo que da esa pinta por la retracción de los nidos. Pero vamos, que lo he tuiteado únicamente porque con semejantes nucleolos me estaba sintiendo observado yo también.
@VickeryJasmine I think it looks like a pleomorphic variant of lobular carcinoma, isn't it? The nuclei are way more atypical than the classic lobular carcinoma.
@JuanjoShulare No pretendía que fuera un juego de adivinanzas, pero puedo saciar tu curiosidad. Se trata de un carcinoma ductal infiltrante de mama, grado 3.
Uterine smooth muscle tumour showing staghorn vessels and some atypical nuclei. No mitosis. No necrosis. What's your diagnosis? Would this findings urge you to order any extra stain? #GynPath
Some of you already got the correct answer! This is a fumarate hydratase-deficient leiomyoma. Loss of immunohistochemistry stain is shown in the picture. It can be sporadic but it may be the first clue to hereditary leiomyomatosis and renal cell carcinoma (HLRCC), so look out! 🕵️♂️
Uterine smooth muscle tumour showing staghorn vessels and some atypical nuclei. No mitosis. No necrosis. What's your diagnosis? Would this findings urge you to order any extra stain? #GynPath