Exploring virulence in Mycobacterium bovis: clues from comparative genomics and perspectives for the future.
Mitermite et al (2023). Irish Veterinary Journal 76 (Suppl 1), 26. @mbovis2022#openaccess#Mycobacteriumbovis#OneHealth https://t.co/XKySoQONjG
Pioneer studying Mycobacterium #tuberculosis, Sabine Ehrt has lead substantial discoveries on this death-causing pathogen – she shared her experience in this spotlight by @DrBommel 👇
https://t.co/BTE5NNvuiA
I'm really happy to share this preprint fully @EhrtSchnapLab made. In a partnership with @wintersunyuan, we propose that M. tuberculosis NADH dehydrogenases (Ndh-1 and Ndh-2) are essential for NADH oxidation but dispensable for oxygen respiration. https://t.co/tWWhjzofvf
Our ambitious study defining the genes required for the survival of M. bovis in cattle is finally out in MBio! We used Tnseq to identify 300 genes required for survival and show commonalities with mouse models. We identify some novel virulence factors and
A historic moment in the world of molecular structural research. #AlphaFold structure predictions for 22 species made freely available by @deepmind, access through @uniprot and @PDBeurope. Learn more at https://t.co/CFOFytruww
Ruoyao Ma is a fourth year PhD student at the Vet School researching the pathogens that cause tuberculosis (TB) in humans and animals using a One Health approach🦠https://t.co/VwUsXVx1Nf #WomenInScience@WomenScienceDay @ucdvetmed @DohertyVetDean @UCD_EDI@WomenInSTEM_UCD
"Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference"
New research by @steve_myco, Nacho Aguiló and colleagues @ucddublin@unizar
https://t.co/uZkiCIKt3p
A postscript to our @PLOSPathogens paper:
Bioinformatics and other bits - Detecting polymorphisms in the RD900 region of MTBC species https://t.co/nwbzOqQK3D
@ucddublin@UCD_OneHealth @steve_myco
@UCDInfectionBio The author concluded that et immunization induced a mix Th1/Th2 response by detecting the related cytokines. Do you think would it be better if they could also conduct IgG subtyping to confirm the conclusion? #ccib2019week18
@UCDInfectionBio Fig1B. The Malt1 is highly expressed in CX3CR1+MNPs compared to DCs , but no information about Malt1, what’s the specific function of it? Would it be better if they could discuss more details and links among the genes on the heatmap #ccib2019week17
@UCDInfectionBio Why they used the old cow urine as odour bait to capture tsetse? Do different baits attract different species of tsetse and effect the statistical result? #ccib2019week11
@UCDInfectionBio The faecal samples were stored at -20℃ before DNA extraction. Can freezing decrease the relatively abundance ratio of some phyla? Would it be better if they used fresh faecal samples or used methods like OMNIgene.GUT to collect and stabilize DNA? #ccib2019week10