Andrew Balmer

Senior Data Scientist @sangerinstitute | Antimicrobial resistance evolution | Researcher and coffee drinker

[Andrew Balmer @Quackscience]

Most AMR data is still collapsed to “resistant vs susceptible.”

But resistance often shows gradual shifts before cut-offs.

AMR Cartography maps full profiles in 2D — revealing co-resistance, sub-breakpoint changes & lineage patterns.

🔗 https://t.co/kSi5JM5K1u

[Andrew Balmer @Quackscience]

🚨 New paper in eLife!

We analysed >100k malaria parasite samples to track the rise of artemisinin resistance.

Resistance is now emerging in Africa, echoing SE Asia 10–15 yrs ago.

Genomic surveillance is key to staying one step ahead!

https://t.co/lNW4D9TJws

[Andrew Balmer @Quackscience]

The framework works across species & drug classes — and the code is open-source. Would love feedback from anyone working in AMR surveillance!
Preprint: https://t.co/kSi5JM5K1u

[Andrew Balmer @Quackscience]

New Preprint! 🚨:

Most AMR data gets collapsed into “resistant” vs “susceptible.”

But resistance isn’t a simple switch — it changes gradually, and often in correlated ways across drugs.

[Andrew Balmer @Quackscience]

Applied to 3,600+ pneumococcal isolates, AMR Cartography revealed lineage-specific resistance and the genetic changes driving multidrug resistance.

[GlobalPneumoSeq @pneumowatch]

[New pre-print🚨] When a single genotype (pbp) confer resistance to multiple antibiotics (penicillin and cephalosporins), how do we make sense of genetic changes and their impact on AMR?

A new concept - AMR cartography is invented by @Quackscience

https://t.co/8UWQNdHgUr

[Andrew Balmer @Quackscience]

We’ve just posted AMR Cartography on bioRxiv: a way to study multivariate drug resistance and connect it to genotypes. Would love feedback from people working with surveillance MIC data! @AntibioticResis @crypticproject
https://t.co/kSi5JM5K1u

[Andrew Balmer @Quackscience]

Just posted our new preprint:
Antimicrobial Resistance Cartography – A generalisable framework for studying multivariate drug resistance @CamInfectDis @CambridgeDDU

https://t.co/kSi5JM5cbW

[Andrew Balmer @Quackscience]

AMR Cartography lets us visualise how different pneumococcal lineages have distinct multivariate resistance phenotypes. @pneumowatch

[Andrew Balmer @Quackscience]

New preprint: Antimicrobial Resistance Cartography — a simple way to map multivariate drug-resistance phenotypes, using data from @CDCgov.

https://t.co/kSi5JM5K1u

[bioRxiv Genomics @biorxiv_genomic]

Antimicrobial Resistance Cartography: A Generalisable Framework for Studying Multivariate Drug Resistance https://t.co/0O2LKGALoC #biorxiv_genomic

[Lucy Weinert @Lucy_Weinert]

Introducing AMR cartography - brilliant work by @Quackscience

[MalariaGEN @malariagenomics]

Announcing the latest version of MalariaGEN’s world-leading malaria parasite data resource: Pf8! 📢

In this release, you’ll find:
🦠 33,325 parasite whole genomes
🌍 Samples from 122 different locations
🗓️ 56 years of data

Read more:
https://t.co/Yw87gyhyXL

[MalariaGEN @malariagenomics]

Our next Journal Club will be all about the new Pf8 data release!

Join Dr Nina White, Senior Data Scientist at the Genomic Surveillance Unit (@sangerinstitute) to learn to make the most of this unique malaria parasite data resource.

📅July 22, 1:30pm

https://t.co/P93ItRCcUm

[@EPPIcenter at UCSF @EPPIcenter_UCSF]

morning coffee and @Quackscience
Global Spread of Artemisinin Resistance: Insights from over 100K P falciparum Samples
Thx @MESAmalaria @ChatWithChauke @ninawaleEEB @eselimnl @cl32_sanger @RichardDPearson @ingeneswetrust @cristina_ariani
https://t.co/ppHSNOteC0

[ASTMH @ASTMH]

Egypt declared malaria-free after 100-year effort, BBC reports. https://t.co/Nvy0EYFAp5

[MalariaGEN @malariagenomics]

Our October Journal Club is all about drug-resistant #malaria parasites💊

Dr Andrew Balmer will delve into a recent review that maps data from 112,000+ P. falciparum genome sequences worldwide to track kelch13 mutations: https://t.co/nuK0m9zMSN

Register: https://t.co/iOiNWbLNYE