Schubes

Microbiologist and Scientist exploring climate-tech. Cat dude, mediocre drummer. Formerly Berkeley/Amyris/Harvard/Wyss Inst.

[Schubes @Schubes0]

New preprint: Cyanobacteria isolated from marine volcanic seeps display rapid sinking and robust, high density growth. Thanks to U Palermo and Two Frontiers Project, we got unique samples from Vulcano, Italy, where CO2 bubbles into the shallow ocean, 24-7! https://t.co/bYlrM2gukS

[Michael 英泉 Eisen @mbeisen]

How do you publish this tree and claim it's a success???!!!

[PioneerLabs @Pioneer__Labs]

This tube is a library of bacteria with every single-base-pair genome mutation, all DNA-barcoded.🧪Growth + barcode sequencing = data on millions of mutations.

📄 Report: https://t.co/llvs1wUbVk

Retweet if you want more data, and read on if you want to use the library! 🧵

[Schubes @Schubes0]

@ProfTomEllis Updates to this work: revised manuscript, blog post, addgene libraries available:
https://t.co/cu5zhvrINs

[PioneerLabs @Pioneer__Labs]

This tube is a library of bacteria with every single-base-pair genome mutation, all DNA-barcoded.🧪Growth + barcode sequencing = data on millions of mutations.

📄 Report: https://t.co/llvs1wUbVk

Retweet if you want more data, and read on if you want to use the library! 🧵

[Wyss Institute @wyssinstitute]

An international coalition of scientists discovered a novel cyanobacteria strain adept at “eating” CO2 and sinking in water. It is a prime candidate for biologically-based carbon sequestration projects & bioproduction of valuable commodities.
https://t.co/MRf3xu5V6e

[Schubes @Schubes0]

@LindzBro @wyssinstitute It's been awesome to hear from researchers that are getting ahold of "Chonkus" and trying it out in their lab. Wishing you all the best, and don't hesitate to reach out. https://t.co/JLaco81mj8

[Schubes @Schubes0]

New preprint: Cyanobacteria isolated from marine volcanic seeps display rapid sinking and robust, high density growth. Thanks to U Palermo and Two Frontiers Project, we got unique samples from Vulcano, Italy, where CO2 bubbles into the shallow ocean, 24-7! https://t.co/bYlrM2gukS

[Schubes @Schubes0]

Published version live today in AEM: https://t.co/ReaXtOS0Yi alongside some commentary from @LindzBro @wyssinstitute https://t.co/i3VjPHeyGJ

[Schubes @Schubes0]

@ATinyGreenCell for commercial efforts that is an absolute steal compared to negotiating a license, i suppose. If you are using it for research/education i would get it from NCYC and only cross the licensing bridge if you ever need to?

[Schubes @Schubes0]

Once again seems to have aged poorly, this time recent Nobel News.

[Michael 英泉 Eisen @mbeisen]

C. elegans. They wiggle forward. They wiggle backwards. And occasionally they fuck themselves. That’s it.

[Schubes @Schubes0]

@ATinyGreenCell I have used these https://t.co/v9UoLZp82S and like the way they measured their activity. Many different sequences.

[Schubes @Schubes0]

Can we settle once and for all how to pronounce "-mycin" antibiotics?

[Schubes @Schubes0]

@ATinyGreenCell https://t.co/bP82qQiuF6 predicts pKanR at ~5k units, pAmpR at ~2k units, and the strongest promoters i've seen are maybe ~12k units. not perfect prediction, but generally a good vibe check

[Schubes @Schubes0]

@ATinyGreenCell Same vibes: https://t.co/hOfMQ7y9YJ

[Schubes @Schubes0]

@ATinyGreenCell Truly amazing and I agree. At the same time, I think future biologists will find PCR barbaric “you would fully DENATURE the DNA and then SMASH it back together? Like 30 times?” Potentially isothermal or synthesis will overtake it?

[Schubes @Schubes0]

@TLowePower Not always the most possible/practical, but have DIY on your list of possibilities. Outfitting a fridge with a pet store heating pad with heat/cool on a hardware store controller will run you less than $500 and fridges are available in countless sizes.

[Schubes @Schubes0]

@kaia_mattioli Incredible news! hope to celebrate with y’all soon.

[Schubes @Schubes0]

Lol also if you are interested in hearing me blubber about this on local radio have a listen (segment starting about 37:00) https://t.co/1v0jl1LaNl

[Schubes @Schubes0]

Tagging @izzymgm @ZijayTang @bradentierney @geochurch @mason_lab @MeclabU
@twofrontiers @krista_ryon @seedhealth @wyssinstitute @jkowitz and more- ongoing updates to the story forthcoming.