Great to see this out now!
Here we present a convenient route to (hopefully) useful beta-functionalized amines directly from tertiary amides.
Thanks to Sergio and Gabriele for all your help along the journey!
We're thrilled to announce that our enantioselective desymmetrization of phosphorus (V) is now out in Nature Chemistry! 🔥
Congratulations to @formica_michele and the team @tanya_rogova, Yao, Naoto, Bran, @FarleyAlistair@fjduarteg@KenYamazaki5
🎉🎉
https://t.co/INSCY0LfAU
Redox Transpositions of Tertiary Amides - now online at ChemRxiv!
Oxidation states dance in our new reductive activation of amides to enable one-pot synthesis of beta-functionalized amines.
Congratulations to @benshennan11 and Sergio!
https://t.co/EZC25YaoRM
@compoundchem Nice graphics as usual!
You might want to change the description for Irma Goldberg though, since Marta Catellani's discovered the eponymous reaction over 25 years ago now!
Massive congrats to Roman, Sam, and the team for their enantioselective total synthesis of himalensine A! 🎉
A new cyclization reaction enables efficient, enantioselective construction of the core - modelled by @KenYamazaki5 and @TrevorAHamlin.
https://t.co/gxVp8PCLxK
I'm very happy to share our latest work, published now in @ChemRxiv, the BIMP-catalysed enantioselective nitroalkane addition to unactivated α,β-unsaturated esters!
Congrats to @FarleyAlistair and Iain McLauchlan!
@OxfordSynthesis@dixon_group
https://t.co/xxF3AW9zW9
BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
Branching out: redox strategies towards the synthesis of acyclic α-tertiary ethers – our latest review out now in @ChemSocRev!
A massive collaborative effort by members of the @OxfordSynthesis SBM CDT 2020 Cohort and our own @benshennan11. Well done all!
https://t.co/DY96k6I170
@GusTheChemist @OceAlaB What do you think is worse @GusTheChemist , the awkward alkene, the terminal C3H groups, the lack of perspective in the key structural motif?
Difluoroalkylation of Tertiary Amides and Lactams by an Iridium-Catalyzed Reductive Reformatsky Reaction – out now in Org Lett! @JOC_OL
Congratulations to @PBiallas and @KenYamazaki5 🔥
https://t.co/wthEq8hFpB
Really pleased to see our desymmetrization approach to madangamine E now out in @J_A_C_S!! 🎉🥳
It's been an honour to be a part of the team and work on this #totalsynthesis with Shinya @r6vT6hSx6jdB2xP and @KenYamazaki5!
Difluoroalkylation of tertiary amides and lactams by an iridium-catalyzed reductive Reformatsky reaction out now on @ChemRxiv!
Congratulations to Phillip and @KenYamazaki5!
https://t.co/PTIKmyHKll