Ryan Moon

Cardiovascular Researcher

[Kurt Prins @kurt_prins]

Excited to see this one out. https://t.co/6DQpx1KIFt. Estrogen muzzles microtubules to protect the RV! Huge thanks to @TimLahm for helping use get this one across the line! @jclinicalinvest made this a wonderful experience! @ResearchMUSC @MUSC_Cardiology

[MUSC Department of Medicine @MUSC_IM]

Congratulations to @MUSChealth cardiologist & physician-scientist @kurt_prins on his election to the prestigious American Society for Clinical Investigation. He is the 1st MUSC physician-scientist elected since 2014. Learn more: https://t.co/E3YSEhW86H

[Kurt Prins @kurt_prins]

Do you want to know the cellular and molecular determinant of progressive RV dysfunction? @Jenna_Mendelson caps off her PhD thesis to define them in a porcine model: https://t.co/yeE9dJfKJv

[Circulation Research @CircRes]

@jenna_mendelson et al found #GP130 inhibition enhances #RV function in a model of RV dysfunction. Learn how multi-omics analyses highlight the #inflammatory, #vascular, & #metabolic mechanisms counteracted by GP130 inhibition at https://t.co/BjzzhtdA2z
@kurt_prins

[Kurt Prins @kurt_prins]

@Jenna_Mendelson masterpiece on the role of GP130 in porcine RV dysfunction. Thanks @CircRes for publishing our work! @PVRI @MUSC_Cardiology @ResearchMUSC @ATS_PC @AHAScience @RyanTedfordMD @mark_toshner https://t.co/haoiEzISko #ChangingWhatsPossible @sbonnet2 @ACCinTouch

[Jenna Mendelson @Jenna_Mendelson]

My thesis paper is out in @CircRes! We did a little bit of everything in this one: single-nucleus RNA seq, electron/confocal microscopy, proteomics, metabolomics, lipidomics - all in large animals to show how GP130 antagonism improves RV function in pigs. https://t.co/HcGLUblGsk

[Kurt Prins @kurt_prins]

Out now in @CircRes, @Jenna_Mendelson, defines the cellular and molecular landscape of the dysfunctional RA! @UMNIBP @ResearchMUSC @MUSC_Cardiology @3CPRCouncil @PVRI @ATS_PC @MUSC_COM @mark_toshner @RyanTedfordMD https://t.co/GSDiKSp326.

[Kurt Prins @kurt_prins]

Led my @MadelynJBlake, our latest pre-print in which we performed a multi-tissue, multi-omic, multi-species, and multi-continent evaluation of BCAA metabolism in PAH and liver dysfunction. @ResearchMUSC @MUSC_Cardiology @MUSC_COM https://t.co/VOx0yyrmSu.

[MUSC Research @ResearchMUSC]

New work from MUSC Gazes Cardiac Research Institute Director @kurt_prins defines a multi-omic signature of skeletal muscle dysfunction in PAH. https://t.co/gyI4EeXWCo

[Sasha Prisco, MD, PhD @SashaPrisco]

It's the end of an era! I'm going to miss being able to see you almost every day. I am excited to see all of the amazing things that you will do at @MUSC_Cardiology! It's not goodbye, it's see you later. @kurt_prins @RyanTedfordMD @thenappanMD @UMNPHProgram @UMN_DCVM @LilleheiHrt

[Sasha Prisco, MD, PhD @SashaPrisco]

Prisco Lab this summer! So thankful to work with all these talented and enthusiastic people! Looking forward to a fun summer! @BenjaminPKremer @ryan_moon3 @rashmimr02 @LilleheiHrt @UMN_DCVM

[Sasha Prisco, MD, PhD @SashaPrisco]

Thank you @CircHF for the opportunity to share our work on how modulating the gut microbiome may be an approach to enhance RV function in PAH. Grateful to the entire research team for their help on this project. @ATS_PC @3CPRCouncil @PVRI @GiessenPh @RyanTedfordMD @GMFHx

[Kurt Prins @kurt_prins]

https://t.co/RhQa51e5Vl. @SashaPrisco shows Lactobacillus treatment alters the micro/mycobiome improves RV function via an inflammatory-microtubule axis in @CircHF! @3CPRCouncil @PVRI @ATS_PC @metagenomics @RyanTedfordMD #microtubules

[Kurt Prins @kurt_prins]

Finally across the finish line! Excited to share with the community very soon @SashaPrisco's work showing modulating the micro/mycobiome with Lactobacillus has anti-inflammatory effects and combats rodent RV failure. @3CPRCouncil

[Kurt Prins @kurt_prins]

Sex, drugs, and microtubules? Excited to share our latest preprint showing estrogen can exert cardioprotective effects by combatting microtubule densification in the failing RV. https://t.co/4o3kNB4IU9. @3CPRCouncil @UMN_IBP @LilleheiHrt #microtubules.

[Kurt Prins @kurt_prins]

Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs. https://t.co/9UIjHo8RtS. Proud to get this one out and close off 2024! @RyanTedfordMD @PVRI @ATSBlueEditor @umnmedschool @LilleheiHrt @UMN_DOMResearch @ATS_PC

[Kurt Prins @kurt_prins]

https://t.co/hncshJtfHP. Excited to share our journey of ferroptosis in PAH. Thanks to generous collaborators @Lab__Williams @VUMC_heart (Evan Brittain), @therealtyrone50 and Christopher Rhodes! @CircRes @LilleheiHrt @UMN_DOMResearch @PVRI @ATS_PC @PHAssociation @SashaPrisco

[Lillehei Heart Institute @LilleheiHrt]

New article in Circulation by Drs. Kurt Prins and Sasha Prisco highlights a previously unknown function for protein junctophilin-2. (https://t.co/UoIU2ShJdB) #UMNresearch #UMNheart #UMNproud #Cardionerds

[Kurt Prins @kurt_prins]

From the microbiome to the microtubules: Latest preprint led by @SashaPrisco showing the anti-inflammatory bacteria Lactobacillus can counteract systemic inflammation-associated microtubule remodeling in RV failure. https://t.co/TgknZp2Z5B @3CPRCouncil @PVRI @UMNresearch

[Sasha Prisco, MD, PhD @SashaPrisco]

At our semiannual MN PH Consortium co-hosted with @MayoClinic. We have a wonderful clinical and research @UMNPHProgram program & it's a pleasure to work with this team! @thenappanMD @kurt_prins @wigzhez1 @BryanThieryRNCC @Jenna_Mendelson @BenjaminPKremer @UMN_DCVM