I guess venture Road is a bit like Queens in the tennis world, a precursor to the big event. Wimbledon is not for us, but San Diego on the 22nd of June most certainly is. It could be a fasten seatbelt moment.
The market knows AVA6000 data is scheduled to be released in the next 6 weeks, plus AVA6103 continues adding time served, so I don't think #AVCT is finished here.
Avacta is now the most exciting small Pharma ever in my view because it is not developing a new drug, it is developing an exciting delivery platform that can deliver many drugs much more safely and effectively. Many of which are about to become off patent. Remarkable!
#AVCT Big plans for AVA6103. Potentially 7 expansion cohorts. Some new indications added (see recent interview)
I wonder what changed between February and April
Expansion cohorts are planned in additional FAP+ cancers including hormone-receptor positive breast cancer (HR-BC), non-small cell lung cancer (NSCLC) and colorectal cancer (CRC)”
@Keir_Starmer why hasn’t MI6 been informed on the Mandleson DV being rejected. It must surely be of vital interest to them? If they did know, how can it be that you didn’t know?
@Keir_Starmer why hasn’t MI6 been informed on the Mandleson DV being rejected. It must surely be of vital interest to them? If they did know, how can it be that you didn’t know?
This is the most defining interview with Avacta ever held. No ifs no buts. Powerful chemo delivered straight into the tumour then controlled release up to period of 5 days! The age of powerful chemo without the side effects! The next few months could be game-changing.
New #RxforBiotech podcast episode with @coughlin582, CEO of @avacta. See how the company's approach to cancer treatment using targeted chemotherapy could transform #cancer care.
https://t.co/DM51xOxjDP
@KemiBadenoch@Conservatives As a lifetime, conservative voter and author of: The Nemesis of Planet A - Is The Human Race Sleepwalking Towards Its Own Extinction? I am now unable to vote Conservative because of your net zero stance. It is an existential issue where a narrow national view must not prevail.
Chris and her brilliant team continue to build and protect the IP of #AVCT in order to exploit the full value of preCISION for shareholders. honoured to sit on the board of such a disruptive biotech. 2026 will be a transformational year for us all 💥
Myles makes some powerful points here. In my opinion Avacta is one of the most under the radar investment opportunities that are out there. One only has to visit their website and watch the videos to understand this..
For @avacta #AVCT shareholders, the low revenue figure for $KYMR is important to highlight here.
I believe that the UK market severely underestimates the valuations that the US investment community ascribes to early-stage-revenue or even pre-revenue companies, that have promising therapeutics in the clinic.
There are currently 133 biotech companies listed on NASDAQ with revenue of less than $100m, but with mkt caps higher than Avacta's ($456m). [And those companies that are recording any revenue in their P&Ls, are generating it from licensing deals and/or grants. That is to say, almost all of those 133 companies don't have an actual approved product on market).]
Global revenue from drug sales was around the $1.65 trillion mark in 2024. Estimates vary, but the median estimate (out of the ones I've found, at least) for global oncology sales last year was $252bn, or $15-16% of all drug sales worldwide. Oncology accounted for the largest slice of the pie, ahead of all other major therapy areas such as immunology / autoimmune, cardiovascular, CNS / mental health, diabetes / obesity, etc.
The Avacta bull thesis is that pre|CISION PDCs come to dominate the global oncology market over the next two decades, not only largely displacing both conventional chemotherapy and novel ADC sales, but also reducing the demand for immunotherapies and other biologics.
Ergo... Avacta's ultimate total addressable market is likely to be larger than all of those 133 NASDAQ-listed pre-product biotechs, which currently command higher mkt caps than Avacta.
It's going to take an almighty upset in the clinic for Avacta not to rerate incredibly powerfully over the coming months and years.
[All IMO, DYOR, etc.!]
The planet continues to warm faster than anyone predicted. We are heading to frightening times without effective global leadership. https://t.co/F2UW1QyY8J
https://t.co/Fl5JELq7Rc