🦓RAre mimics🎭

2k+nutshell case rprts: #Rheumatoid #Arthritis'/chron #polyarthritis' - sheer infinite DDx, long&thin tailed:

[🦓RAre mimics🎭 @reinmd77]

10yr f/up: 435 sero-RA:
10% confirmed RA, others reclassified, revealing significant heterogeneity in the diagnosis of seronegative RA
https://t.co/UhgmLxh1rH

[🦓RAre mimics🎭 @reinmd77]

37yo♂️20yrs nodul tumoral calcinosis ⬆️⬇️ flare
🆕3wks ubiquitous⚡⚡fatigue
ROS✔️
ESR80 CRP17
?flare
🔑 palm lesion🚫⚡
🔑Trunc rash 6mths ago
RPR+ Trepo pallid+
◾Syphilis
(Hickum's!/🚫🪒)
https://t.co/PiUWS1k1lY

[Dr. John Cush @RheumNow]

CAR-T Reality Check!
The hype is outrunning the evidence, which now lives in a handy dashboard created and presented by Dr. Mike Putman @EBRheum. There are almost as many studies as there are CAR-T treated patients. Few numbers, limited F/U - Yet everyone is gaga about CAR-T.
https://t.co/PUAovqtXMr

[🦓RAre mimics🎭 @reinmd77]

16yo♂️poly⚡
"JIA"
FHx sibling simil
IFX 7yrs?
no -itis, deformity
⚗️⚗️✔️
📸🎞️
🪒
Urinary glycosaminoglycan: MPS
🧬GALNS
◾Morquio syndr
https://t.co/D3GYyHLCAs

[🦓RAre mimics🎭 @reinmd77]

52yo♂️2mths⚡jts
ESR41CRP7ACPA33.RFANA✔️
MTX HCQ
🆕5days🤒black spots eyes hair⬇️oral ulcers rash
eye investigat++"white dot syndr?"
➡️Pred, eyes worse
++++ophtalm: vasculitis ⚗️⚗️⚗️
🆕VDRL/RPR TPHA/FTA Abs➕
◾Ocular syphilis w/reactive arthritis
💊😄⚗️✔️
https://t.co/1Phfw3UKQp

[Eric Topol @EricTopol]

We've got significant safety and security issues with generative AI healthcare that need to be addressed @jnkath @JClusmann @Nature https://t.co/iH3uj8wB3P

[🦓RAre mimics🎭 @reinmd77]

34yo♀️6mths⚡⚡knees weightbear🚫
red shiny knees tender quads⬇️ ROM ⬇️
ROS✔️
⚗️ ESR85 CRP6
🎞️🎞️
🔑🔑Post partal, twins
◾Transient Osteoporosis Knees w/ Pregnancy
Calcitonin D NSAID
1mth: VAS10➡️2
1yr😄
https://t.co/iWvis6SdMu

[🦓RAre mimics🎭 @reinmd77]

24yo♂️10yrs📈 thickening skin
ROS✔️
IGF-1, thyroid function, RF✔️
📸🎞️
Primary hypertrophic osteoarthropathy-PHO
https://t.co/8pddcYB03U
Details 💰🧱

[🦓RAre mimics🎭 @reinmd77]

42yo♂️mths⚡swellg elbow
CRP22
🎞️soft tissue+"PMR" Pred
CXR! BAL: MSSA 💊
CT〰️
🆕papules macules
🆕 Polyarthritis
🆕Gluteal absc
🔑⬇️⬇️Ig
🧬BTK splice-site variant
◾Atyp X-linked agammaglobulinemia
IgRT🙂
https://t.co/j3Xi5mY2Wo

[🦓RAre mimics🎭 @reinmd77]

51yo♂️1yr📈nodules hand, digits foot.
🚫⚡
ROS✔️✔️
⚗️⚗️🧫✔️
🎞️🎞️✔️
🔬non-caseat granulomas, epithelioid histiocytes multinucleated giant cells w/ scant lymphocytic cuffs
◾Darier‐Roussy Sarcoidosis Mimicking Rheumatoid Nodule
Pred 3mths😄
https://t.co/eTu7UhHkNW

[🦓RAre mimics🎭 @reinmd77]

Number two in all-time views

[🦓RAre mimics🎭 @reinmd77]

88yo♀️many yrs seroneg RA
MTX 🚫
Exam ++bilat -itis ubiquitous
ESR 82 CRP 5
🎞️No RA,
🔬intracellular calcium pyrophosphate crystals
◾Pseudo-rheumatoid arthritis
💊Pred, colchicine😀
https://t.co/QUgbiaEypA

[🦓RAre mimics🎭 @reinmd77]

All time favourite tweet according to views.

