Check out our latest paper on efficacy photoswitches that can locally light up opioid receptors, thus avoiding unwanted central and peripheral side effects (respiratory depression, constipation). Great collaboration with Levitz (Weill Cornell), @CorneliusGati (UCX) and @sevakat1 (USC)
https://t.co/VQWqvCEfAm
@mfgrp@rdavbritt How sad to hear about Jon’s passing. He was a giant in the fields of natural product chemistry and chemical biology. He will be greatly missed.
Our AM-3 paper is out in Cell. Opioids are critical drugs, but have severe side effects. Because they are administered systemically, it is hard to dissect how they work, and to separate side effects. So we built one you can switch on and off with light. https://t.co/9sb9TRvA2Q
I am thrilled about the Nobel Prize for Optogenetics. Congrats to Peter, Georg, and Karl! And I’m happy that the Nobel committee correctly portrayed the role Chemistry played in the development of this field: https://t.co/BxywPiMtEy
Looking for somewhere nice and cool to attend conferences/symposiums and hear inspiring and cutting-edge developments of organic chemistry? Come to join us at Minneapolis next July for the 2027 National Organic Chemistry Symposium! #NOS2027
Nuclear Receptors and Photopharmacology are a great match. Check out our latest work on glucocorticoid receptors, in a wonderful collaboration with the De Bosscher lab: https://t.co/x16dg8mWA6
The Department of Chemistry at the University of Pennsylvania invites applications for a tenure-track position at the rank of Assistant Professor in the broadly defined area of organic chemistry. I have the honor of chairing the search committee.
https://t.co/3WDXOp4ure
Feeling down? Reviewer 3 was nasty? 13C-NMR doesn’t match? TLC shows an Autobahn? Tomorrow is another day. And our “Need Motivation” button is back! https://t.co/sasFhXxbIY
I've been dabbling a lot with @Claude coding and wanted to modernize the POCC website (again). In doing so we've added a ton of new features to the site and were able resurrect a lot of lost records. We've also added modern tools like calendar integration etc, go check it out!
I've been dabbling a lot with @Claude coding and wanted to modernize the POCC website (again). In doing so we've added a ton of new features to the site and were able resurrect a lot of lost records. We've also added modern tools like calendar integration etc, go check it out!