Pamela Wiltfang

[Dr. Brandon Beaber @Brandon_Beaber]

A 58-year-old woman taking rituximab had an MRI consistent with multiple sclerosis (A), but upon worsening symptoms, a new MRI revealed a large enhancing lesion (b/c). Diagnosis? Hint: you and ChatGPT will fail to guess this one.

[ANCA Vasculitis News @AncaVasculitis]

ANCA-associated vasculitis patients show signs of greater immune activity than healthy people, even when symptoms are absent, a study found. https://t.co/QVeTJtNb1L

[ANCA Vasculitis News @AncaVasculitis]

At diagnosis, half of adults with ANCA-associated vasculitis already have signs of interstitial lung disease, a study in Italy found. https://t.co/RXwkpDuIqo

[ANCA Vasculitis News @AncaVasculitis]

Lung complications are common in AAV, affecting four in five patients, with some developing lasting damage, a study found. https://t.co/165OcMiBfa

[ANCA Vasculitis News @AncaVasculitis]

Adults with AAV and MPO antibodies experienced cardiovascular events earlier than those with PR3 antibodies, a French study reports. https://t.co/8aXOw9XtSp

[ERA - European Renal Association @ERAkidney]

🎙️In this episode of A Pinch of Salt, we explore the role of Avacopan in ANCA-Associated Vasculitis. Lorraine Harper from the University of Birmingham shares insights on pathophysiology, current therapies, and future treatment possibilities.
🔗 3 episodes are now available on Apple Podcast, Spotify, YouTube, Amazon Music, and more!
🎧 Hit play now 👉 https://t.co/5jw2g95C1j

[Andreas Kronbichler @AKronbichler]

In our most recent paper, we have evaluated the integrate safety of Avacopan in the Phase II and III program. We found reductions in the AE rate, SAE rate, infections AE rate and no increased risk of hepatic toxicity! https://t.co/27T0nsHQ97 #300 on PubMed for me!

[Dr. John Cush @RheumNow]

Avacopan Versus Prednisone Taper in Patients With ANCA-Associated Vasculitis Without Kidney Involvement in a Phase 3 Trial

Sponsored by Amgen

https://t.co/3naFk7BGS0

[Jorge Álvarez Troncoso @joraltron]

Avacopan versus prednisone taper in patients with ANCA-associated vasculitis and ear, nose, or throat involvement
Prof. Peter A Merkel #EULAR2024

[Dr hanady manasfi @hanadymanasfi]

#Avacopan in ANCA vasculitis
#EULAR2025
@TerrierBen

[Conrad Fischer @SeeFisch]

•Avacopan is a…
•C5 inhibitor used in…
•ANCA positive vasculitis such as….
•GPA and ….
•Microscopic polyangiitis
•Avacopan helps decrease…
•Steroid use
see the UPPER respiratory abnormalities of GPA (wegener's) below

[Dr hanady manasfi @hanadymanasfi]

#avacopan #eular2025

[ACR_Journals @ACR_Journals]

✨ Top 10 most-viewed articles published in ACR Open Rheumatology in 2025 ✨
3️⃣ Safety of Avacopan for the Treatment of ANCA-Associated Vasculitis: Combined Data From Three Clinical Trials
https://t.co/JsiSjn4hI5

[Robin Sia @robinwjsia]

Avacopan can be used as induction for ANCA vasculitis.

[Roxana González @RoxOsler]

ANCA-associated vasculitis: Advances in the treatment
🔹Glucocorticoid-sparing strategies validated
🔹Rituximab remains central in induction & maintenance
🔹Avacopan improves renal outcomes & QoL
🔹Novel agents: next-gen anti-CD20, CAR-T, C5a inhibitors https://t.co/7iSJi7p7xV

[İlay Berke @ilayberke]

Our first publication of 2026 is out, and I am more than happy🎉
👉Real-world AAV data show ~90% remission with avacopan; a chance to⬇️cumulative GCs
👉High rate of hepatotoxicity in Japanese studies; a safety signal not evident in trials
Read it here 👇
https://t.co/SMifxvtDEA

[KIReports @KIReports]

Systematic Review of Efficacy and Safety of #Avacopan in #RealWorld Clinical Practice

#VisualAbstract by @Cteodosiu

https://t.co/oYPe8WdoZT

[Aravind Palraj @Rheumat_Aravind]

ANCA-associated vasculitis management has shifted.

It’s no longer steroid-heavy by default.

Severe disease → Rituximab or Cyclophosphamide
Relapsing / PR3-ANCA → Rituximab preferred
High infection risk → Minimize steroids; consider Avacopan

Steroid-sparing is the new standard.

#Vasculitis #ANCA #Rheumatology #Avacopan #Rituximab @DrAkhilX @IhabFathiSulima @DurgaPrasannaM1 @DocPriyamMD @ArunKumarKedia2 #Glomerulonephritis #AutoimmuneDisease #MedEd #RheumTwitter

[Robin Sia @robinwjsia]

An important differential for IgG4RD is ANCA vasculitis. Other include Sjogren's, Sarcoidosis, Histiocytic disorders and malignancy.

[ASN Publications @asnpublications]

This #ASNCJASN study looked at kidney transplant outcomes in children with ANCA-associated vasculitis. Researchers studied 72 patients who received transplants, finding that 97% were alive and 86% had functioning grafts after a median follow-up of 53 months. Read more: https://t.co/OhIVOGIG6j