The Bcl-2 inhibitor #venetoclax can selectively deplete hematopoietic stem cells and reduce radiation doses during conditioning for #StemCellTransplant in large animals, suggesting the drug could minimize toxicity and foster graft tolerance. @MGHSurgery https://t.co/VLDMSmX80A
The K-CLIER project, another great example of collaborative work on the use of AI in translational research presented by @pcippa and Daniele Malpetti. @EnteOspedaliero#SCTO Events
Kidney gluconeogenesis is responsible for 40% of systemic gluconeogenesis during fasting. This study shows that CKD disrupts kidney gluconeogesis, with systemic decrease in glucose and increase in lactate levels, and is associated with worse prognosis https://t.co/tfJXq6KO06
Happy to share our latest work in @FrontImmunol!
In this work we explore the complex landscape of multiple cytokines & chemokines in kidney transplantation:
https://t.co/9sW4sDCtdA
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⏬QPRT activity/expression, a rate-limiting enzyme of de novo NAD+ biosynthesis in acute kidney injury & chronic kidney disease
Important evidence of #ERStress in NAD+ pool depletion🥸
Dr. Pietro Cippà & Nicolas Pallet labs @JCI_insight 2022 @pcippa
https://t.co/913wDNBpyJ
ASCI member János Peti-Peterdi @KeckMedUSC on the #cover of @JCI_insight: Visualizing endothelial and immune pathogenesis in an Alport syndrome model: https://t.co/GZGq4V0RcY
#Nephrology
A newly identified gene variant helps to improve peritoneal #dialysis. #Kidney patients with this gene variant have a higher risk of death and should therefore be treated with special dialysis solutions. https://t.co/Lsl1uKR8nl
The @USCStemCell lab of Andy McMahon has identified a type of injured cell that might contribute to the transition from an acute kidney injury to chronic kidney disease, as described in a new study in PNAS. @PNASnews@KeckSchool_USC https://t.co/5AIXlVOzhA
A moving shortfilm about an extraordinary « second Life » after #kidney#Transplantation
TAYO - Deu - Kurzfilm über die Bedeutung der Verbundenheit zwischen Mens... https://t.co/AQTZT7ZaT4 via @YouTube @Swisstransplant
CURTAIN8-020: Acute kidney injury: from single cells to systemic metabolism
Speaker: Pietro Cippa @pcippa, Ente Ospedaliero Cantonale, Switzerland
#ISNWCN