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Step 3:
276mg ÷ 18mg/mL = 15.3mL. The closest available answer was 15mL.

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A 82YO male has an unsafe swallow. He now has an NGT. He takes 300mg NOCTE phenytoin sodium. Phenytoin base is a liquid. 100mg of phenytoin sodium ~ 92mg phenytoin base.

What volume of 90mg/5mL Epanutin® suspension (phenytoin base) should be administered?

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Step 2:
90mg/5mL phenytoin base is equivalent to 90mg ÷ 5mL = 18mg/mL.

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Hyperkalaemia is typically seen in acute digoxin toxicity.

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A 76YO has presented with nausea, vomiting, confusion and abdominal pain. ECG demonstrates atrial fibrillation with slow ventricular response. He takes digoxin for atrial fibrillation.

Which of the following electrolyte abnormalities increases the risk of digoxin toxicity?

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The electrolyte abnormalities hypomagnesemia, hypercalcemia, and hypokalemia lead to increased sensitivity to digoxin making digoxin toxicity more likely even with a lower concentration of serum digoxin.

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A 16YO female has taken 27x 500mg paracetamol tablets together after an argument. She took the tablets at 16:00 and immediately told her Mum who has brought her to hospital. It is 16:40. Weight 53kg.

What is the next most appropriate step?

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The normogram can be found in the “Poisoning, Emergency Treatment” summary of the BNF. https://t.co/X567RD8p40.

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*PLT = psychiatric liaison team; *NAC = n-acetylcysteine