@erastourticketz Well, I'm trying to channel my reputation era but truly more in my folklore/evermore era... I just moved to the Bay Area from Philadelphia and I haven't found any friends yet who would go to the show with me.
I still can't believe it, but thanks everyone for the congratulations 😊 It's been the best ride with such incredible mentors and friends @GardiniLab@marcotrizzino@ElisaBarbieri17 Now, to get that paper published...
Stoked to share this preprint of our awesome collaboration with @JohnstoneLab, a culmination of my PhD research with the awesome folks in the @GardiniLab! We found a new role for the Integrator complex in recruiting the phosphatase PP2A to sites of active transcription (1/n)
aberrant transcription of genes that are normally tightly controlled. Using a combination of CDK9 inhibition and PP2A activation forces the red light from both sides of this opposition, leading to successful treatment and increased survival in a mouse model of AML! (6/n)