maybe bc u were born in 2006 the same year they debuted😭 bigbang went on hiatus when you were 10…
just because YOU didn’t know them doesn’t mean they were nugu lmao
My urgent message to Mr @narendramodi ji. Why are you still silent on today's killing of innocent 2 babies while sleeping with her mother in midnight with rockets by Kuki militants? Manipur is not a part of India? Manipur deserves justice now. No Justice, No Rest. 😢🙏
Context of what happened today.
These aren’t fans. they’re resellers who stalk her every time she’s in Paris. I’m glad she finally stood up for herself and told them directly to leave her alone. Artists are human too. they’re not tools for people to profit from.
@ZxG_09@41m44rr1@Aishwarya1685@DipshikhaGhosh Man.. I literally applaud the confidence you two guys have on something you have no knowledge about. That's not how sampling and statistics work. Pick a book. 😭
They don’t have a problem with exposed naked waists, gyrating to ‘item’ songs, because a woman’s body is supposed to exist for a man’s arousal. Any other display is obscene and ugly to them.
This isn’t a random scientist who got lucky.
Mariano Barbacid discovered the first human oncogene in 1982. He isolated H-RAS from bladder cancer cells and proved a single point mutation could trigger cancer. That finding launched the entire field of molecular oncology.
KRAS mutations cause 90% of pancreatic cancers. For 43 years, oncologists called KRAS “undruggable” because the protein had no obvious binding pocket. Barbacid spent the last decade using genetically engineered mice to systematically test every node in the KRAS signaling pathway, looking for combinations that would work without killing the patient.
The triple therapy blocks KRAS three ways at once: the main growth signal, the escape routes through EGFR and HER2, and the stress-response backup through STAT3. Cut the engine, seal the exits, disable the emergency system. Tumors vanished in mice and didn’t return for 200+ days after treatment stopped.
Pancreatic cancer has a 13% five-year survival rate. 8% for the ductal adenocarcinoma type this therapy targets. Most patients live one year after diagnosis.
The catch: this is preclinical. Human trials are 3+ years away. One of the drugs, RMC-6236, might get approved this year, but the full triple combination has regulatory hurdles.
Still. The man who discovered human oncogenes in 1982 may have just figured out how to eliminate the cancer those genes cause. That’s a 43-year arc from first principles to potential cure. Science rarely works this clean.
Most entertainment in India (like most places in the world) was imported from the US. For decades, no one could beat the US’s domination, but somehow in the early 2000s Japan took over children’s entertainment in India
When I realised this sometime ago, I had two big questions, first of course, how did they beat US to this, and second, of all the countries in the world, how come Japanese cartoons caught on in India?
Answer was very simple, Indian TV networks needed to fill hours and hours of children’s programming every day but American kids’ content licences were very very expensive, episode counts were limited, and branding rules were tight (like you could not give advertisement slot to xyz during cartoon abc cause abc’s parent company is in competition with xyz)
The ad revenue simply wouldn’t justify the hassle
So Indian networks looked for kids entertainment from across the world, but nothing made sense, stories and cultures were too difficult to translate to an indian audience
But then they came across Japanese studios like Toei, Shin-Ei, TV Toky, etc. They sold massive episode libraries at low cost and made shows about routine activities that were very relatable for an Indian kid, say for example going to school, hanging out with friends, small everyday challenges and lessons from them, etc which made them ridiculously easy to dub and present to an Indian audience
This went on for sometime, until early 2010s when Indian studios started creating stronger IPs that caught on and closed the era of Japanese cartoons
I would like to thank everyone speaking in support of this diplomatic issue and while I’m new here & not active on X it’s because I have a very high profile Full time position working in the financial services and don’t have idle time to answer trollers! The right people get it