Leo2214

Diagnosed since 2015, TLD baby ❤️❤️❤️ UD since 2017 and counting U=U

[Leo2214 @positive4ever]

@wildflower_2021 RITM pa din

[dr. Adam Prabata @AdamPrabata]

Semua kemajuan di pencegahan dan penanganan HIV adalah kabar baik.

Hingga saat ini, vaksin HIV belum berhasil ditemukan, meskipun banyak uji cobanya, karena virus ini mudah bermutasi dan menyerang sistem kekebalan tubuh sendiri.

Nah, penelitian ini menggunakan vaksin bernama GT1.1 Env trimer yang pada uji klinis fase 1 berhasil memicu respons imun yang tepat pada 47 dari 48 orang yang diuji.

Sederhananya vaksin GT1.1 ini dirancang secara presisi untuk mengaktifkan sel B precursor di tubuh manusia. Sel ini nantinya bisa menghasilkan broadly neutralizing antibodies (bnAbs), yaitu antibodi yang bisa menetralkan hampir semua varian HIV karena menarget bagian virus yang tidak bisa berubah, seperti CD4 binding site / CD4bs dan trimer apex.

Kabar baiknya juga vaksin ini aman dan dapat ditoleransi dengan efek samping ringan.

Namun, ini baru langkah awal, masih butuh penelitian uji klinis fase 2 dan 3 untuk benar-benar memastikan keefektivannya.

Semoga kedepannya vaksin untuk HIV benar-benar bisa ditemukan.

Semoga bermanfaat!

Sumber:
Precise targeting of HIV broadly neutralizing antibody precursors in humans

[Leo2214 @positive4ever]

@discreetudpoz @positive4ever

[Leo2214 @positive4ever]

@sexdoctordeano And would you advise din po ba for bottoms to use this?

[Leo2214 @positive4ever]

@sexdoctordeano How can we buy it po Doc? 😊

[Leo2214 @positive4ever]

I say may si kuya👍

[AltIndayBadiday @AltIndayBadiday]

Survey: May napipisil ka na bang presidentiable sa 2028?

Kuya: “Gusto kong pisilin mukha ni Sara… Yun lang!” 😭😭😭

JOJOWAIN KO KUYA!!!
CHARitable! 🤣😂🤪

[Massimo @Rainmaker1973]

The end of HIV infections may be closer than we think.

Scientists cut HIV out of immune cells using CRISPR.

And the cells stayed HIV-free even after re-exposure. A cure could finally be within reach.

In a groundbreaking advance, scientists at Temple University have successfully used CRISPR/Cas9 gene editing to eliminate HIV-1 DNA from the genomes of human immune cells.

Unlike existing treatments that suppress the virus, this method completely removes the genetic blueprint of HIV from infected T-cells.

[Torey Canino-Celis @tj_canino]

may something talaga kay earl like gets ba 'yung “can i use you” yes earl everyday all night 🥵

[Leo2214 @positive4ever]

@IanEsguerra Isa sa walang silbi g congresan sa HCOJ, halatang sawsawero at wala naman puwang mga kinukuda 🤣🤣🤣🤣🤣

[Leo2214 @positive4ever]

@coconut_block @newswatchplusph @bongbongmarcos sana panooring mo ung interview plus comment po nito! Pampamulat sa inyo sa Government

[Leo2214 @positive4ever]

@gmanews Honestly ndi pa din ako supporter ni BBM but the way he listen and look others do (community pantry and sagip saka (@kikopangilinan) it shows good help kahit papaano.

[Leo2214 @positive4ever]

@mclovindelacruz @the_master_gian @pakekobutpinoy @PAWSPhilippines @AKFanimalrescue @PAWSPhilippines @pnppio

[Leo2214 @positive4ever]

@Kunarsisa @Young8Poz Online po, and take naote ndi pa naabot ng 1k ung akin around 700+ plang pero rejected na 😔

[Leo2214 @positive4ever]

@Kunarsisa @Young8Poz Same tayo, how I wish makapagtry pa ulit dito pero not for the expense ng CD4 level ko.

[Smart Science @SmartScience]

Medical researchers have successfully utilized precise molecular scissors to physically cut out latent retroviral genomes from infected host cells. This advanced gene-editing technique targets the deeply hidden viral reservoirs that traditional treatments simply cannot reach.

With tens of millions of people currently relying on daily antiretroviral drugs, a functional cure would completely revolutionize global healthcare systems. Virologists suggest this could shift patient care from chronic, lifelong symptom management to a single, permanent intervention.

The CRISPR-Cas9 system works by deploying a specialized guide RNA to locate the exact sequence of foreign viral material integrated into human chromosomes. Once located, an enzyme slices the DNA, completely disabling the pathogen and allowing the cell to heal naturally.

What makes this specific approach so groundbreaking is its proven ability to stop the virus from reactivating during periods of immune stress. In laboratory models, cells treated with this targeted therapy remained entirely free of infection even when deliberately exposed to new viral triggers.

While transitioning from cellular models to widespread human clinical trials is the next major hurdle, the scientific community remains highly optimistic. Perfecting the delivery mechanisms for these microscopic tools could ultimately bring an end to one of humanity's most persistent epidemics.

Do you believe we will see a complete, global cure for HIV in our lifetime?

[Leo2214 @positive4ever]

@manayleila @kikopangilinan

[PPopRice | MyPh🇵🇭BL @MyPhBoysLove]

getting ready for #misterpampanga2026 @ Jolo Eries Basa Babor #asian #Filipino #pinoy #gym #bagets

[Leo2214 @positive4ever]

@rssllmnz_ @ABSCBNNews @ANCALERTS @_KarenDeGuzman @_KarenDeGuzman not depending the suspect pero uso man lang magresearch, magtanong sa expert, at magredact before mo sana binuo headline mo! PLHIV is still human SHUTA KA!

[Leo2214 @positive4ever]

@r03172023 Mine hehe jk