Sean Shirvani MD MPH

Chief Medical Officer @reflexionmed. Feel pretty good about some of my dad jokes. Tweets mine.

[Heath Skinner, MD PhD @HSkinnerMDPhD]

Our amazing #physicist Dr. Shada Wadi-Ramahi speaking to our experience optimizing work flow @UPMCHillmanCC #radonc on our @reflexionmed X1. Looking forward to our first SCINTIX treatment in the near future!

[Sean Shirvani MD MPH @SeanShirvaniMD]

@TeWilliamsMD @reflexionmed @cityofhope @COH_RadOnc Thanks so much for the kind words - we are very lucky indeed to collaborate on these exciting developments with partners like City of Hope

[Sean Shirvani MD MPH @SeanShirvaniMD]

An incredible journey with an outstanding group of individuals - congratulations to everyone involved in bringing this new radiotherapy technology to the world, from conception to first patient treated! 🎉

[RefleXion Medical @reflexionmed]

"This first SCINTIX treatment is a watershed moment for physicians and patients alike because finally, we have a technology with the potential to meet the challenges of treating metastatic disease head on. Clinical literature and emerging practice guidelines are beginning to incorporate the importance of treating all visible disease in certain cancers. SCINTIX was conceived with that end in mind, and to work in combination with drug therapies to improve outcomes, especially for patients with advanced-stage cancers." – Todd Powell, President and CEO of RefleXion. https://t.co/z31JpggmPv

[Murat Surucu @Mur_Sur]

✅ Today marks the successful delivery of the final BgRT treatment fraction for the first patient👏 @StanfordRadOnc 👏@SUMedPhysics 👏@reflexionmed

[Sean Shirvani MD MPH @SeanShirvaniMD]

CONGRATULATIONS!

[Murat Surucu @Mur_Sur]

A milestone today: Patient treated with biology-guided radiotherapy via SCINTIX technology. Kudos to @StanfordRadOnc & @reflexionmed teams for their collaborative dedication and pioneering approach in integrating new technology for #cancer care!

[Sean Shirvani MD MPH @SeanShirvaniMD]

Stoked that @lukevitzthum gave the very first conference presentation of the clinical trial data that supported the approval of SCINTIX in the US. Congratulations to Lucas and all his co-investigators on completing this critical study! #ESTRO23

[RefleXion Medical @reflexionmed]

Great presentation at #ESTRO23 today by @lukevitzthum from @StanfordRadOnc! This was the first presentation of BIOGUIDE-X: A First-in-Human Study of the Performance and Safety of Biology-Guided Radiotherapy.

[Sean Shirvani MD MPH @SeanShirvaniMD]

Thanks for your enthusiasm @jamesbyu about SCINTIX. Buy in from med onc and nuc med is key to this technology that crosses disciplines. Look forward to working with you in the future.

[James Yu @jamesbyu]

@YaleRadOnc @cd_fuller @reflexionmed Wish I was there to see it. When I first started the conversation and effort to bring @reflexionmed to Yale, I was gratified by the buy in from Med onc and nuc med and pet center colleagues, from melanoma to gi to lung to Gu. Can’t wait to hear about scintix and read the papers!

[Sean Shirvani MD MPH @SeanShirvaniMD]

It’s been quite the journey! -l am so proud to announce that BgRT is officially FDA cleared. Bringing to market a novel hybrid of a medical device and an injectable wouldn’t have occurred without a very special, pioneering and capable team - thanks and congrats to all involved!

[RefleXion Medical @reflexionmed]

"SCINTIX ushers in a new era of external-beam radiotherapy by harnessing data produced from the biologic process of cancer cells, which until now has been untapped,” said @TeWilliamsMD, chair of City of Hope’s Department of Radiation Oncology. https://t.co/Dnb0Gj8l52

[Sean Shirvani MD MPH @SeanShirvaniMD]

Super proud!!

[California Life Sciences (CLS) @CALifeSciences]

The winner of the #Pantheon2022 Convergent Technologies Award is… @reflexionmed! 🎉

[RefleXion Medical @reflexionmed]

We are thrilled to announce SCINTIX as our new brand name for our breakthrough biology-guided radiotherapy technology! SCINTIX is the first to utilize cancer itself to guide radiation delivery in real-time. https://t.co/zRbdwLSUOH

#CancerTech #CancerTreatment #MetasticCancer

[RefleXion Medical @reflexionmed]

Day 2 of ASCO is underway! Stop by our booth #2037 to hear about how BgRT may enable medical oncologists to incorporate external beam radiotherapy into their treatment algorithms for metastatic patients.

