Tom Fox

Pediatric infectious disease

[Raymund Razonable @RazonableMD]

Uncharted Territory ⁦@CIDJournal⁩

Clinicians often venture into uncharted territory when managing ICH patients with rare infections, where diagnostic uncertainty and absence of treatment guidelines pose significant challenges. https://t.co/ooS3VEHxSu

[Philippe Méresse @Philoulyon]

“Les pesticides, c’est simple : c’est mal.”

Cette phrase revient souvent.
Mais quand on gratte un peu… rien n’est si simple.

Voici 6 idées reçues sur les pesticides – et pourquoi la réalité est plus complexe.

#Thread #Pesticides #FrAgTw 🧵 1/9

[Brad Spellberg @BradSpellberg]

I recently evaluated a pt with a fever of 40.5 C, WBC 15,000, & hypotensive/tachycardic. I was really torn. Could the pt have inflammation of some kind? I wasn't sure. But then, thankfully, I saw that someone had ordered a CRP. And that's when I knew there was inflammation.

[𝙲𝚑𝚊𝚛𝚕𝚎𝚜 𝙲. 𝙼𝚊𝚗𝚗 @CharlesCMann]

Fresh water is our worst immediate environmental problem--and one we've known how to solve for more than a century. That we don't do it is infuriating. Part of a series about the systems that undergird our lives. (Paywall lifted for today; please pass on.) https://t.co/SZJTza5Ord

[TTS @ttsorg]

🚨4th CMV Guidelines Are Now Available! 🚨

This updated international consensus—developed by leading CMV experts—reflects major advances in CMV diagnostics, prevention, treatment, and surveillance. Don't miss this must-read guidance!

See the guidelines 👉https://t.co/0LyGBb9o08

@KottonNelson @BaanCarla @TransplantJrnl #medtwitter #transplanttwitter

[Sanjay Mukhopadhyay @smlungpathguy]

1/
In honor of beautiful Barcelona, Catalunya, Spain, and my wonderful host @SansanoValero , I would like to start a new thread called "Plata" (silver)

It will be all about the Grocott Methenamine Silver (GMS) stain. Let's start with Histoplasma

[Thomas Chatterton Williams @thomaschattwill]

I don't know what someone whose private agenda was to humiliate America and actually eliminate the remnants of her moral high ground in relation to Russia, China, et al would do differently

[Open Forum Infectious Diseases @OFIDJournal]

Characteristics of clinics offering non-traditional Lyme disease therapies in Lyme endemic states of the US

✅ Just Accepted
🔗 https://t.co/VUkyX10fQ1

[Timothy Li @drtimothyli]

Summary of new antibiotic agents for the treatment of MDR Gram negative bacterial infections

https://t.co/ZzflIG9RtH

[Mayo Clinic Infectious Diseases @MayoClinicINFD]

Publication Alert

Intracellular but not undetectable:
A case of Francisella tularensis pericarditis

Report by @MayoMN_IMRES residents and our fellows @kemarbarrettmd and @MayoCVFellows
https://t.co/r8Gb2G7ors

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

Not all hospitalized patients with infections need to be treated with antibiotics against P. aeruginosa!
🆕🔥Systematic review and meta-analysis
Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients #idxposts https://t.co/COGMHv8fU2

[The Cultural Tutor @culturaltutor]

Why does The Lord of the Rings still look so good?

Many reasons, but here's one: Minas Tirith wasn't CGI. They built a miniature version of the city and filmed that. It looks realistic — because it was real.

And this wasn't even the biggest model they made...

[Nicole Poole, MD, MPH @KidDocNic]

Register for the annual ID Conference. October 30 in person or virtual! High yield ID topics for outpatient pediatricians, hospitalists, ED or UC clinicians, MD/DO/APPs. @COpedsID @ChildrensColo #tweetiatrician @AAPColorado @aap_hpeds Register here https://t.co/bLTVowega4

[JAMA Internal Medicine @JAMAInternalMed]

This Teachable Moment highlights the potential harm of inappropriate central line blood cultures in clinical practice. @CUBoulder #TeachableMoment #CentralLine #CRBSI https://t.co/TG33bxsVJd

[Darcy Wooten she/her @Darcy_ID_doc]

So excited for @WashUID Core Didactics this morning on a highly relevant topic: antifungals!!!

[Jonathan Ryder, MD @JonathanRyderMD]

The BCx shortage has affected many of us.

In collaboration with @ValeriaFabreMD, @dan_diekema, and my mentor Dr. Van, we published in @OFIDJournal our approach to the shortage, emphasizing the importance of implementing BCx stewardship

https://t.co/5T5bdnX5DQ

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

CSF pleocytosis is an important criterion for encephalitis diagnosis
🆕️⚡️⚡️Retrospective study:
25.3% of patients with all-cause encephalitis and 23.7% of those with HSV-1 encephalitis exhibit absence of pleocytosis on initial LP. #idxposts https://t.co/hEyjkX78tT

[Amanda S. Evans, MD @asevansmd]

I led a report w/ 9 academic sites 🏥 on largest multi-site U.S. study of 2022 Human Parechovirus🦠 outbreak among young infants. This study not only sheds light on important pathogen of infants, but also highlights the power💪🏼 of #Collaboration in Science. #pedsID #IDTwitter

[Brad Spellberg @BradSpellberg]

I guess it's time for my daily rant. Im old enough to remember when this first negative day of culture nonsense started.
Back in the bad old days of the cretaceous era, when I was an ID fellow and rode the brontosaurus to work...

[Brad Spellberg @BradSpellberg]

Okay @radiokeller, you asked for a combo Abx therapy rant, so here it comes (I guess Im taking requests now! ;)).
There are 3 philosophical reasons to use combination Abx therapy (see my Mandell chapter for this discussion in detail). But they all apply differently to difft dzs.