Purnima Kovuri

Researcher exploring fundamental biology by day and embracing a zest for life by night.

[ISEB5LU @iseb51520]

Day 3 Oral presentations!!!! #ISEB5 Part1

[Purnima Kovuri @purnimakovuri]

"Entangled World of DNA Quadruplex Folds" highlights analysis on DNA quadruplex structures to identify 48 unique motifs based on loop connectivity. Research conducted during my time as a JRF at IIT Hyderabad. @MBL_IITH @ACSOmega
https://t.co/0To3rQKV6v

[SciencesNetwork @SciencesNetwork]

SCI-VCF: A cross-platform GUI solution to Summarise, Compare, Inspect, and Visualise the Variant Call Format
https://t.co/ocMAmP9kCz

[Purnima Kovuri @purnimakovuri]

Congratulations Dr. Viswa!

[Himanshu Sinha @Himanshu_IITM]

Yesterday, Dr. Viswa Chaithanya defended his thesis (online) and graduated from the Systems Biology Lab, @iitmbt and @IBSE_IITM. Congratulations, and wishing him continued success in his future endeavours.

[Himanshu Sinha @Himanshu_IITM]

India's groundbreaking innovation for pregnancy care: Garbhini-GA2

We've developed Garbhini-GA2, India's first ultrasound-based model for accurate 2nd and 3rd trimester fetal dating (gestational age). 1/n

[Himanshu Sinha @Himanshu_IITM]

@liti_nice Viswa Chaithanya, first graduate student from Systems Genetics Lab @iitmbt shows in this paper that a common variant in a pleiotropic gene MKT1 regulates multiple stress responses via Pbp1 and Puf3 dependent manner. (1/n)

[Visit Udupi @VisitUdupi]

Captain MV Pranjal - You will be in our hearts forever.

We honour your supreme sacrifice to our nation. Jai Hind 🇮🇳

Om Shanti !
May your soul attain Sadgati 🙏

[Tom Ellis @ProfTomEllis]

Singer weren’t joking when they said they’re releasing a small benchtop size liquid handling robot @SingerInst - we’ve got bigger microwaves in my lab

[Himanshu Sinha @Himanshu_IITM]

After organizing @rbc_dsai_iitm AI/ML Conclave in Healthcare in collaboration with @IBSE_IITM and @cerai_iitm at @iitmadras, in conversation with Vaitheeswaran from @NewIndianXpress. We discussed AI/ML healthcare projects being done at IBSE/RBCDSAI centers... 1/2

[Himanshu Sinha @Himanshu_IITM]

Venkatesh @IBSE_IITM @rbc_dsai_iitm has developed this offline & online interface allowing everyone to visualise & compare variants in VCF files. Using GUI one can visualise variant distribution across chromosomes. The tool doesn’t need any coding expertise & is freely available.

[Purnima Kovuri @purnimakovuri]

Happy to share our review on phenotypic plasticity in yeast! Exciting insights on genetic architecture & the interplay of gene-environment interactions in driving adaptation.
https://t.co/TwVNWfxsqa
@Himanshu_IITM @Anupama__Y @TrendsGenetics @IBSE_IITM

[Himanshu Sinha @Himanshu_IITM]

Genetic architecture of phenotypic plasticity can be determined using the #yeast model. In this @TrendsGenetics review, we describe how single gene deletion, SGA and QTL studies inform us about additive & epistatic architecture (1/3) https://t.co/jiPqPrOpWH

[Trends in Genetics @TrendsGenetics]

Role of genetic architecture in phenotypic plasticity https://t.co/PHUdO5EUhU

[Andrew Akbashev @Andrew_Akbashev]

No reward - no duties.  75% of respondents have reduced the hours spent on academic duties since 2020 (Nature polls).

Mostly due to burnout and unwillingness to work for free.

This included attending conferences, peer reviewing manuscripts and grant proposals, committees, mentoring and even teaching.

Why?

Because scientists are tired of not being able to do #science.

- Students are tired of being unappreciated and overloaded

- Faculties are tired of “community duties” that become overwhelming (conferences, committees, reviewing, outreach, etc)

And everyone is tired of small salaries, zero empathy and little credit.

The problem is greatly summarized by Isabel Müller (in the article):

“There’s so little acknowledgement that people have difficult, complicated lives outside of work.”

A year ago, Nature described how PhD students don’t want to be postdocs and faculties are leaving academia. Now, we see that those who stayed are trying to resist the system from the inside.

But the problem is - the system is too rigid, too traditional and too elitist.

So, as a community, we can change it only by raising our voices and expressing distaste with the status quo. I applaud Nature for writing about these issues so regularly. The academic world has too many interdependent parts which should be addressed concurrently.

This is why we should stay united and strong as a community.

Regarding the academic environment we all hope to have, I loved how Isabel Müller put it in the article:

- I hope it becomes the new normal to say: “My life matters. My work is an important part, but I decide what my life looks like, not my employer”.

#AcademicTwitter #education

[Purnima Kovuri @purnimakovuri]

Wrote a 15 page long report.
Now I'm literary drained

[Purnima Kovuri @purnimakovuri]

Coffee is elixir

[François Chollet @fchollet]

We owe so much to the people who invented coffee

[Chennai Weather-Raja @chennaiweather]

When you say Chennai weather is cold to many people they will make fun of you.

I would say, It is relatively cold...

Went to the UK a few years back in June(summer) and at 27 degrees Celsius, they felt very hot. What to say?

[Ming "Tommy" Tang @tangming2005]

5 websites for drawing scientific figures: 👇 🧵

[Lydicious @Lydiacious]

Great afternoon in Heidelberg. Hiking, taking pictures, talking and drinking the sweetest wine I ever had: Federweißer! Energized for the next #EMBOEvoEco Session! @sonal_nd @purnimakovuri @lj_mihajlovic , Heidi, Benjamin and John