Rogier J. Nell

MD/PhD student @LUMC_Leiden. Focussing on genetic and epigenetic heterogeneity of uveal melanoma.

[Rogier J. Nell @rogierjnell]

Very happy and proud to share our latest publication: A novel digital PCR-based method to quantify (switched) B cells reveals the extent of allelic involvement in different recombination processes in the IGH locus. https://t.co/cAADrGClHt #bcells #digitalpcr

[rheinbay_lab @rheinbay_lab]

So excited to share our work with @lane_andy on Y chromosome loss in cancer! https://t.co/6iG8xRfav8

[Rogier J. Nell @rogierjnell]

@IreneChristodou @Nature_NPJ @ChildrensLA Congratulations Eirini!

[Hartcentrum Leiden @Hartcentrum]

Onderzoeker @harlaarniels is genomineerd voor de Hugo van Poelgeestprijs. Hij werkt aan de ontwikkeling van nieuwe menselijke hartmodellen ter vervanging van proefdieren bij onderzoek naar hartaandoeningen. Bekijk zijn video https://t.co/VSv06k5Pza & stem op Niels! @Proefdiervrij

[Carel Stolker @CarelStolker]

Oogspecialist prof Martine Jager ⁦@LUMC_Leiden⁩ koninklijk onderscheiden!

Als iemand dat verdient, dan is zij het wel.

Echt indrukwekkend wat zij allemaal heeft gedaan. Zie ⁦@Sleutelstad⁩ 👇🏼👇🏼 https://t.co/u0btXDay9p

[Leidsch Dagblad @leidschdagblad]

Lex van der Eb geëerd in Leiden: Emeritus hoogleraar is uitvinder belangrijke vaccinatietechnologie https://t.co/9zO5YMAiSp

[Rogier J. Nell @rogierjnell]

Thrilled to present our latest research 'Vitreous fluid as a new liquid biopsy for primary uveal melanoma' during the ISOO congress in hometown Leiden!

[CURE Ocular Melanoma @MRFCureOM]

Exciting news for the European OM community! In addition to @US_FDA approval in January for ocular melanoma patients in the US, Kimmtrak has now been approved by the European Commission to treat patients with unresectable or metastatic uveal melanoma. https://t.co/6cgqMP29r8

[LUMC Leiden @LUMC_Leiden]

LUMC-artsen hebben een bloedtest gemaakt die aantoont of iemand huidlymfomen, een vorm van #huidkanker, heeft. Dit is belangrijk omdat de symptomen vaak worden gemist. Hun volgende doel is om de test in heel Europa beschikbaar te maken ➡️https://t.co/sw46DmRwtH #wereldkankerdag

[Nature Biomedical Engineering @natBME]

Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics

https://t.co/OofbRIKCfs

[Rogier J. Nell @rogierjnell]

Congratulations @harlaarniels on this amazing work: "Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation", just published in Nature Biomedical Engineering. https://t.co/ltNzj9CzVG

[Kane Foster @KaneFos]

Why would αβ T cell clones selectively express a γδTCR chain? #scRNAseq #TCR #singlecell

[Rogier J. Nell @rogierjnell]

Very proud to share our latest work: Accurate quantification of T cells in copy number stable and unstable DNA samples using multiplex digital PCR https://t.co/cz6U6bmz3T

[Rogier J. Nell @rogierjnell]

Amazing application of our DNA-based methodology to quantify T cells using #digitalPCR (see https://t.co/JSnLYCJo3f) #HIV

[Cell Reports Medicine @CellRepMed]

Researchers describe a highly multiplexed droplet digital PCR assay that simultaneously quantifies likely intact HIV-1 proviruses and T lymphocytes. They validate the assay in cell and tissue specimens from several patient cohorts. @UWashOBGYN @fredhutch @UWMedicine

[Stichting Melanoom @StMelanoom]

Nieuwe Melanoom Info Webinars op zaterdag 26 juni open voor inschrijving!
Zie voor programma en aanmelding:
14.00-15.30 huidmelanoom ->https://t.co/8aqjMEBRTs
16.00-17.30 oogmelanoom -> https://t.co/oNU9v4v4tC
#stichtingmelanoom #melanoominfowebinar #melanoom #oogmelanoom

[Alexander Roesch @RoeschAlexander]

B cells in melanoma might not always be a positive predictive biomarker, we actually found the opposite in D/T-treated pts

Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib https://t.co/6pZP3snsg3

[National Cancer Institute @theNCI]

The Cancer Genome Atlas is pushing the boundaries of #CancerResearch. Visit our website to discover how the Atlas has made an impact through researchers who have used the data to make a difference in the lives of people with cancer. https://t.co/wG0LrFfdkp #NothingWillStopUs

[LUMC Leiden @LUMC_Leiden]

Onze oogartsen dr. Irene Notting en dr. Yanny Cheng slaagden erin beide lenzen in de ogen van chimpansee Fiffy te vervangen. Lees meer over deze bijzondere ingreep ➡ https://t.co/vVKC79E2aA Foto: Marina Marinkovic

[Rogier J. Nell @rogierjnell]

More applications of our method and some exciting results coming soon! Thanks to Wim Zoutman and Pieter van der Velden @LUMC_Leiden for this wonderful collaboration! (5/5) #digitalPCR

[Rogier J. Nell @rogierjnell]

I am thrilled to share our recent work, now published as a patent application https://t.co/ELiJI4BVNs. We developed a digital PCR-based approach to quantify T cells, B cells and class-switched B cells in benign and malignant DNA samples. (1/5)

[Rogier J. Nell @rogierjnell]

By measuring the total amount of DNA and its origin (T cells or B cells), our approach is capable of differentiating between a benign uveitis and malignant lymphoma (see image). I will virtually present this work at @ARVOinfo's Bench to Bedside Meeting (May 20-21). (4/5)