[🦓RAre mimics🎭 @reinmd77]

40yo♂️diffuse arthralgia widespread.
++⚡Hand edema, pitting
🎞️!
🔑Voriconazole /transplant liver& kidney
◾Voriconazole-Induced Periostitis
💊🛑:2 days later😀
https://t.co/uoDB7IOygh

[🦓RAre mimics🎭 @reinmd77]

45yo♂️9mths📈⚡swellg⬇️ ROM wrist
⚗️-pic
🎞️🎞️
🧫✔️
🔬Plasmacells infiltrates, crystalline inclusions
🎞️Whole body✔️
◾Solitary Bone Plasmacytoma
☢️4wks
F/Up🙂
https://t.co/HV4PFrdNy6

[🦓RAre mimics🎭 @reinmd77]

16yo♂️1yr📈“swellg”nails
➡️Pic
ROS✔️
⚗️✔️
CXR✔️
🎞️!
◾incomplete pachydermoperiostosis (primary hypertrophic osteoarthropathy)

https://t.co/MgeggCohMK

[🦓RAre mimics🎭 @reinmd77]

18yo♂️⬇️⬇️ROM(+)⚡
Age3 12:ubiqu swellg⬇️ROM
⚗️✔️✔️ "JIA"
age11🔬synov++ 🚫inflam
🎞️++effus cyst bones,🚫erosiv
ia,MTX TNFs ABA TOC ANA TOF〰️
🪒!
🧬PRG4
◾camptodactyly-arthropathy-coxa vara-pericarditis syndr CACP
https://t.co/lo3vlGJ8xn

[🦓RAre mimics🎭 @reinmd77]

10yo♂️15mths recurr ⚡knee swelling
⬇️ROM
🎞️🎞️
🔬synovial arteriovenous malform
◾Intra-articular synovial arteriovenous malformation
https://t.co/6VzUgZSyRa

[🦓RAre mimics🎭 @reinmd77]

36yo♂️1yr sym polyarthritis
ESR⬆️
"polyclo γglob⬆️ACE⬆️ ANA⬆️ RF37
🔑2yrs recurr leg ulcers violaceous halos nodules."Syph" Penicill
lupus pernio?
🔬foamy histiocytes acid-fast bacilli: M. leprae.
◾Lepromatous leprosy
💊😄
in Portugal❗
https://t.co/hTYSz7JqLs(A,RF%20(8IU/mL)

[🦓RAre mimics🎭 @reinmd77]

19yo♀️3yrs episod🤒⚡swellg
ESR⬆️Hb⬇️Amyloid⬆️
slight B-cell impair
🎞️effus hips knee ankle
facial dysmorph spars hair slender
Age10 chron sinusi recur pneumo bronchiect:prim ciliary dyskines PCD🧬
Occam🪒TRNT1🧬
◾TRNT1 relat autoinflam syndr w/PCD
ETN😄
https://t.co/aNxZeit0TG

[🦓RAre mimics🎭 @reinmd77]

26yo♀️⚡crepitat hands feet knees
⚗️✔️
Scolios Hypermob Marfanoid camptodact
🎞️
🔑mediofacial ⬇️plasia ocular proptosis nasal bridge⬇️macrognathia ⬇️ hearg myop
FHx⚡⬇️ hearg opthalm issues
🧬COL2A1
◾Stickler syndr
https://t.co/qIiXypkDv4

[🦓RAre mimics🎭 @reinmd77]

RAre mimic
63yo♀️>40yrs large&small jts pain -inflammatory type
X-ray Atypical destruct changes
Clue FHx vy early/pediatric OA
Proof mutat COL11A2

Dx adult Stickler syndr III
https://t.co/SQwEJ1Umed

[🦓RAre mimics🎭 @reinmd77]

51yo♀️⚡polyarthritis nodul
"EN": Pred MTX Colch🚫
ESR CRP ⬆️
🎞️❗
🔑?BRCA+ BC×4yr
BC mets? GATA3🚫 trypsin✔️
⚗️lipase📈📈
Oncology Rx〰️
⬆️⚡⬇️AdL
GI sx(+)🎞️
🔑🔬Pancr npl
Occam's PPP
🔪 pancreas
◾Pancreatitis, panniculitis, polyarthritis syndr— paraneo
https://t.co/aGgMgioRc6