Science Me

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[Massimo @Rainmaker1973]

Scientists have created one of the most detailed 3D reconstructions of a human cell (eukaryotic cell) ever produced.

This groundbreaking model, often termed a "Cellular Landscape Cross-Section Through a Eukaryotic Cell," combines data from X-ray tomography, nuclear magnetic resonance (NMR), and cryo-electron microscopy to map molecular structures in extreme detail.

[Brian Roemmele @BrianRoemmele]

Decoding Morse Code.

[Massimo @Rainmaker1973]

Researchers from Spain and China achieved a significant advance in Alzheimer’s research by developing nanoparticles that clear toxic brain plaque, a key contributor to the disease, and reverse memory loss in mice.

Published in Signal Transduction and Targeted Therapy, the study showed that three injections of these nanoparticles reduced harmful amyloid beta proteins in the brain by up to 60% within an hour.Remarkably, mice with severe memory and cognitive impairments regained normal behavior within six months.

The treatment not only cleared brain plaque but also repaired the blood-brain barrier (BBB), which protects the brain and clears waste but becomes impaired in Alzheimer’s, allowing harmful substances to accumulate.

Acting as a “supramolecular drug,” the nanoparticles restore the brain’s natural waste-clearing system by activating the LRP1 protein. This improved blood flow, reduced inflammation, and supported brain healing. While still in animal testing, this approach suggests a new path for Alzheimer’s treatment, focusing on enhancing the body’s defenses rather than just targeting toxic proteins.

If successful in humans, it could transform the fight against Alzheimer’s and other neurodegenerative diseases.

[Science Me @realscienceme]

The four canons of science. More at https://t.co/ssyeJSW9x9

[Science Me @realscienceme]

Could The Last of Us Really Happen? https://t.co/zkGfFoSm6q

[Joscha Bach @Plinz]

The next stage of evolutionary complexity after mammals would probably have been (hermaphroditic but multimorphic) exowombists, where individuals can lay a seed that grows into an arbitrarily large sessile womb organism requiring external feeding, and others fertilize it.

[Science Me @realscienceme]

@Culture_Crit Guess the island

[Science Me @realscienceme]

@iamjohnoliver Come to New Zealand J. Oh! No liver!??

[Aleksandr Volodarsky @volodarik]

Sunday read.

This is hilarious. Engineers are competing who creates the worst UI on Reddit.

I think the winners are:

1/ Enter your phone number

[Science Me @realscienceme]

@InternetH0F This is the horror movie It Follows but without the $10mil. Or the snail. But something in there is exactly this.

[Science Me @realscienceme]

@raven_azrael @SteveStuWill I looked it up, it’s 106:1

[Science Me @realscienceme]

@raven_azrael @SteveStuWill It’s off the chart which only goes up to 14:1 (f:m).

[Science Me @realscienceme]

The AI takeover becomes way more palatable if they’re all like these 1 foot tall munchkins.

[Smoke-away @SmokeAwayyy]

Look how quickly this little DeepMind robot gets back up after being knocked down 👀

[Science Me @realscienceme]

@StreetProfessa @Matthew42813766 @Aella_Girl

[Science Me @realscienceme]

How Gene Therapy Actually Works
https://t.co/JUyS8SEeok

[Science Me @realscienceme]

@Aella_Girl Did you inadvertently turn a survey on yourself??

[Curiosity @CuriosityonX]

Clearest image ever taken of Mars' Moon Phobos.

[Science Me @realscienceme]

@abacaj @Plinz Is this even real? It was published *9 days* before the Wright brothers flew the first powered airplane on December 17, 1903.

[Science Me @realscienceme]

@hendrycks @ylecun Why can't we focus AI on creating its own alignment training material and then have it study that?