Rakesh

Oncopathologist, @MAHE_Manipal

[Rakesh @RK_Path]

Amoebic Colitis
#pathology #GIpath

[Charlie Herndon @DrCycloPath]

#PathQuiz 🔬🧬 #GynPath

A) Endometrioid Adenocarcinoma
B) Mesonephric-like Adenocarcinoma
C) Clear Cell Adenocarcinoma
D) High-grade Serous Carcinoma

#Pathology #GynPath

[Siba El Hussein, MD @SibaElHussein]

Splenic marginal zone lymphoma➡️look for these 2 zones:

🩸Central zone of small lymphocytes replacing reactive germinal centers

🩸Peripheral zone of small/medium-sized cells with abundant pale cytoplasm, resembling marginal zone cells

#hemepath #lymsm #PathTwitter #MedTwitter

[Janira Navarro @Janiranavarro]

Do we have to grade medullary thyroid carcinomas? Yes.

If there is tumor necrosis, ≥5 mitoses per 2 mm², or ≥5% Ki-67 labeling index, classify the tumor as high-grade MTC.

What constitutes necrosis? See pic 2

Dr. Nishino - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX #PathTwitter

[Janira Navarro @Janiranavarro]

Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP)

Allows <1% true papillae

True papillae: branching/arborizing structure lined by cells with nuclear atypia and containing fibrovascular cores (see pic 1)

Not true papillae (see pic 2):
- Transected follicle walls
- Sanderson polster

Dr. Nishino - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX #PathTwitter

[Janira Navarro @Janiranavarro]

Thyroid neoplasms - Helpful IHC table

Dr. Nishino - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX

[Mukul Vij, MD 🇮🇳 @vij_mukul]

#liverpath The #nutmeg liver Macroscopic demonstration of Budd–Chiari syndrome due to IVC leiomyosarcoma and a great teaching image for liver pathology

[Runjan Chetty @RunjanChetty]

This is a MALE patient with a solitary nodule on CXR

[Pranav Patwardhan @pranavp01]

How do we use and interpret immunohistochemical stains in lymph node evaluations in hematopathology? Here is a summary table I prepared which I hope will be useful, especially for beginners! #PathEd #MedEd

[Mark Ong @DrMarkOng]

Organ and diagnosis?

Colleague's case. Easier with a history, of course.

#pathology #PathTwitter

[ARP Press @ARP_Press]

Another papillary thyroid carcinoma (PTC) subtype:
Columnar cell PTC (0.2% of PTCs) is characterized by columnar cells with prominent nuclear pseudostratification. The pseudostratification and lack of abundant eosinophilic cytoplasm can help distinguish from the tall cell variant (see our last post).
#EndoPath #ENTPath #HNPath

[Janira Navarro @Janiranavarro]

Ovary-Endometrioid carcinoma

Diverse morphologic features (pic 1)
Endometrioid carcinoma with sex-cord pattern: Usually present presents with adenofibroma-like morphology
Not infrequently they have and aberrant IHC pattern like PAX-8 negativity and CDX2 positivity

Dr. Pilkington- Masters of Disguise: A Selection of Morphological Mimics in Gynae Tumour Pathology #ISGyP #Gynpath #pathology #PathX

[Mark Ong @DrMarkOng]

Bone marrow from elderly adult with end-stage renal failure.

Peri-trabecular fibrosis. Numerous osteoblasts, occasional osteoclasts. Dips in the bony trabeculae indicate bone resoprtion, but at the same time, abundant new bone formation (= woven rather than lamellar bone).

[Elizabeth Montgomery, MD @LizMontgomeryMD]

This week, I learned not only that gangliocytic paragangliomas were reclassified by the WHO as composite gangliocytoma/neuroma and neuroendocrine tumor (CoGNET) - thank you Rhonda Yantiss - but also that they can express CD117/KIT to result in wrong diagnoses on small biopsies.

[Charlie Herndon @DrCycloPath]

FNA from a 75-year-old's 3.2 cm peripheral lung mass. What is your impression?
A) Benign
B) Malignant
C) I need a higher power 🖼️
#CytoPath #PathTwitter #Pathology

[Sam Khader, MD @SamKhader]

Reserve cells are immature epithelial cells residing underneath the columnar pulmonary cells as depicted in this sketch by @SaeedAsiry. Reserve cell hyperplasia can mimick small cell carcinoma (hyperchromatic nuclei with molding), but the cells are very small with no necrosis.

[Innovative Science Press @science_press]

This is a crazy case of bladder cytitis cystica et glandularis with extensive intestinal metaplasia and low-grade dysplasia. It resembles a colorectal adenoma! There is lots to learn in Dr. Alex Kryvenko's new book. Get yours at https://t.co/11aBMJXEmQ #UMiamiPath

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Unusual case - Colonic glomus tumor !

[Anupama Arya @AnupamaArya12]

50/F 5cm lung mass.Patient has an ontological history. #cytopath #pathtwitter #lung @pepeheffernan @vi_monappa @kriyer68 @DrGeeONE @kr_abhisek

[Diane Brackett, MD @dgbrackett]

Fallopian tubes with nodular mesothelial/histiocytic hyperplasia - a benign, incidental finding
Good to know about all these incidentalomas so you don't mistake them for something else (also to not waste resources on unnecessary IHC)
#pathtwitter #gynpath #generalpath #pathoutpic

[Jasmine Vickery @VickeryJasmine]

Got a very interesting HER2 Immunohistochemistry to interpret today! What would you call it? #breastpath #breastcancer #her2 #pathX #PathTwitter #pathologists