Sigel Lab

The Sigel lab focuses on the principles of metal ion-assisted folding and the structure of functional RNAs. | This group account is managed by students |

[Sigel Lab @sigel_lab]

By the way, here's the beautiful cover picture!

[Sigel Lab @sigel_lab]

There's a joint spotlight collection on Bioinorganic Chemistry between Chemical Science and Dalton Transactions - and our paper on elucidating the structure of G4 quadruplexes (https://t.co/x3AIBjZC7D) has been selected! Check out the collection here: https://t.co/KgY5bRkgfQ

[Sigel Lab @sigel_lab]

Congratulations to Matteo Lisibach for winning the Semesterpreis of the University of Zurich for his outstanding master thesis entitled "Toward multiple coordinates: Resolving the intrinsic heterogeneity of a group II intron folding and splicing process". Very well done Matteo!

[Sigel Lab @sigel_lab]

Do you want to assign solution structures of G-quadruplexes using NMR? Maybe this new approach we just published works for you. Congrats to Zhenghui and Carla for this amazing work!

https://t.co/auUCkDFe7n

[Sigel Lab @sigel_lab]

@InorgChemFront Thank you for choosing our paper on G-quadruplex DNA targeted metal complexes acting as potential anticancer drugs!

[InorgChemFront @InorgChemFront]

We are delighted to announce the Inorganic Chemistry Frontiers Outstanding Paper Awards 2014–2023！

Please join us in congratulating our winners, we hope you enjoy reading their outstanding articles as much as we did.

https://t.co/7zKWVORSFY

[Sigel Lab @sigel_lab]

A big shout out to @MuellerChem from Münster as well as Metzler-Nolte Lab from Bochum and Herris-Pawlis Lab from Aachen for putting together such a well-organized, well-caffeinated, and well-scienced conference!

[Sigel Lab @sigel_lab]

Roland and our PostDoc @LindlarNiko visited the EuroBIC17 in Münster last week. While Roland presented our work on the recently discovered theta ribozymes, Niko spoke about one of his projects from his Ph.D. in the @DaumannL Lab.

[Sigel Lab @sigel_lab]

We also would like to welcome Lennart Lindner in our group! Lennart started his Ph.D. thesis this month in the smFRET group - we wish successful experiments, good coffee and many new experiences!🙏

[Sigel Lab @sigel_lab]

The Sigel group is coming out of the summer with a few news:
Besim defended his Ph.D. thesis on illuminating the structure-function relationships in group II introns successfully! 🥳🥳Stay tuned for a publication about this!😉

[Sigel Lab @sigel_lab]

@michal_juricek @UZH_Chemistry @TilleyLab @UZH_Science @UZH_en @UZH_ch @cmszh @PatzkeGroup @JuricekLab Congratulations Tilleytubbies, you were close last year and played awesomely this year, you deserve it! See you on the courts next year, we are already looking forward to it!

[Sigel Lab @sigel_lab]

After 9 months it is time to say goodbye to our Japanese exchange student Minako - thank you for all the work you put in your NMR studies and, of course, the delicious cake!

[Sigel Lab @sigel_lab]

The chemistry booth at Science and Nature Festival powered by the Sigel lab - come join us at Campus Irchel today!

[Sigel Lab @sigel_lab]

And our application for silver is already in the making!

[Sigel Lab @sigel_lab]

We scientists have a responsibility to act against climate change. Part of that is advising and educating the public and part of it is keeping our own house in order. So, we applied and got the bronze LEAF - Laboratory Efficiency Assessment Framework - medal!

[Sigel Lab @sigel_lab]

@KKienbeck Sure will do!

[Sigel Lab @sigel_lab]

The Sigel group is starting into summer with two new members: We welcome Benjamin and Matteo for their Master projects! Benjamin is doing a specialized Master in our NMR subgroup while Matteo is doing smFRET studies. We wish few failed experiments and lots of fun in the lab!

[Sigel Lab @sigel_lab]

@KKienbeck Great work and now finally out for the world to see. Congratulations to all involved!

[Sigel Lab @sigel_lab]

We congratulate Federico Held for completing his master thesis with us. Federico introduced a heteroatom into RNA and used this to look at the BCL-2 RNA G-quadruplex. Thanks for the great time Fede!