Purnima Ravisankar

Graduate student @WCM_IMP

[Melody Zeng @melodyzeng]

Thrilled to share the 1st cancer paper out of our lab @Cancer_Cell !😀@hilalbashir65 @WeillCornell

We show chronic stress drives translocation of gut bacteria w lytic phages to tumors&unleashes an phage-fibroblast-B cell circuit to promote tumor growth

https://t.co/NdS7ikjHoG

[Nature Rev Immunol @NatRevImmunol]

Bacterial serotonin induces Treg cells in neonates https://t.co/83wt0Bar5s

[Britt Adamson @bsadamson]

Excited to share with you our manuscript describing the endogenous protein La as a mediator of prime editing and the development of our PE7 editor, which can improve prime editing. For more, please check out https://t.co/KBEz9LDsvm

[Ann Cirincione @AnnCirincione]

Excited to share our work in the @bsadamson lab using prime editing for multiplexed dropout screens! We built a platform that can reach high-efficiency editing and tested 240,000 epegRNAs for phenotypes. We saw phenotypes we expected and a few we didn't - check here for details!

[Science Immunology @SciImmunology]

New research in mice finds that gut #microbes increase #serotonin (5-HT) availability in the neonatal small intestine, promoting regulatory T cell development and tolerance to commensal and dietary #antigens. @sanidad_kz @melodyzeng @WeillCornell

📄: https://t.co/U8jBMhiFmi

[Melody Zeng @melodyzeng]

Thrilled to share our new work out today in @SciImmunology!🥳 @sanidad_kz

We show that neonatal gut bacteria make serotonin to promote gut regulatory T cells and immune tolerance against gut bacteria & food antigens.

https://t.co/dsb9pW80J1

@WeillCornell @WCMpeds @CornellCFI

[Eszter Posfai @EPosfai]

Introducing efficient prime editing in early mouse embryos, aka PEmbryo! https://t.co/q1tXgYCN0A Product of a wonderful collaboration with my friend and colleague @bsadamson, spearheaded by amazing trainees Ryan McNulty and @rpkimyip. In brief:

[Britt Adamson @bsadamson]

Excited to share our work mapping the PARP inhibitor response network! We measured ~300,000 genetic interactions, describe the genome stability network, identify context-dependent GIs revealing unknown PARPi responses, and more—check here for details! https://t.co/9FLG9euQi1