Pablo 👨🏽‍💻

👨‍👩‍👧 Papá 💻 Developer 🎭 Improvisador en formación 🎙 Ignorancia Colectiva

[Pablo 👨🏽‍💻 @psbarrales]

En este cap de mi podcast habíamos predicho la inflación.
Esta aburrido un Domingo? Por qué no? Escúchalo acá: https://t.co/BviIcEDWOa

[Anthropic @AnthropicAI]

Many drugs work by binding to a specific target in the body and blocking or changing what it does. An important first step in the drug development process is designing a molecule that can bind tightly to its target. Traditionally, that's meant weeks or months of expert work per target, sifting through a large number of candidates to identify the few that work.

We wanted to test if Claude could successfully design novel protein binders from scratch (also called de novo design). With a protein design prompt written by a human expert, Claude autonomously designed protein binders against 14 out of 15 targets.

We then worked with Adaptyv Bio and Twist Bioscience, who independently built and tested the proteins Claude designed.

[Pablo 👨🏽‍💻 @psbarrales]

@cursor_ai You just did what? 🥹

[Cursor @cursor_ai]

We're making Git hosting more reliable, performant, and scalable.

This post traces 20 years of Git infrastructure and explains how that history led us to design and operate our Git storage, Origin, as if it were a database.

https://t.co/UW7jHuItSX

[Pablo 👨🏽‍💻 @psbarrales]

@denokennedy Espera a que seas Engineering Manager

[Pablo 👨🏽‍💻 @psbarrales]

@biobio Cuantas veces he visto la misma noticia

[Pablo 👨🏽‍💻 @psbarrales]

@bunjavascript Why 6 days, are you building linux?

[Pablo 👨🏽‍💻 @psbarrales]

@spoonkycat Hermes es muy util, le pides que se auto configure, que use otro arnés, puedes armar un chat grupal y pedir a todos a la vez algo y que se coordinen entre ellos. Hasta ahora el mejorcito a mi parecer

[Pablo 👨🏽‍💻 @psbarrales]

@maywrence

[Pablo 👨🏽‍💻 @psbarrales]

@biobio Provoca risa a *

[Pablo 👨🏽‍💻 @psbarrales]

@opencode

[Pablo 👨🏽‍💻 @psbarrales]

@unclebobmartin AGI

[Pablo 👨🏽‍💻 @psbarrales]

@caco_patane Que recuerdos, lanzar pm2 en una screen con nombre, ctrl a y ctrl d y me olvido

[Pablo 👨🏽‍💻 @psbarrales]

Se pueden bloquear las cuentas verificadas? Demasiado clickbait o ragebait para ganar interacciones

[Pablo 👨🏽‍💻 @psbarrales]

@AlertaNews24 Chile:

[chum1ng0/security research @chum1ng0]

🚨 🇨🇱 Mayor brecha de cadena de suministro de IA 2026: hackeo de LiteLLM impacta a miles de empresas en el mundo.

Posibles afectados en Chile:

Presidencia de Chile gob[.]cl

achs[.]cl

https://t.co/PEuDy2b1rF

#ciberseguridad #Chile #LiteLLM #IA

[Red de Emergencia ONG @reddeemergencia]

#Ciberseguridad

[Pablo 👨🏽‍💻 @psbarrales]

@alessiogarcai Si tiene ticker azul solo es bait

[Pablo 👨🏽‍💻 @psbarrales]

@lacuarta noticias de peos

[International Cyber Digest @IntCyberDigest]

‼️ BREAKING: An active npm supply chain attack has compromised at least 868 packages carrying over 2 billion monthly installs with a credential-stealing worm. Shai-Hulud is back.

It started with the compromise of the GitHub account of the maintainer behind keyv, a library with roughly 127 million weekly npm downloads.

A preinstall hook fires on npm install and drops a stealer that sweeps npm, GitHub, AWS, Kubernetes and Vault secrets, and then spreads to more maintainers.

[Pablo 👨🏽‍💻 @psbarrales]

@manodeyvin - Burlarse de PHP