Robert Mahar

Research biostatistician @unimelb @MCRI_for_kids @vicbiostat @austrim_cre | Interested in Bayesian decision making and adaptive trial design

[Robert Mahar @robertkmahar]

Consider #clinicaltrials randomising participants to prophylaxis and, upon failure, randomising to treatment. Can the randomisation be adaptively weighted in favor of the optimal interventions? 🧵@Katherine_J_Lee @bibhas1002 @asalim_hint @julieASimpson50

https://t.co/ySkyhQcW2m

[Robert Mahar @robertkmahar]

Tragically, kids are often left out of #clinicaltrials.
Not so for the @snap_trial, which brings data from adults and kids together using a sophisticated #Bayesian model.
Our new statistical 'blueprint' details how we make it work (so you can too!).
https://t.co/65ZoYRBeVl

[Robert Mahar @robertkmahar]

If you work on adaptive trials, our recent @BMJMedicine paper on the complexities of concurrent randomisation is a must read!

[Ian Marschner @IanMarschner]

We developed a reporting framework for adaptive clinical trials. It uses the embedded fixed designs within an adaptive trial, which yield unbiased concurrently randomised cohorts. Paper is out in @BMJMedicine

@ascot_trial
@TrialsCentre
@austrim_cre

https://t.co/Zb0i44surT

[Robert Mahar @robertkmahar]

@SarathRanganath Congrats Sarath!

[Robert Mahar @robertkmahar]

Such a great lineup of invited speakers for our second conference! If you are interested in innovative trial methodology make sure to register! In person or online.

[AusTriM @austrim_cre]

We're getting pretty excited to see all our invited speakers - just over a month to go!

Contributed sessions will be announced shortly.

Have you got your tickets yet? 🎫 Join us in Melbourne or online!

https://t.co/LLPaduNkhd

[Robert Mahar @robertkmahar]

@arthur_alb1 @f2harrell Relevant review of ordinal analyses in the 'big 4', led by @_chrisselman, should be published very soon! https://t.co/fi06v92udY

[Melbourne Academic Centre for Health @MACHAustralia]

Miss out on last week’s #EMCR Research Design Webinar? We got you covered!

Catch up on an engaging presentation by Dr @robertkmahar from @MischHub & @MCRI_for_kids on simulation for adaptive trial designs: https://t.co/Ac5WpOAPFg

[Robert Mahar @robertkmahar]

@statsepi Sequential multiple assignment randomised trials (SMART) to the rescue! Chronically underused study design.

[Robert Mahar @robertkmahar]

Pre-print alert!

For when you design #Bayesian adaptive #clinicaltrials with survival endpoints, but don't want to define a hazard functions 🤔 Try a general Bayesian approach!

[Robert Mahar @robertkmahar]

@drbretty @PerinatalAPT Substudies to be referred to as puggles from here on in?

[Robert Mahar @robertkmahar]

@stephenjwild Prior probability of efficacy

[Robert Mahar @robertkmahar]

Love me a decent stats meme.

[Peter Tennant has moved to Bluesky @PWGTennant]

#StatsTwitter #EpiTwitter

[Robert Mahar @robertkmahar]

@Trangucc @jazzystats We have a position open University of Melbourne/Murdoch Children's Research Institute. Lead your own methodological research, and design and analyse a Bayesian platform trial. Heaps of support from strong networks. Get in touch if you would like to chat! https://t.co/9t7e5ejkPm

[Robert Mahar @robertkmahar]

@drbretty The punctuation on that plaque makes my brain hurt.

[Robert Mahar @robertkmahar]

Improve the health of preterm kids as a #clinicaltrials manager for an innovative adaptive platform trial @MCRI_for_kids

[Brett J. Manley 🤷🏼‍♂️ @drbretty]

We are seeking a Project Officer for the implementation of the PLATIPUS @PerinatalAPT to improve outcomes for preterm infants

An exciting opportunity to be part of this new Adaptive Platform Trial @MCRI_for_kids based in Melbourne🇦🇺

https://t.co/AbgLqhAYXw

#neoTwitter #neoEBM

[Robert Mahar @robertkmahar]

We are looking for a new postdoc biostatistician at @MCRI_for_kids in @Melbourne. Help design and analyse an innovative neonatal #Bayesian platform trial and develop new methods as part of @vicbiostat and @austrim_cre
https://t.co/9t7e5eAnRm

[Robert Mahar @robertkmahar]

What an epic thread. Owned a few of these 😎

[Gerry McBride @GerryMcBride]

After the early bricks but before smartphones, there was a stretch where phone design went absolutely catshit bananas (1/?)

[Robert Mahar @robertkmahar]

New bling 👑 50 whole blood donations (in Australia at least). One of the few positives about having haemochromatosis (#ironoverload) is that I need to regularly donate @lifebloodau. Think about doing the same, it’s easy, you get free snacks, and it save lives!

[Robert Mahar @robertkmahar]

@MikeKSmith @werrafoxma #synthwave has entered the chat

[Robert Mahar @robertkmahar]

A great line “randomised care is better than random care”!

[ANZPID @anzpid]

"Randomised care is better than random care". A/Prof @AshaBowen giving us a SNAP-PY @snap_trial summary including current SAB evidence at @ASIDANZ #ANZPID22. https://t.co/td2hN7oY7b #IDTwitter #MedTwitter #infectiousdiseases @syctong @Josh_S_Davis

[Robert Mahar @robertkmahar]

@omaclaren @statsepi …domestic product? That’s more of a macroeconomic concept, I don’t know about them 🤷‍♂️