Proteomics Resource Centre (PRC)

Proteomics Resource Centre (PRC),Faculty of Medicine, University of Ottawa, located in the RGN Campus, 451 Smyth, Ottawa, On

[Proteomics Resource Centre (PRC) @proteomics_core]

Please double-check the service price from our website https://t.co/n5QWZevJWK, get a quote and approval from your PI before sample shipment.

[Proteomics Resource Centre (PRC) @proteomics_core]

Do NOT mess up N-term Acetylation for buttom up proteomics search. N-term Acetylation only occurs on protein N-terminal naturally and frequently (80%~90% in human), unless it is introduced on purpose. Therefore, be sure to set Protein N-term aceylation, instead of on any N-term

[Proteomics Resource Centre (PRC) @proteomics_core]

You probably do not believe that this is the human protein profile from nearly 500 stool samples (green as zero), with more than 4000 human proteins quantified. A clear pattern is observed, so what is the next step?

[Proteomics Resource Centre (PRC) @proteomics_core]

Just finished a DIA proteomics profiling hundreds of samples, from a perfect experimental design with enough biological and technical replicates. The dataset produces a quantification matrix of over 10k proteins, with clear pattern across groups! Super!

[Proteomics Resource Centre (PRC) @proteomics_core]

Dare you believe that a dirty needle seat could possibly demolish your analysis simply by capturing your hydrophobic peptides? Surprised to see the difference after only replacing a needle seat. Keep eyes on the pressure increase while sample loading with "dirty" samples

[Proteomics Resource Centre (PRC) @proteomics_core]

It seems Diann wins Maxquant for this round. Data from DIA analysis of 12 mouse plasma test runs using short gradient on Astral. Speed is not even comparable yet.

[NorthOmics lab @NorthOmics]

We are excited to announce that starting from today, MetaLab starts supporting DIA (Data-Independent Acquisition, without DDA based library). Checkout https://t.co/bpeAEJxCFl for early bird testing. Poster is also available on @asms2024

[NorthOmics lab @NorthOmics]

Finally, Astral is ready to fire

[Proteomics Resource Centre (PRC) @proteomics_core]

Lucky that the UHV turbo on our 10-year-old QE died but not shattered, only with seized bearing, and some debris. Cleaned out, and hopefully will be no charging effect.

[NorthOmics lab @NorthOmics]

Brain health is linked to gut health. We study whether nutritional intervention with personalized, preselected prebiotics can improve brain health in those living with mild cognitive impairment or dementia/Alzheimer’s disease. check out https://t.co/e9UgQ67wHw

[NorthOmics lab @NorthOmics]

Do you live in the Ottawa region? Do you live with mild cognitive impairment or Alzheimer’s disease? Are you interested in participating in a research study? Call us at 613-562-6328 or email [email protected]. For more information check out https://t.co/e9UgQ67wHw

[Proteomics Resource Centre (PRC) @proteomics_core]

New business from Proteomics Resource Center! Offering customized laser-pulled ESI tips! contact us for more details...

[NorthOmics lab @NorthOmics]

Ask the New Bing about iMetaLab

[NorthOmics lab @NorthOmics]

As announced at #hupo2022, MetaLab MAG version is now released. With faster and better id and quant, please check it out at https://t.co/O7LM8Ozgjv

[Pastel BioScience @PastelBio]

Mass spectrometry-based draft of the mouse proteome | https://t.co/NKsXc2PTsV #proteomics

[NorthOmics lab @NorthOmics]

Cover stories from NorthOmics lab

[Proteomics Resource Centre (PRC) @proteomics_core]

A 5-cent 100-ohm transistor saves our 2000 dollars Synology 37T NAS. This happens on mass spectrometers and HPLC boards a lot.

[Proteomics Resource Centre (PRC) @proteomics_core]

1.7 um resin in tip column, a bit high pressure though :)

[Proteomics Resource Centre (PRC) @proteomics_core]

Sample clean-up is extremely important for metaproteomics on stool samples. Otherwise, you will get a decent MS run with barely MS2 spectra identified. Don't be freaked out, these spectra might be just from the food debris, anything from the dishes.....

[NorthOmics lab @NorthOmics]

High throughput proteomics on 4 plates by robots, making life easier