Rodney Samaan

#preventive #cardiologist. #author #medical advisor @cardaxpharma

[🏠 BOXABL 🏭 Galiano Tiramani @GalianoTiramani]

Love this place! @boxabl https://t.co/nPQm9db2hu

[Camus @newstart_2024]

Jamie Dimon nearly died on March 5, 2020.

He suffered an aortic dissection and needed emergency open-heart surgery. He knew a lot of people never even make it to the hospital, and many who do never leave the ER. In that moment he called his wife, told her company what was happening, and realized he had no major regrets.

Great kids. Great wife. Great company. He had done the best he could. Mistakes happened, but nothing that haunted him as life potentially ended.

He later said the prolonged pain of throat cancer and chemo years earlier was actually harder than the sudden heart event.

A clear-eyed look at what mattered when the clock almost stopped.

[Ilyas @Milyas_K]

@Mimiiben1

[Mimi😽 @Mimiiben1]

Kalem kullanmadan çözebilirsen sen bir sayısal dehasın..

Yapabilir misin?

[Paul Minot, MD @PaulMinotMD]

@Mimiiben1 The square root of 49 is 7. The square root of 81 is 9, and the square root of 9 is 3. 7 plus 3 is 10. The square root of 4 is 2. 10 divided by 2 is 5.

[The Biohacking Immortal @1Immortals1]

broccoli sprouts sound like something a wellness influencer invented to sell mason jars until you read the NRF2 research coming out of johns hopkins.

sulforaphane is the most potent natural activator of the body's master detoxification pathway ever discovered. then it stops sounding like vegetables and starts sounding like pharmacology

NRF2 is the master switch that controls over 200 protective genes simultaneously. when activated it turns on your body's entire antioxidant defense network at once. not one gene. two hundred. sulforaphane activates NRF2 more powerfully than any other natural compound ever tested. that's it. one molecule. two hundred genes. the most efficient input-to-output ratio in nutritional science

- induces phase 2 detoxification enzymes that neutralize carcinogens before they damage DNA. studied extensively at johns hopkins for over 25 years
- reduces tumor size and number in animal cancer models. human clinical trials actively running
- crosses the blood-brain barrier. neuroprotective against parkinson's markers in preliminary research
- improves markers of autism spectrum disorder in a randomized controlled trial. one of the only compounds shown to do this
- reduces inflammatory markers across every tissue tested including gut, liver, and brain
- enhances your body's ability to process and eliminate environmental toxins, heavy metals, and air pollution particulates

the catch that the supplement industry exploits: you need broccoli SPROUTS not mature broccoli. sprouts contain 10-100x more sulforaphane precursor than the broccoli at the grocery store. and most sulforaphane supplements are missing myrosinase, the enzyme needed to convert the precursor into active compound. without myrosinase the capsule is biologically inert

grow your own. mason jar. sprouting seeds. water. 3-5 days from seed to edible sprout. costs literally pennies. eat 30-60g daily. or buy a supplement that explicitly contains myrosinase (check the label, most don't)

the most powerful chemoprotective compound in nature grows in a mason jar on your kitchen counter in 3 days for less than the cost of a coffee. the supplement industry would rather sell you 47 antioxidant pills than tell you about a seed that costs nothing

[Mary B Schanck @MaryBschanck]

$CAPR This mysterious slide appeared during the discussion and, to me, captured the core issue. The Advisory Committee debate didn’t seem to center on whether deramiocel demonstrated biological activity or potential clinical benefit. Instead, much of the discussion focused on how the data should be interpreted, the statistical analyses, and whether the evidence met the FDA’s regulatory standard for approval.

That’s an important distinction. The conversation appeared to be as much about regulatory evidence and methodology as it was about the therapy itself.

Just my interpretation. Curious how others viewed it.

[Jesse Brock @JesseBrockVan]

This is the face of DMD. @US_FDA @Capricor @SenRonJohnson @RobertKennedyJr Approve Deramiocel!

