I recently wrote a new blog for @KidneyCancer. I appreciate their willingness to let patients have an open forum for their thoughts. I encourage patients and caregivers to read this if you or a loved one is battling the “everyday” after a diagnosis. I also encourage clinicians to read this as it hopefully gives you just a little insight into what your patent is thinking while going through the routine scans after a cancer diagnosis. #kidneycancer #rcc #youngadultcancer
https://t.co/OnEgeaDrPL
A clarifying discussion from @brian_rini closing the GU session: living longer and living better, can we have both?
His synthesis across RAD-IO, RAMPART, and the decision regret work landed three points:
🔍 Chemoradiation plus durvalumab is tolerable with good short-term outcomes, but how it integrates with today's neo/adjuvant systemic regimens is still unsettled.
🔍 What CTLA-4 actually adds in adjuvant RCC remains unclear. RAMPART CTLA4/PD-L1 vs obs: DFS HR 0.65, OS HR 0.71, but a 32% bump in grade 3+ toxicity, and CheckMate 914 didn't deliver. We need RAMPART OS and non-clear cell data
🔬 Our QoL tools don't capture what patients actually live with. Patient-defined toxicity categories and regret scores belong in prospective trials, not as an afterthought.
The throughline: efficacy and toxicity have to be weighed in the same frame, and our current instruments only measure one side well.
Great discussion.
#RCC #BladderCancer #GUonc #ASCO26
#asco26 this is me: patient, caregiver, advocate, survivor. 10 years ago, my world was turned upside down when I was diagnosed with stage four kidney cancer just five days after | turned 29. I didn't know I have a rare genetic disorder called #hIrcc until it manifested as #papillarykidneycancer. Out of options after my nephrectomy, I took a leap of faith and joined a clinical trial that saved my life. I was one of two patients on PAPMET to have a complete response to #cabozantinib. I've been off treatment for six years and remain NED.
There's been some crushing losses though: my mom was diagnosed with ccRCC and lymphoma while I was going through treatment. We lost her in 2019. Countless friends who have gone before me too.
When you've been beaten down, you have a choice in your comeback. For me, that's been #patientadvocacy. What can I do to improve my fellow patients' lives? How can I help create more outcomes like mine? I didn't know how else to channel my pain, so I found my voice.
@ascocancer brings together 44,000 of the world's most dedicated oncologists, surgeons, researchers, medical professionals and patient advocates to Chicago every year to work toward improving patient lives and finding answers to cancer. I'm proud to be a Featured Voice for this year's Annual Meeting. Follow along as we get nerdy and find hope for the next five days. There's lots of beautiful moments about to take place.
https://t.co/fiFnKU1kL9
@LauraAlderMD
@DvarujoMD
@DrBarbiOnc@NazliDizman@FunchainMD
@YGaritaonandia
@Jgong15@DrSAHaddad@GIMedOnc
@oncomeraz
@SakditadMD@Rohitbanwar@lungoncdoc@RamilaShilpakar@DrSchiaffino
VISION enrolled mostly under 80. What about the 83-year-old in clinic today? Real-world data finally answer.
n=95 octogenarians on LuPSMA across DFCI, Mayo, Vanderbilt:
➡️ PSA50 57%, PSA90 23%
➡️ mPFS 7.3 mo, mOS 13.5 mo (matches VISION)
➡️ 39% hospitalized; G3+ anemia 20%
Why this matters: 💡 LuPSMA works in octogenarians and close monitoring is necessary. Congrats @PrafulRavi1 as applicable to real-world populations in the community!
#mCRPC #ProstateCA #PSMA #GUonc
Welcome home to the Artemis II crew! Honored that NASA astronauts brought iPhone to space with them. One small step for iPhone. One giant leap for space selfies. 🚀📱
Welcome home Reid, Victor, Christina, and Jeremy! 🫶
The Artemis II astronauts have splashed down at 8:07pm ET (0007 UTC April 11), bringing their historic 10-day mission around the Moon to an end.
@astro_jaz Can I just thank you for uploading these? I know I can get them via NASA as well but I’ve been dying to put some of these as my phone wallpaper lol
The Artemis II crew just named a crater “Carroll” after Reid Wiseman’s wife Carroll, who was a nurse and died May 17, 2020 at the age of 46 after a five-year battle with cancer. The two of them are pictured here with their two daughters Ellie and Katherine.
Make new friends, but keep the old.
A new photo captures the Moon's near side on the right (the side we see from Earth, identifiable by its dark splotches) and its far side on the left. The Artemis II crew are the first to see the far side with human eyes.
One last look at Earth before we reach the Moon.
This view of the Earth was captured on April 5, the fourth day of the Artemis II mission, from inside the Orion spacecraft. The four astronauts will reach their closest approach of the Moon tomorrow, April 6.