@ChemEpi@KRHornberger@HartungIngo Have you tried adding albumin or FCS? If that is not sufficient then small amounts (below CMC) of non-ionic detergent, like Tween or Triton could be beneficial as well. Avoid the use of organic cosolvents. What was the reason for the problem with Cremophor?
Our first preprint is online now:) Biotinylated and fluorescent derivatives of acetonyl CoA as probes for Histone acetyltransferases. Thanks @RomanSimon14 for great work. Nice collaboration with A. Akhtar from @mpi_ie Paper submitted to Journal as well.
https://t.co/uXaS6k235U