[Lorwen Harris Nagle, PhD @LORWEN108]

8. Sunlight does far more than produce vitamin D.

Different wavelengths of natural light reach the body throughout the day.

Kruse argues that these changing frequencies help coordinate hormones, circulation, cellular energy and sleep.

A vitamin D capsule cannot reproduce the entire solar signal.

[Lorwen Harris Nagle, PhD @LORWEN108]

7. The time you eat matters as much as what you eat.

Your body is generally better prepared to process food during its active daylight period.

Eating heavily late at night sends energy into a system preparing for repair and sleep.

Kruse’s point:

Your biology reads the clock before it reads the menu.

[Jake Gilman @jakeglmn]

A University of Birmingham study of 200 adults found:

3,000 steps/day → high inflammation
5,000-7,000 steps/day → 50% less inflammation
10,000 steps/day → zero inflammation

[Jake Gilman @jakeglmn]

If your inflammation is out of control, you'll feel exhausted no matter what you try.

Most people don't realize it's the silent cause behind almost every chronic disease.

Here are 8 ways to kill inflammation naturally (& get your energy back):

1) Walk 10,000 steps

[Historic Vids @historyinmemes]

“Above all, do not lose your desire to walk.”

- Søren Kierkegaard

Søren Kierkegaard wrote these words in an 1847 letter to his ailing sister-in-law, emphasizing that walking was essential not only for physical health but also for mental clarity. The Danish philosopher, who was known for his daily walks through the streets of Copenhagen, believed that constant movement was one of the best remedies for existential anxiety and mental stagnation.

By saying he could walk away from even his heaviest thoughts, Kierkegaard portrayed walking as more than a simple distraction. He saw it as a powerful way to work through grief, anxiety, and life’s most difficult questions. His words remain a timeless reminder that physical movement can inspire emotional and intellectual progress, while remaining still can leave us feeling trapped.

[Call a friend Grok @runlolarn]

The ⁠FDA relied on an outdated, unsigned analysis plan, Capricor CEO Linda Marbán said, arguing that it "pigeonholed the whole meeting into a discussion of which stat plan was right, which imputation model was right and how the data should be looked at for one or ​two patients."
Marbán said that ​focus ignored the ⁠totality of the evidence and the impact on people with DMD and their families.
Cantor Fitzgerald analyst Kristen Kluska said the FDA staff ​hosting the meeting seemed "extremely negative during the entire conversation and ​were going ⁠into this meeting with the mindset to reject the application".
https://t.co/34JpmuUd7H
Having shared that:
Strong pushback from $CAPR CEO Linda Marbán and Cantor Fitzgerald’s Kristen Kluska on the FDA’s AdCom stance. Hard to ignore how adversarial the briefing docs were, focusing on an outdated SAP draft rather than the final dataset.
Technical biostatistics shouldn't obscure real patient benefit.

[🏠 BOXABL 🏭 Galiano Tiramani @GalianoTiramani]

These vacation @boxabl hooked up to @starlink 😍

[Jesse Brock @JesseBrockVan]

Brilliant post Adcom Analysis! Deramiocel must be approved!@Capricor $CAPR @ParentProjectMD @SenRonJohnson @RobertKennedyJr @realDonaldTrump @houmanhemmati
@Elijahjstacy

[Elon Musk @elonmusk]

That’s my actual car that I drove for 3 years that is currently orbiting the Sun between the Earth and the edge of the asteroid belt

[FlyingEagle @FlyingEagle86]

Narrower, function‑focused approval + strict phase 4. Approve on the cleanest, most convincing piece (PUL/upper‑limb), require real, enforceable post‑marketing work on cardiomyopathy and long‑term outcomes. $CAPR

[CapitalHuntersClub @CapitalHuntersC]

Look at the raw numbers in The Lancet publication: Deramiocel showed a 54% slowing of upper-limb decline versus placebo in HOPE-3. For DMD patients losing independence, that is a life-changing clinical benefit. The market is trading the bureaucracy, not the biology. $CAPR