predictepilepsy

For insights and updates on prognostic models in epilepsy.
Hosted by Kai Michael Schubert and Marian Galovic.
✉️ Get in touch: [email protected]

[predictepilepsy @predictepilepsy]

🚀 Why it matters
Support for patients & clinicians in everyday life (driving, treatment).
And with COSY + NNT + RRR we can:
✔ Define cut-offs & ranges for prevention studies
✔ Improve trial design
📖 Schubert KM et al. Epilepsia 2025. doi: 10.1111/epi.18602
#Epilepsy

[predictepilepsy @predictepilepsy]

⚡ Epilepsy as a dynamic disease
The current definition (≥60% 10-year recurrence risk) is a strong foundation.
But it implies long-term risk, while many key decisions depend on the next months to years.
#Epilepsy #SeizureRisk #Neurology

[predictepilepsy @predictepilepsy]

🔮 Tools to complement
COSY = Chance of Seizure in the Next Year
Prognostic models: SeLECT, CAVE, RISE
👉 Try them at https://t.co/wQV6MAU5uE
They support driving & treatment decisions with individualized, near-term risk estimates.
#EpilepsyResearch #PredictiveMedicine

[Marian Galovic @GalovicMarian]

🧠 Pop quiz: Which disorder eats away brain volume fastest?
A) Alzheimer’s disease
B) Subarachnoid hemorrhage
C) Autoimmune encephalitis
D) Status epilepticus
(Answer below 👇)

[predictepilepsy @predictepilepsy]

�� Read the full paper 👉 https://t.co/cpybmfcr6T
🌍 Learn more about the SeLECT Consortium 👉 https://t.co/mMOHUxF5fI
🐦 Stay connected:
Instagram: @predictepilepsy | Twitter/X: @predictepilepsy
#EEG #PostStrokeSeizure #EpilepsyRisk

[predictepilepsy @predictepilepsy]

⚡️ EEG after stroke isn’t “just a snapshot” — it’s a window into long‑term risk.
Our new paper in Annals of Neurology shows how early EEG findings can help to predict post‑stroke seizures.
Introducing: SeLECT‑EEG - Here’s what we found👇
#Epilepsy #SeLECTEEG #NeuroTwitter

[predictepilepsy @predictepilepsy]

4/
💡 What this means for practice:
✅ Tailored patient counseling
✅ Smarter follow‑up schedules
✅ New avenues for targeted prevention trials in post‑stroke epilepsy
#StrokeCare #EpilepsyResearch

[predictepilepsy @predictepilepsy]

5/
🔮 The future of epilepsy & driving:
• Personalized calculators 👉 https://t.co/5x3wAG3lXz
• Wearables + AI
• Harmonized global policies
• Self-driving tech = new opportunities

📖 Read the study:
https://t.co/pGIGWzSKhZ
#DigitalHealth #NeuroInnovation #EpilepsyTech

[predictepilepsy @predictepilepsy]

1/
🚗 People with epilepsy (PWE) can drive—but not under outdated bans.
Today, eligibility is based on calculated seizure risk.

How is that risk determined? Enter the COSY model.

📄 Driving in People with Seizures and Epilepsy
🔗 https://t.co/pGIGWzSKhZ

#DrivingWithEpilepsy

[predictepilepsy @predictepilepsy]

4/
⚠️ COSY is helpful but not flawless.
• Oversimplifies real-world factors
• Ignores lifestyle & adherence
• Rarely used directly in clinical guidelines
Still, it's a powerful step toward fair, data-based licensing.
#MedicalAI #NeuroPolicy #EpilepsyCare

[predictepilepsy @predictepilepsy]

6/6 💾 Save this tool.
🔁 Share with your stroke/epilepsy team.
🧠 Tag a neurology colleague!
#NeuroTwitter #StrokeCare #PostStrokeSeizures #MedEd #BrainHealth #EpilepsyPrediction

[predictepilepsy @predictepilepsy]

🔵 DIAS3 Score: Predicting Epilepsy After CVT
A validated, regression-based bedside tool to estimate epilepsy risk after cerebral venous thrombosis (CVT).
📚 Lindgren et al., JAMA Neurology (2024)
🌍 International CVT Consortium, ACTION-CVT, Israel CVT
#StrokeCare #Neurology

[predictepilepsy @predictepilepsy]

5/6 ⚠️ Why It Matters
• ~11% of CVT pts develop epilepsy
• First seizure usually <5 months
• High-risk (ICH+SE): up to 83% @ 3 yrs
💬 Enables personalized counseling & ASM decisions
📖 Lindgren et al., 2024 — JAMA Neurology
#EpilepsyCare #CVT