In 1935, two American doctors examined seven women's ovaries and saw small lumps. They called them cysts and named the disease after them. They were wrong. It took 91 years to fix.
What we called PCOS is now Polyendocrine Metabolic Ovarian Syndrome (PMOS), announced today in The Lancet by an international panel of doctors and patients. The renaming followed more than a decade of consensus work and 22,000 patient and clinician survey responses.
The lumps Stein and Leventhal saw were never cysts. Modern imaging shows they were follicles, the tiny sacs inside the ovary that grow and release an egg each month, frozen partway through by a hormonal imbalance. PMOS is a multi-system disorder centered in the endocrine system, the body's network of glands that produces hormones like insulin (controls blood sugar), cortisol (the stress hormone), and thyroid hormones (set the body's metabolism). The ovary trouble flows downstream from there.
The naming choice is not academic. When doctors hear "ovary" in a diagnosis, they look at the ovary. "Metabolic" and "endocrine" send them to the whole body.
PMOS affects roughly 1 in 8 women worldwide, more than 170 million people. The WHO estimates 70% have never been diagnosed. Among those who do, 1 in 3 wait more than 2 years, and nearly half see 3 or more doctors first. The CDC reports more than half of women with PMOS develop type 2 diabetes by age 40, a risk 5 to 10 times higher than women without the condition. Around 37% have clinically significant depression, compared with 14% in women without it. Anxiety runs at 42% versus 8.5%.
A label born from a 1935 look at seven ovaries is finally going away. The new diagnostic guidelines roll out fully in 2028. By then, a woman walking into a clinic with these symptoms should hear questions about her blood sugar and her mood alongside her cycle. Those are the parts of the disease the old name hid for 91 years.
my dad paid $1,200 a year in property taxes in 1999
same house today
$33,000 a year
that’s $2,750 a month
just to stay in a house you already own
you never actually own anything
you just rent it from the government forever
Dating a first born daughter means you have 0.2 seconds to help. After that she’s climbing the counter moving the ladder and nearly dying because you took forever to help.😭
Homosexuality isn’t even a sin, or part of the 10 Commandments, but you know what is? Murder (bombing and killing civilians), stealing (wars to steal resources from sovereign nations) false witness (using God and Christianity to justify heinous and evil actions).
Women are nagged to stay fit, eat well, drink less and have babies in their 20s. Women are also blamed if late pregnancies result in miscarriages or unhealthy babies.
Meanwhile, some loser has created a micro wheelchair for men's disabled sperm.
The streets are calling.
New Orleans artist Flagboy Giz channels the spirit of Mardi Gras Indian tradition with a powerful performance of ‘We Outside’.
Watch the full show: https://t.co/eBdzImK9uf