Arju

#prescottgenomics University of New Hampshire at Manchester

[Arju @parajuliarju]

@savahna_ Yes. What do you need help with

[Arju @parajuliarju]

I could not have agreed more

[Mutant Strong @IrinaBrooke1]

@parajuliarju Correct! And men need to get base line mammograms to keep on top of their breast health who are BRCA1 or BRCA2, as well as those with family history of breast cancer. #menhavebreaststoo #mengetbreastcancertoo #menhavebrca #mutantstrong #knowyourgrnesandgettested

[Arju @parajuliarju]

Genes such as #BRCA and #PALB2 targets to cell growing and inhibit cancer cell growth. However, when there are mutations on either #BRCA1 or #BRCA2 then, the abnormal genes poses an increased risk on breast cancer. #prescottgenomics

[Arju @parajuliarju]

@ReeInspired Wow! ❤️❤️❤️ so much love for you. You are strong and courageous to have gone through breast cancer and now are disease free. So so so proud of you. ❤️

[Arju @parajuliarju]

- I'm so happy and glad about your cancer prognosis, Congratulations! There are a lot of factor that affect the prognosis and I wish more women would seek information so that they know what treatment is best for them and if they want the treatment. #BreastCancer #personalgenomics

[Aretha Grant 🪷 @ReeInspired]

Today is a great day for me. April 25, 2014 is the day I was declared cancer free. For those who are familiar with triple negative breast cancer, you know why the 5 year mark is significant! God is sooooo good! #breastcancerawareness #breastcancer #standup2cancer

[Arju @parajuliarju]

Since FDA has approved Olaparib for patients who test positive for #BRCA and mainly have breast cancer, this could be advancement in the field of pharmacogenomics and perhaps, we might have found a cure to cancer.

[Arju @parajuliarju]

Many drugs and oral contraceptives can be used to reduce the risk of developing the mutated genes #BRCA1 and #BRCA2. To lower the cancer risks for breast cancer patients, usually tamoxifen and raloxifene is consumed. However, the drug does not promise to lower the risk of cancer.

[Medscape Pharmacists @MedscapePharm]

EC approves olaparib for #BRCA breast cancer. https://t.co/iKxr9HHyaf

[Arju @parajuliarju]

Plays a very significant role on reducing the risk of breast cancer. #prescottgenomics

[Arju @parajuliarju]

- #Breastcancer Apart from exercise, healthy diet and weight loss, factors such as: knowing what type of cancer you're diagnosed with, where it is in the body, looking for particular traits of cancer cells and how you are responding to the given treatment.

[Bosom Friends @BosomFriendsBfd]

There is so much evidence that weight loss, healthy diet & exercise can reduce the risk of #breastcancer developing.
Therefore, Cathy Tait, one of our breast surgeons, would like you to join her, to run Lister Park parkrun on Saturday 27th July at 9am.

Details to follow below

[Arju @parajuliarju]

It is also essential to know the survival statistics as there are cancer-specific, relative, overall or disease-free survival. Most women also have hard time knowing the difference between cure and remission. Nonetheless, I'm SO happy you're cancer free! #prescottgenomics

[Arju @parajuliarju]

Tumorigenesis is due to gene #BRCA. According to the study,"Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations", women are 55% to 65% carriers of BRCA1 mutated genes and will have mutated BRCA2 gene by 70 developing breast cancer #prescottgenomics

[Arju @parajuliarju]

One of the most prominent disease that women are diagnosed with today is Breast Cancer. Two genes that gives the risk to it are #BRCA1 or #BRCA2. To have #breastcancerawareness brings the light to this disease. #prescottgenomics

[Arju @parajuliarju]

According to the https://t.co/OIIZ9d9EUj, the side effects of Denosumab may range from anemia, diarrhea, nausea, itching to hypercholesterolemia, musculoskeletal pain, hypocalcemia, sciatica etc.The drug that interacts with denosumab is daclizumab. #prescottgenomics

