Carmen Gu Liu, PhD

Phage-antibiotic synergy | Synogram | Phage therapy | Viromics | Graduate student | Maresso lab | Baylor College of Medicine | Penn State Alumna | Panama 🇵🇦

[Masa A. Shimazoe @MasaAShimazoe]

My first, first author paper is now on bioRxiv! 🤩

Linker histone H1 is a liquid-like "glue" condensing chromatin, which revises textbooks! 📖✨
https://t.co/ASW9Vxxhro

Huge thanks to my PI, @kazu_maeshima, for supervision.
Amazing collab with @rcollepardo’s group!" (1/n)

[Carmen Gu Liu, PhD @PhageAnt]

I received many inquiries regarding the Synogram, specifically on how to perform one. Below is a protocol that I wrote. Enjoy and blessings to your experiments!

https://t.co/7E4L4VkDO6

#Synogram #phageantibioticsynergy #phageantibiotic #synergy

[Carmen Gu Liu, PhD @PhageAnt]

Just out! COBRA

COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes

https://t.co/lPzOLzEhk3

[Dr. Sabrina Green, PhD @MotherOfPhage]

I SAID YES!!! ❤️ ❤️ ❤️ 😭 😭 🥺LinkedIn asked me if I’m still a postdoc 😢

[Dr. Amy Lee @minisciencegirl]

Never name a manuscript draft "_FINAL"

[Pilhofer Lab @PilhoferLab]

Bacteria can be pirates too... 🏴‍☠️ Let us introduce you to Captain Aureispira ⛵️ A bacterial pirate ship loaded with canons 💉 and grappling hooks 🪝🌴predating on other bacteria 🦠 Check the preprint: https://t.co/YxIi0NHiWA #predation #T6SS #T9SS #cryoEM #cryoET #teamtomo 🧵1/6

[Carmen Gu Liu, PhD @PhageAnt]

"Importantly, we also demonstrate phage-mediated L-form switching of the urinary tract pathogen Enterococcus faecalis in human urine, which underscores that this escape route may be widespread and has important implications for phage-and endolysin-based therapeutic interventions"

[Carmen Gu Liu, PhD @PhageAnt]

Came across a really cool paper about phages and L-form bacteria: "L-form conversion in Gram-positive bacteria enables escape from phage infection"

Source: https://t.co/N05ZNqaSBL #phage #evasion #phageinfection #bacteriphage

[Carmen Gu Liu, PhD @PhageAnt]

"Here we show that in osmotically stabilized environments, Listeria monocytogenes can evade phage predation by transient conversion to a cell wall-deficient L-form state"

[Carmen Gu Liu, PhD @PhageAnt]

@MotherOfPhage xDDD

[Amar Deep @iamamardeeep]

In this bioRxiv preprint, we (@_KevinCorbett ) present the architecture and activation mechanism of the PARIS antiviral defense system. Thanks to our co-authors, @Lisa_Liang13, @EnustunEray, and @PoglianoJoe, for their support in shedding light on this Anti-anti-defense system.🧵

[Muhammad Sajeer @Sajeerp_]

I'm in my 4th year of #PhD, worked in different labs around the world, heard from several postdocs, PhDs and UG's...

Dear supervisors, here are my suggestions to make your research lab a better place & attract talent!
@PhDVoice
@PhD_Genie @AcademicChatter
@AcademicDilemma

[PhD_Genie @PhD_Genie]

Complete this sentence:

Having a PhD doesn't necessarily mean that you are smart. But it does mean that you are ______________

[The PhD Place @ThePhDPlace]

Live footage of me writing this paper https://t.co/UadiimgjCG

[Nature Reviews Microbiology @NatureRevMicro]

Alternative therapeutic strategies to treat antibiotic-resistant pathogens

https://t.co/csOpWRzouU

In this Review, MacNair, Rutherford & Tan explore the potential of non-conventional therapeutic strategies in the fight against antibiotic resistance.

[ASM @ASMicrobiology]

In people with cystic fibrosis, P. aeruginosa isolates from the same sputum sample have diverse antibiotic resistance profiles, which may explain the discrepancy between in vitro & in vivo antibiotic efficacy when treating infections. @JournalSpectrum: https://t.co/NrzVjuVvDO

[Carmen Gu Liu, PhD @PhageAnt]

Phd

[Martha Clokie @MarthaClokie]

Sheffield #BioFest, was fab! Great to talk with so many folk about phages and hear their insights.Thanks to the Sheffield microbiologists for the company and delicious curry after. Snaps are of Luke Jerram's giant E coli and glass T4, so beautiful, do go and see them if you can!

[Simon Roux @simroux_virus]

!! Release update !!
If you uses iPHoP for phage host prediction: we just released a new version (1.3.3), alongside an updated host database now based on GTDB r214. Updated code and database available via conda / Docker. Please report any issues to https://t.co/1IBRetX6HV

[Nature Reviews Microbiology @NatureRevMicro]

Machine learning for microbiologists

https://t.co/lIuiN4ZHQn

In this Review, Segata, Waldron and co discuss key concepts of machine learning that are relevant to microbiologists and provide them with a set of tools to apply machine learning in microbiology research.