Prof of Pot

Ph.D. scientist with 15 years of research experience. Consultant in the cannabis industry. I write about the science of cannabinoids at

[Prof of Pot @profofpot]

You may have heard that CBD is a great way to boost your levels of anandamide. I evaluate the evidence and see that the case for this is weak: https://t.co/T2w9f0YQw2

[Prof of Pot @profofpot]

Tetrahydrocannabiphorol (THCP) is the latest cannabinoid. What do we actually know about it and what could happen once it is commercialized? https://t.co/HOhckTfuZi

[Prof of Pot @profofpot]

The noradrenergic system is not as famous as the serotonergic or dopaminergic systems, but it is still important for several effects of cannabinoids: https://t.co/oKozekiAaT

[Prof of Pot @profofpot]

Your genetics determine part of your risk for developing PTSD. Genetic variants in the cannabinoid CB1 receptor and FAAH enzyme contribute to this: https://t.co/Ai903RXC1c

[Prof of Pot @profofpot]

How are endocannabinoids involved in post-traumatic stress disorder (PTSD) and how might cannabinoids be useful for treatment? https://t.co/ZI5cQtC9ut

[Prof of Pot @profofpot]

Serotonin is important for regulating pain, mood, cognition, and more. Here is why the serotonergic system is important for certain effects of THC and CBD: https://t.co/R8sl83fPz4

[Prof of Pot @profofpot]

The endocannabinoid system may be involved in the pathophysiology of depression, but it may also offer new opportunities for treatment:
https://t.co/XLdrLbM3DG

[Prof of Pot @profofpot]

Here is how your FAAH enzyme genotype affects pain and response to opioids: https://t.co/8bxvg134v6

[Prof of Pot @profofpot]

@cannaworldsite @CannifyUS @TheWeedBlog I acknowledge not minor by abundance in the plant (I state this in the first paragraph of the article). But minor based on consumption and how much we know about it.

[Prof of Pot @profofpot]

THCA is a minor cannabinoid that can potently activate a nuclear receptor called PPARγ. Although it could be neuroprotective, we have no data from clinical trials: https://t.co/m7Mb4UDotr

[Prof of Pot @profofpot]

CBN is claimed to have sedative and sleep-promoting effects. The problem is that very little of the extensive research on CBN actually support this: https://t.co/bLynceyuAH

[Prof of Pot @profofpot]

CBG is a minor cannabinoid that has a variety of pharmacological activities, but the most unique one is not yet proven: https://t.co/mChcCGSOeB

[Prof of Pot @profofpot]

CBDA is much more potent at the 5-HT1A receptor than CBD. This could mean improved therapy for nausea/vomiting and anxiety, but clinical trials are lacking: https://t.co/LRv6V1X9Dh

[Prof of Pot @profofpot]

CBDV is a minor cannabinoid with activity in animal models of epilepsy, autism spectrum disorders, and neuropathic pain. Several clinical trials have been initiated in these conditions: https://t.co/nyfV7OcSQI

[Prof of Pot @profofpot]

THCV is a minor cannabinoid which can block activation of the CB1 receptor. Although it had potential in type 2 diabetes, it failed a Phase 2 trial: https://t.co/yxrKTlmDF3

[Prof of Pot @profofpot]

The therapeutic potential of minor cannabinoids is often exaggerated. Here are 5 things you need to know to critically evaluate the latest research: https://t.co/565QqU6gD0

[Prof of Pot @profofpot]

The cannabinoid CB2 receptor has important regulatory functions in the brain. Your risk of several psychiatric diseases may be heightened if you have certain genetic variants: https://t.co/PCfdnnIBz0

[Prof of Pot @profofpot]

The cannabinoid CB2 receptor is critical for limiting inflammation. Your risk of many immune diseases may be heightened if you have this genetic variant: https://t.co/D0PjBML4WB

[Prof of Pot @profofpot]

Cannabis has been linked to aggression despite having the opposite effect in most people. A polymorphism in the serotonin 5-HT2B receptor may be one explanation: https://t.co/umRDlLpVPv

[Prof of Pot @profofpot]

People with low activity of the GABA-A receptor are more susceptible to psychotomimetic effects of THC. Here’s how some cannabis terpenes may help: https://t.co/UPrwk3hF5y