[Arju @parajuliarju]

- Although Denosumab is the medication that treats osteoporosis, adjuvants of Denosumab has shown mixed results to prevent/treat Breast Cancer. #BRCA1 #prescottgenomics

[Arju @parajuliarju]

If the women do carry the mutation in BRCA gene, it is recommended for women to have a mammogram annually. #prescottgenomics

[Arju @parajuliarju]

Breast Magnetic Resonance Imaging is a PRIME and supplemental tool to detect and evaluate high breast cancer risk by finding mutations at #BRCA1 and #BRCA2 genes as it provides a breast screening of mammogram and ultrasound. #prescottgenomics #oncology #breastcancer

[Missy @MissAYY01]

Ugh so annoyed that I have to wait until the end of May to get my mri and mammogram. Can’t stop thinking about my #brca1 mutation and what I should do. 😫

[Arju @parajuliarju]

Oncologists recommend that women who are at risk for breast cancer go through the clinical breast examination to detect the mutation in #BRCA1 and #BRCA2 genes and particularly in age that ranges from 25 to 35 years of age. #prescottgenomics

[Arju @parajuliarju]

It is also a relief that under the #AffordableCareAct, genetic counseling and testing for BRCA are covered by health insurance. According to https://t.co/WMowfy9oki, during their lifetime; 12% women will develop breast cancer& 72% will inherit the mutated gene. #prescottgenomics

[Arju @parajuliarju]

Third party genetic testing like @23andMe has made it easier to detect the mutation of #BRCA1 and #BRCA2 gene. #Prescottgenomics #BreastCancer

[Randy C. Miles MD, MPH, FSBI @RMilesMD]

#MultigeneTesting ‘not leading to more worry’ for patients w/ #BreastCancer
https://t.co/3DlA6Wl8Ni
#GeneticTesting #BRCA1 #BRCA2
@GoHealio

[Arju @parajuliarju]

Breast cancer are only inherited in 5% to 10% in cases. #prescottgenomics

[Arju @parajuliarju]

- Germline mutation in #BRCA2 is the second breast cancer predisposing gene that poses highest risk in breast cancer by almost 90%. More than 500 mutations are found in the #BRCA2 gene. Thus, to study this gene is essential. #prescottgenomics

[Míryam Martínez @miryamartinez]

"I think that it brings power... Not simple, pretty things, but there is action that can be taken. And it saves lives." #welcometoBRCAland #BRCAntStopMe #opportunity #Empowerment #BRCA1 #BRCA2

[Arju @parajuliarju]

The screening is limited only in developing countries due to the high cost. #prescottgenomics

[Arju @parajuliarju]

The analysis of genes by genetic screening: #BRCA1 and #BRCA2 is hard even because of the size of the gene, has high mutation and rearrangement frequency and the whole DNA sequence is necessary but is possible for analysis. #prescottgenomics

[Dr Sabrina @doctor_sabrina]

Totally agree that the fact that it only looks for three pathogenic variants in #BRCA1 and #BRCA2 is not widely appreciated and could give people looking for health information in the #DTC #genetic #testing arena false reassurance

[Arju @parajuliarju]

It is also scary to think that most people who develop mutations in #BRCA1 or #BRCA2 genes do not even have family history of breast cancer. #prescottgenomics

[Arju @parajuliarju]

Genes such as #BRCA and #PALB2 targets to cell growing and inhibit cancer cell growth. However, when there are mutations on either #BRCA1 or #BRCA2 then, the abnormal genes poses an increased risk on breast cancer. #prescottgenomics

[Mutant Strong @IrinaBrooke1]

@malefitness BRCA carries should definitely be included. I would say it’s because less than 1% of men get BC. Than again, who wants to be that 1% to begin with? No one! #mengetbreastcancertoo #menhavebreasts #brca2 #brca1 #breastcancersurvivor #pinkandblue