Friedberg: New study shows enzyme reverses skin age from 70+ years to 31
Chamath: That’s a $2T market.
Did Scientists Just Discover How to Reverse Skin Aging!?
“CML is kind of the predominant molecule that gets formed in this extracellular matrix that's driving aging, and nothing breaks it down.
So these scientists set out to try and create an enzyme, an enzyme is a protein that breaks something down, that can break down CML.
And so these guys kind of went out and they took the target, which is CML, and tried to figure out, ‘Okay, how do we actually degrade CML, clear that extracellular matrix, and reverse aging?’
They started to test it on the proteins that we would find in our body, casein, collagen, retinal proteins, which are in your eye, hemoglobin, and they were able to get rid of 52 to 97% of the CML, just degrade it away.
And then they found several sites where they were able to degrade over 90%.
And then they took actual human skin from elderly patients that had donated their skin, and they put this enzyme onto that skin, and they were able to eliminate 55% of the CML on the skin, basically reverse the skin's age down to the age of a 31-year-old, this is from greater than 70-year-old patients, just by putting this enzyme on the skin.
And so it's kind of a groundbreaking demonstration of combination of AlphaFold, what's called directed evolution, where you change the order of the DNA that changes the structure of the protein to test different proteins, do high throughput screening, and ultimately make a novel protein that doesn't exist in nature today that can do something pretty profound for human health.”
Chamath:
“It will be a trillion-dollar market. If you can create a cream…”
Friedberg:
“I mean, dude, if you could put this enzyme literally on your skin and have it absorb in…”
Chamath:
“Game over. That alone is $2 trillion.”
@grablekelly05@CAgovernor@JenSiebelNewsom And the reality is go look at the trash cans at the lunch tables. They're filled with uneaten pieces of fruit and carrot sticks. Ask any lunch lady. She will tell you. It's total waste.
Laotian national Tou Lue Vang was convicted of sexually abusing a 10-year-old girl in Minnesota.
He was set to be deported until @GovTimWalz issued him a pardon.
Then, I revoked his legal status. @ICEgov has removed him from the U.S. and he will never endanger another American.
@blickertyblack@the_jefferymead You're just like the democrat California legislators. Attack the person calling out the bad guys rather than calling out the bad guys.
More than 250 runners are crossing the country as part of Relay for America, carrying the U.S. flag to Washington, D.C., with the goal of arriving by July 4th. Each mile of the journey is dedicated to a veteran who served our nation.
America faces more than a chronic disease epidemic that threatens our physical health. We also face a spiritual malaise that undermines our mental health.
Our children are increasingly isolated, fragmented, and anxious, spending more than 8.5 hours a day on screens.
This summer, put down the phone and reconnect with nature, family, and community. It's time to Take Back Your Health. Eat Real Food. Get Active. Together, we will Make America Healthy Again.
@grok She’s worried about smog like 60s/70s CA. But old car exhaust was far worse than today’s cleaner fleet + EVs. Modern cars are much cleaner thanks to: catalytic converters & strict standards (CARB); better tech like fuel injection & filters; zero tailpipe EVs + fleet turnover. I believe it won't revert to the smog of the 60s/70s/80s. Why won’t it revert?
Today, on my final day as Director of National Intelligence, I’m releasing never-before-seen communications and documents exposing how Dr. Fauci provided millions in US taxpayer dollars to fund dangerous gain-of-function research at the Wuhan lab, worked with politicized elements within the Intelligence Community to suppress the truth about his actions and hide the virus’ lab-leak origins, and lied to Congress while under oath in 2024. It’s time you know the truth.
https://t.co/3YJSstB7d4
History's first trillionaire is a guy who catches rockets out of the sky with chopsticks and beams internet to every dead zone on the planet.
Same guy ships cars that drive themselves, humanoid robots for the factory floor, brain chips that let paralyzed people move a cursor with pure thought, and an AI running on a supercomputer his team stood up in months instead of years.
And the people crashing out about his net worth are doing it on the app he owns. The same app governments spent years trying to censor.
You cannot legislate a rocket into orbit.