Great fun to describe our journey in chemical and systems biology of bacteria for Accounts of Chemical Research. So fitting to co-author this work with my hugely talented Research Associates Maya Farha and Shawn French who have blazed this trail. https://t.co/Vdm9r7XSGV
With growing evidence that carbon utilization is an Achilles heel for many pathogens, @maddytong led a genome-scale look at the growth of E. coli in 30 carbon sources. Shout out to the Karp Lab and the new metabolic modelling capabilities of @BioCyc.
I continue to be amazed by the contribution of physiological bicarbonate to antibiotic action. Very proud of this effort led by Maya Farha. Good fun as always to work with @agmcarthur laboratory. https://t.co/06QMxJv81t
Bacterial responses to stressors offer insight into their complicated biology. A @NatureProtocols paper led by Dr. Shawn French describes a detailed, step-by-step methodology for any lab across the globe to produce & program their own PFIboxes. https://t.co/bQhxlDNh8i
Excited to share our discovery from @eric_brown_bbs lab of a novel antivirulence agent that reverses b-lactam resistance in MRSA. Was fun collaborating with @deheinrichs and @McGavLab @WesternU and Mike Organ @OttawaU and Richard Epand @McMasterU on this! https://t.co/ERCv4SneMk
Happy to see our work published in @NatureComms today! We found a new antibiotic scaffold that kills intracellular #Salmonella Typhimurium and discover OM disruption in macrophages.
Great working with @CaressaTsai on this
@McMasterIIDR@MacHealthSci
https://t.co/Qa3iLHI8Yv
@MacFacilities Hey @MacFacilities the 5201 water fountain's sensor (MDCL, 1st floor) doesn't work most of the time. Could you please have a peek at it? Thanks!