SeqNextGen

[SeqNextGen @SeqNextGen]

@mbeisen @timrpeterson Lior

[Nils Homer @nilshomer]

There are so many intangible benefits supporting users of your open source #Bioinformatics, but at some point you have to get paid for it. The folks asking the questions are getting paid, so why not us?

[Erik Garrison @erikgarrison]

pggb, the PanGenome Graph Builder, makes it easy to create pangenome graphs out of complete assemblies

[Lior Pachter @lpachter]

I don't get it. The @humancellatlas project is organizing a meeting in July to "continue progress towards building the first draft of the Human Cell Atlas" (see https://t.co/yGrt0CLzmY), but a first-draft human cell atlas was already published a year ago! https://t.co/kJqTUwaiYz

[Nils Homer @nilshomer]

Bioinformaticians: which one(s) do you consider yourself?

• Molecular Biology Debugger
• Technical Leader
• Thought Leader
• Expert Executor
• Pragmatic Skeptic
• Trusted Teammate

#Bioinformatics #Hiring #Genomics @fulcrumgenomics

[SeqNextGen @SeqNextGen]

@lpachter It sounds good if one can do PCR then they can do analysis too.

[SeqNextGen @SeqNextGen]

Oxford Nanopore R10.4 long-read sequencing enables the generation of near-finished bacterial genomes from pure cultures and metagenomes without short-read or reference polishing | Nature Methods https://t.co/W1v2unCxh2

[Daniel Cameron @camerongenomics]

LINX is finally published! https://t.co/HbIrpNk0Lh. A🧵on some things I learnt from working on this.

[Nature Biotechnology @NatureBiotech]

Multiplex de Bruijn graphs enable genome assembly from long, high-fidelity reads https://t.co/cEshBGavpT

[Chris Miller @chrisamiller]

bioRxiv now does not accept preprints on bioinformatics tools alone. If I have an announcement of a tool that I want to get out into the world right away, rather than in 6 months after it goes through peer review, what are some other options?

[Peter van Galen @vangalenlab]

I spent six months analyzing data that took three days to generate and I think that’s fairly representative of my experience with the dry/wetlab ratio in single cell genomics

[Glennis Logsdon @glennis_logsdon]

Excited to announce the *first* complete telomere-to-telomere assembly of a human autosome: chromosome 8! We resolved every gap in chromosome 8, including the centromere! https://t.co/EWVTr1sfbB #T2T

[PM @[email protected] @pashadag.bsky.social @pashadag]

What do Eulerian and Hamiltonian cycles have to do with genome assembly? A blog post with Mihai Pop: https://t.co/Zauwzo8Bxz

[PM @[email protected] @pashadag.bsky.social @pashadag]

Just read a cool paper (https://t.co/1vdgs1KvSD @burkhard_mstern). Main idea, as I extrapolate it: by measuring Jaccard at two values of k instead of 1, we can estimate ANI even if the sequences share a lot of non-homologous segments. Mash and similar tools fail in this case.

[Michael Schatz @mike_schatz]

Write up from the @NSF on our tomato work! https://t.co/n7d0RTOBjd

[Abdel Abdellaoui @dr_appie]

I've been developing & teaching this GWAS course since 2009, but will not be teaching it anymore. Some of the material survived since 2009, some of it only appeared recently. Feel free to use anything, this link contains slides, literature, and practicals:
https://t.co/yY1nqPkd7z

[Denis Wirtz @deniswirtz]

The President of @JohnsHopkins is an immigrant.

The Provost of @JohnsHopkins is an immigrant.

The VP for Research of @JohnsHopkins is an immigrant.

The Dean of Research of the @HopkinsMedNews is an immigrant.

[Erik Garrison @erikgarrison]

#SARSCoV2 pangenome made from 50 genomes in genbank. Top, graph viz and detail showing SNP bubbles. Middle: matrix view of genomes versus nodes in the graph. Bottom: genes versus the pangenome. CC @jervenbolleman @simonheumos @JosiahSeaman