Peter Siska

Physician Scientist @ University Hospital Regensburg

[Paolo Tarantino @PTarantinoMD]

😢

[Peter Siska @PeterJSiska]

�� Exciting data at #ESMO25!
@katy_beckermann presented the Kidney Cancer Research Consortium trial:
👉 Phase 1b/2 study of ipi + nivo + ciforadenant (A2A R antagonist) in 1L ccRCC

Immunometabolism meets IO in kidney cancer. 💥

#RCC #ImmunoOncology #ESMO2025

[Katy Beckermann @katy_beckermann]

💡 OPTIC RCC: precision oncology in action!
Using RNA-seq cluster biology to enrich for response in frontline #RCC.
🔹 76% ORR in angiogenic clusters with nivo+cabo
🔹 Ipi+nivo enrolling immune clusters next
Next steps ➡️ expand IO arm & move toward liquid biopsy to replace invasive mets bx.

So proud to contribute to this meaningful work with an incredible team @brian_rini @DrScottHaake 🙌
Huge thanks to Vindyha Data Science & Tempus— proof it can be done! 💪
#ESMO25 #KidneyCancer #TranslationalResearch #PrecisionOncology

[Peter Siska @PeterJSiska]

Wonderful seeing you again, Katy! Hard to believe how far things have come since our Rathmell*2 lab days — and how much progress we’ve seen in RCC therapies since then. Always a pleasure to catch up!!
#KidneyCancer #Immunometabolism #GU25

[Katy Beckermann @katy_beckermann]

So much of the joy of #ESMO25 comes from the people 💙 Great catching up with brilliant colleague and friend @PeterJSiska , after bonding 8 years ago under the mentorship of @JeffRathmell & @KimrynRathmell 🔬 Still deep in conversation about T-cell metabolism in kidney cancer — some things never change! #KidneyCancer #Immunometabolism #GU25

[Peter Siska @PeterJSiska]

Great thanks to the Working Group Medical Oncology (@AIO_Onkologie) for the scholarship! See you at #ESMO25

[Bundeskanzler a.D. Olaf Scholz @KanzlerScholz]

I am deeply shocked by the news of the cowardly attack on Slovakian Prime Minister Fico. Violence must not be existant in European politics. In these hours, my thoughts are with Robert Fico, his family and the citizens of Slovakia.

[Bernard A Fox @BernardAFox]

Dr @Oferman1 cancer #mmunotherapy guru @HebrewU SPECTACULAR TALK! reviews the nectin family of receptors and describes new anti-PVR AB that restores DNAM1 activity and T cell/NK cell function/Clinical trial has started at 5 sites. 22 patients doses. @sitcancer #TIMO2024

[Peter Siska @PeterJSiska]

A brand new paper from @MarinaKreutz lab showing what Hydroxyglutarate does to the immunogenicity&metabolism of myeloid and AML cells!

Possible combinations of anti-glycolytic drugs and epigenetic modulators for AML in the future? 💊🩸

https://t.co/Zt7P4320p5 @Haematologica

[Peter Siska @PeterJSiska]

Congrats Kim !!!

[National Cancer Institute @theNCI]

BREAKING: @POTUS announced his intention to appoint internationally recognized kidney cancer expert, Dr. W. Kimryn Rathmell, as the 17th Director of NCI. https://t.co/KbSatwFXsE

[National Cancer Institute @theNCI]

BREAKING: @POTUS announced his intention to appoint internationally recognized kidney cancer expert, Dr. W. Kimryn Rathmell, as the 17th Director of NCI. https://t.co/KbSatwFXsE

[Journal for ImmunoTherapy of Cancer @jitcancer]

New #JITC article: MCT4 blockade increases the efficacy of immune checkpoint blockade https://t.co/DmVPuBBYRM @BablNathalie @MarinaKreutz

[Peter Siska @PeterJSiska]

@ApostolovaPetya @JEdwardsHicks @NatImmunol nice work, congrats!!

[Peter Siska @PeterJSiska]

It was a great honor to present at the JSIC7 as a keynote speaker!

Thanks to Wolf Hervé Fridman and Eric Tartour for this opportunity and to the whole organizational team for great work!

#Immunotherapy #CancerResearch #metabolism

[La Revue Immunité & Cancer @ImmuniteCancer]

𝗝𝗦𝗜𝗖𝟳 - 𝗥𝗗𝗩 𝗹𝗲 𝟯𝟭/𝟬𝟭 𝗮̀ 𝟭𝟳𝗛𝟬𝟬 𝗽𝗼𝘂𝗿 𝗹𝗮 𝘁𝗮𝗯𝗹𝗲 𝗿𝗼𝗻𝗱𝗲 "𝗘𝗻𝗷𝗲𝘂𝘅 𝗲𝘁 𝗱𝗲́𝗳��𝘀 𝘀𝘂𝗿 𝗹’𝗮𝗰𝗰𝗲̀𝘀 𝗮𝘂𝘅 𝗻𝗼𝘂𝘃𝗲𝗹𝗹𝗲𝘀 𝗶𝗺𝗺𝘂𝗻𝗼𝘁𝗵𝗲́𝗿𝗮𝗽𝗶𝗲𝘀" ➡️ 𝗜𝗻𝘀𝗰𝗿𝗶𝗽𝘁𝗶𝗼𝗻 : https://t.co/cyTYMRhZth
#JSIC #immunooncologie

[Peter Siska @PeterJSiska]

How are CD8 T cells in human tumors epigenetically "ticking"?

Happy to share a new paper @MolecularCell where we collaborated with Chris Schmidl and his team to get new insights on TIL from kidney cancer and other tumors!

[Molecular Cell @MolecularCell]

Online Now: Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8+ T cells https://t.co/oN1QUuVp7Q

[Peter Siska @PeterJSiska]

Got a chance to listen to excellent talks @KeystoneSymp #Immunometabolism and also to give a talk about our work in #COVID19 Immunometabolism!

Btw, altitude sickness + jet lag is a weird combination :)

[Lydia Lynch @lynchielydia]

Kicking off the Keystone with exciting talk by our Keynote speaker @JeffRathmell with 3 stories, all unpublished! @KeystoneSymp

[Nature Communications @NatureComms]

Our editor @DrTimPImmuno is attending the #ImmunoMetabolism @KeystoneSymp in Keystone Colorado. Reach out to him to learn more about @NatureComms or to discuss potential submissions in the field of immunology and immunometabolism. https://t.co/5AlfD05uCD

[Peter Siska @PeterJSiska]

Medizinische Hilfe für die Ukraine
https://t.co/FZ5QHiPDVS

[Jonathan Lis @jonlis1]

One of the most extraordinary videos I’ve ever seen. The first woman is holding up a sign that says ‘two words’.

[Peter Siska @PeterJSiska]

n=2 -> Nature?

I beautiful paper with cutting-edge technologies, a ton of data, and a hot topic. But still, n=2.. come on :)

https://t.co/vSQFuOCMh5

[Nico Gagelmann @NicoGagelmann]

Explain to a patient risk and benefit of a stem cell transplant...#bmtsm