Today I was part of the thesis defense committee for Gabriel ! He presented his work on the effects of statins on Zika virus infection and toxicity in human neurons and microglia. Congratulations, Gabriel, Special thanks to his advisor Dr. Kelly Magalhães and LIMI lab!
Study in Brazil with 21 patients found 9 rare genetic variants in immune-related genes (IL17RC, IFNA10, NLRP12) linked to MIS-C.
Mutant NLRP12 weakened NF-κB inhibition.
More research needed for diverse groups.
https://t.co/7KoYPnEXsl
Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis) - Journal of Biological Chemistry https://t.co/C6xbQszlbL
Download our extended database of postdoc fellowships.
276 funding opportunities. For each entry, we provide eligibility/requirements, amount, deadline, link, description, etc.
Download our database here: https://t.co/EbTahdzbkp
Accompanying commentary today
The story of the skull marrow bone channels and their role in building an immune system for the brain
@ImmunityCP@jonykipnis@JasminHerz1
https://t.co/7HAUSPClDZ
A team of Brazilian doctors are using earwax to detect tumors with 100% accuracy. Earwax is lipid soluble and has a lower turnover rate than other biological fluids like blood, urine, sweat and tears—making it ideal for detecting longer term changes in metabolism.
The team hopes this new method will replace less accurate, more expensive methods like blood labs and urine tests.
Today I had the honor of presenting at the Frederic S. Fay Memorial Symposium at UMass Chan Medical School.
It was an incredible experience to share my research among so many inspiring scientists and to attend the keynote lecture by Dr. Andrew Gewirtz!
Maintenance of chronic neuroinflammation in multiple sclerosis via interferon signaling and CD8 T cell-mediated cytotoxicity https://t.co/NOnTcwUAGp #biorxiv_immuno
Sooo happy to finally have this one published!! (3 years in the making… 👀) A comprehensive investigation into the recency and geographical origins of both SARS-CoVs that spilled to humans in the past few decades, now in @CellCellPress https://t.co/4qnUpPNuEn
Eczema, dermatitis, and acne aren't skin conditions.
They're gut disorders manifesting on your skin.
Steroids and creams always fail long-term because the root cause is in your GUT.
Here are 16 evidence-based tips to fix it: 🧵
1) Stop eating sugar
Habemus Papam! We have a Pope!
The Cardinals gathered in the Vatican’s Sistine Chapel have elected Cardinal Robert Francis Prevost as the 267th Pope, who took the name Pope Leo XIV.
A single mitochondrial DNA mutation in mice causes autism-like behavior—social deficits, anxiety, and EEG disruptions—with no changes to brain anatomy.
Let’s break it down 🧵1/10