#BgRT #cancertreatment #ASCO22

[RefleXion Medical @reflexionmed]

#PressRelease: RefleXion Announces Real-World Evidence Outcomes Registry to Evaluate Treatment Impact on all Stages of Cancer https://t.co/EUjBnQj5oT

Special thanks to our partners @UTSW_RadOnc and PI @TuDDan.

#BgRT #medtech #startup #radonc

[Sean Shirvani MD MPH @SeanShirvaniMD]

Terrific to see @reflexionmed in my home state of Texas! Congratulations!!

[UTSW Radiation Oncology @UTSW_RadOnc]

Today, a team led by @TuDDan, M.D., and @BinCaiMedPhys, Ph.D., treated our first patient on the RefleXion system. The patient, part of a prospective registry, is undergoing PULSAR for liver metastases.

[Sean Shirvani MD MPH @SeanShirvaniMD]

We are headed to the Steel City! @reflexionmed

[RefleXion Medical @reflexionmed]

Another X1 leaves the building. This time we’re headed for @UPMC in Pittsburg, PA. A big thanks to our team who worked hard to make this happen.

#BgRT #CancerTreatment #RadOnc #CancerCare #MedTech

[Sean Shirvani MD MPH @SeanShirvaniMD]

Our inaugural SAB meeting for @reflexionmed was a tremendous success. Such a privilege to learn from some of the brightest minds in oncology.

[RefleXion Medical @reflexionmed]

New Scientific Advisory Board Will Help Reflexion Advance Multidisciplinary Cancer Care and Metastatic Cancer Treatment: https://t.co/WZJw1JaCgB

#CombinationTherapy #Radiotherapy #RadOnc #MedPhys #MedOnc #CancerTreatment #CancerCare #MedicalDevice #MedTech

[Sean Shirvani MD MPH @SeanShirvaniMD]

Great discussion, Terry - thanks again for joining us!

[Terry Williams @TeWilliamsMD]

@reflexionmed @COH_RadOnc @SeanShirvaniMD Great "fireside" chat! Thanks for inviting me to be a part of the discussion and allowing me to offer my perspective on BgRT at the ASTRO meeting. Certainly lots of potential for BgRT in lung cancer and other disease sites!

[Sean Shirvani MD MPH @SeanShirvaniMD]

Hope you’ll join us today if you’re in Phoenix!

[RefleXion Medical @reflexionmed]

Happening today! RefleXion Founder & CTO, Sam Mazin, PhD, is hosting a discussion on BgRT and Combination Therapy with @teWilliamsMD from @COH_RadOnc and RefleXion CMO @SeanShirvaniMD at the ASTRO Thoracic Multidisciplinary meeting.

#THORACIC21 #BgRT #cancertreatment #radonc

[Sean Shirvani MD MPH @SeanShirvaniMD]

@ChadTangMD @Prof_IanD @DrMLChua @_ShankarSiva @alantanmd @DrChoueiri @DrRanaMcKay @NRGonc @Dr_RayMak @AzadOncology @scserendipity1 @piet_ost @alison_tree @whallradonc @felixfengmd @lalaniMD @PavlosMsaouel …and it’s probably helped! For instance, we’ve probably been doing STAMPEDE-style prostate debulking in a lot of “high-risk prostate-confined dz” patients for whom bone scan simply failed to detect mets. They were oligometastatic all along and now we know they still benefited

[Sean Shirvani MD MPH @SeanShirvaniMD]

@ChadTangMD @Prof_IanD @DrMLChua @_ShankarSiva @alantanmd @DrChoueiri @DrRanaMcKay @NRGonc @Dr_RayMak @AzadOncology @scserendipity1 @piet_ost @alison_tree @whallradonc @felixfengmd @lalaniMD @PavlosMsaouel I’ve not been convinced that there is a biological bright line between stage 3 & stage 4 categories - especially since so much depends on the sensitivity of our staging tests. Suspect we’ve been treating oligometastatic dz - mis-staged as locally advanced - for decades…