Continuing my conference run at the microscopy and microanalysis #MM2024 meeting in Cleveland! Enjoying broadening my understanding of microscopy techniques and thankful for the opportunity to present my research today at the biomedical research session @MicroscopySoc@MSAStudent
Very excited to share this story about two substitutions in a sarbecovirus spike that enhance infectivity by increasing RBD availability. My first cryoEM structure was of the RsSHC014-CoV spike protein and is included in this manuscript! https://t.co/OyTxcCGZmR
Cool new preprint on SARS-CoV2 Omicron XBB lineage spikes: https://t.co/ktTQ828VAR
Seems like spike closure to evade the immune system is also the trajectory of SARS-CoV2, similar to what we found for the longer circulating common cold coronavirus HKU1 (https://t.co/FOBbm737OK).
Had a great time at The biophysical society meeting this past week in Philadelphia! Still processing all the awesome science I got to hear including from Carolyn Bertozzi! #BPS2024
Our study on the Langya virus fusion protein structures (pre- and post-fusion conformations) now online @JVirology https://t.co/GiszrwF7lc
1st author @Aaron_J_May will be at the 3DEM Gordon Research Seminar this weekend. Be sure to stop by his poster!
Out @biorxivpreprint today!
https://t.co/KethBzFecI
We report the pre- and post-fusion structures of the Langya virus fusion (F) protein. Langya virus (LayV) is phlyogenetically distinct from Nipah virus and Hendra virus that, like LayV, also belong to the Henipavirus genus.