Aina Rill

PhD at Cellular Systems Genomics Group-@CarrerasIJC.
Interested in #Cancer and #Immunology through #Singlecell🧬💻

[Aina Rill @rill_aina]

PhD✅

[Josep Carreras Leukaemia Research Institute (IJC) @CarrerasIJC]

Another thesis successfully defended 👏

Congratulations to Aina Rill (@eli_mereu's lab) with her work on "Mapping Inflammation and T cell Dynamics with Single-Cell Genomics" 🧬💻

Well done, new doctor!👩‍🔬🎓

[KelvinTuong @KelvinTuong]

We have now written up a preprint on this!

https://t.co/QY6Ut09qii @theHumanBorch

[Eduard Porta @eportacangen]

It took 3 years, 4 rounds of reviews, 96 VISIUM samples, 10 cancer types, and 1 clinical trial, but it's finally out:

The spatial landscape of Cancer Hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity

Here's what's new 👇

https://t.co/WMCyTWhVOX

[Aina Rill @rill_aina]

@MolOncology @CarrerasIJC Honored! Thank you so much!! ☺️

[Molecular Oncology @MolOncology]

🏆Congratulations to @rill_aina for winning a Molecular Oncology prize at the 2024 @CarrerasIJC Symposium, with her poster "Integrative single-cell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunotherapy response in B-cell neoplasias"👏

[Aina Rill @rill_aina]

Very honored to have received one of the Molecular Oncology Poster Session Awards last week from #IJCSymposium “Updates on Genetics and Epigenetics of Haematological Malignancies: From Knowledge to Applications” at @CarrerasIJC ✨

[KelvinTuong @KelvinTuong]

So i'm very happy to say that my very talented honours student has reimplemented the entire trajectory workflow in R, intersecting with @theHumanBorch's scRepetoire! Code is now live https://t.co/DUHdzq0V7P but lacking vignette; will be up shortly!)

[Ugur Uslu @UgiUslu]

Published today @NatureBiotech: @CarlHJune and I reveal how CAR T cells are finally tackling solid tumors!
@PennPPA @PennMDForum

https://t.co/wJkfMfVxgC

[Aina Rill @rill_aina]

@PauBadiaM @NatureNeuro @Cels121 Congrats to you both!! Amazing work✨

[Aina Rill @rill_aina]

Check out how we found intrinsic factors of CAR-T cells that may play a major role on its clinical success by single-cel multiomics!! 🧬💻💖
Paper available in Cell Reports Medicine:
https://t.co/zoo9DEZwQb

[Aina Rill @rill_aina]

My first first-author paper is out!! Check out this incredible science done in collaboration with @MerGuMu and @Menendez_Lab @eli_mereu 🧬🧫💻💖

[Josep Carreras Leukaemia Research Institute (IJC) @CarrerasIJC]

🚨Researchers from the @Menendez_Lab and @eli_mereu Lab, @MerGuMu @trincadojl @rill_aina describe at @CellRepMed the molecular features making a CAR-T cells infusion successful 💪

Read the news piece at 👇
https://t.co/ozZZg3K79X

Results show objective features in the infusion product may predict future therapeutic success, advocating for a more precise quality control.
Also, characteristics of the CAR-T expansion within the patient are related to efficacy and could be used as early warning.

Thanks to funders 🫶 @contracancerINV @FundlaCaixa @unoentrecienmil @fcarreras

[Elisabetta Mereu 🇺🇦 @eli_mereu]

🚀 New research alert! Dive into the single-cell multi-omics of CD19-CAR+ and CAR- T cells! A promising step in #CARTcell therapy for better outcomes! Led by @MerGuMu, @rill_aina & @trincadojl from @Menendez_Lab and my lab! Enjoy! https://t.co/O1yfWBAfoE

[Holger Heyn @hoheyn]

STAMP is OUT!

Sequencing-free #singlecell RNA and Protein profiling.

Game-changing approach for scalable and cost-efficient analysis of single cells.

The future starts today!

Amazing ⁦@LGMartelotto⁩ ⁦@DrJasPlummer⁩
https://t.co/tgsIvTtpBo

[Aina Rill @rill_aina]

@eli_mereu 💪💪💪

[Josep Carreras Leukaemia Research Institute (IJC) @CarrerasIJC]

Brilliant �� #YoungResearchers Seminar yesterday with Aina Rill, from @eli_mereu’s lab!

We have learnt more about her project "Integrative #SingleCell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunotherapy response in B-cell neoplasias". Great work! 👏

[Elisabetta Mereu 🇺🇦 @eli_mereu]

📢Our lab at the @CarrerasIJC is looking for candidates for the competitive PhD INPhINIT incoming fellowship from La Caixa Foundation. We work on the application of #singlecell genomics and ML to improve cell-based immunotherapy in Myeloma and others B-cell neoplasms. Plz RT!🔁

[Mo Lotfollahi @mo_lotfollahi]

Our multimodal model to combine TCR sequences with scRNA-seq is finally out. The most interesting part for me was observing a clear case where the combination of TCR sequence and cell state (RNA) preserved both clonotype and cell type information, leading to a more holistic cell representation that captures phenotype and functionality. We also decompose the contribution and importance of each modality. This was a really fun project spearheaded by @DrostFelix, whose amazing perseverance during a long review period, and collaboration with @schubert_benni and other fantastic collaborators, made it possible.

Read the paper :https://t.co/UtrYcb5EyY

[Aina Rill @rill_aina]

@AlejoFraticelli Thanks!! 🧬💪🏼🥰

[Aina Rill @rill_aina]

Enjoying the ISCO’24 conference at Barcelona and presenting our work in Alcoholic Liver Disease🧬

[Dr Javier Sánchez Utgés @javierutges.bsky.social @JavierUtges]

Really glad to see our work published in @Nature @CommsBio: https://t.co/46XqPNW5yi.
This analysis of 39 fragment screening experiments sets the scene for our future work on function prediction for ligand sites across the @PDBeurope. @gjbarton @bartongrp @stuartmac44 @CallumMIves