Single Particle

Industry leader providing turn-key GPU workstations/clusters, computational tools, and tailored data processing service for the cryo-EM community and beyond.

[Single Particle @SingleParticle]

Local AI Powerhouse
Beyond #CryoEM: The SP AI Box is a universal local GPU workstation for ALL researchers. 🧬💻🛠

🚀 Now featuring OpenClaw deployment! Run an autonomous, private AI assistant directly on your local hardware.

✅ No token limit
✅ Full data privacy
✅ Local GPU-accelerated agents

Stop sending your data to the cloud. Own your AI.
🔗 https://t.co/2gACQMdw4i

#OpenSource #AI #OpenClaw #EdgeComputing #ResearchTech

[Single Particle @SingleParticle]

🚨SURPLUS SALE: Workstation Upgrade🚨

We just upgraded our servers and have some high-performance components for sale. If you need to upgrade your #cryoEM workstation, DM us or contact sales via our website! (Priority to current SP customers).

Available hardware: 💾 Samsung 3.84TB SSDs ⚡️ 32GB DDR4 memory modules 🖥️ #Nvidia 3080 Turbo 10GB GPUs ⚙️ 8-GPU servers

[Single Particle @SingleParticle]

Forwarded (still available. contact via email in the text):
https://t.co/xbPlP5fe49

[Chi-Min Ho @mimi1inh]

Learn how our hunt for the native structure of top #antimalarial target PfATP4🧂led to the discovery of PfABP, an unknown essential binding partner, out now! @natcomms 👉 https://t.co/SX5vBW1ZzT 🦠🔬❄️

A team effort by @mehsehret @cmholab & Anurag Shukla @AkhilVaidya1 #cryoEM

[Roger Castells @rcastellsg]

We’re looking for an enthusiastic postdoc to join our team. 😊

The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪

Position funded for 3 years.

Please share 🙏

Job description and details (deadline: October 11th): https://t.co/GIvf8LmbpU

[Andreas Boland @BolandLab_GE]

We want you! Join the Department of Molecular and Cellular Biology @MoCel_Geneva at the University of Geneva @unige_en @UNIGEnews @sciences_UNIGE
and become our new colleague!
Assistant (tenure-track) Professor or Associate Professor! Please RT - thanks
https://t.co/mQzmG00cxA

[Single Particle @SingleParticle]

🥪 Our partner DRTEM teams up with BESTRON for a mini lunchtime lecture at MC 2025 tomorrow!
🎁 FREE lunch — join us on Sep 1, 12:45–13:45, Room 8/9
Discover the latest:
🔬 In situ 4D-STEM detectors
📷 AI-ready CMOS cameras
🛠️ In situ holders
SingleParticle provides the GPU Workstation for Ptychography Reconstruction.
#MC2025 #4DSTEM #ElectronMicroscopy #Ptychography

[Single Particle @SingleParticle]

👋 Single Particle @ MC 2025 Karlsruhe — Booth #26b
🎁 FREE gifts + win a kids’ microscope!
Highlights:
🖥️ WhisperPro GPU (CryoEM/ET/Ptycho/AI)
🧪 Graphene Grids & VitroDrop
📷 DRTEM Cameras (TEM/4D-STEM)
#MC2025 #CryoEM #CryoET #AI #ElectronMicroscopy

[Generate:Biomedicines @generate_biomed]

We’re scaling structure as a core capability in AI-native drug design.

#TeamGenerate is searching for an Executive Director of CryoEM to lead a multidisciplinary team operating within one of the most advanced high-throughput structural biology platforms in the world. Reporting to our Chief Technology Officer, you’ll set the vision and deliver on the execution—expanding what’s possible in structural throughput and data quality. You’ll partner closely with machine learning, automation, and protein science teams to embed #cryoEM into a true design–build–test–learn loop.

This is an opportunity to shape a capability that will transform structural biology from a bottleneck into a high-speed engine for discovery—redefining how medicines are conceived, designed, and developed.

If this sounds like your next challenge, let’s talk.
https://t.co/yRjJl2oqam

[Oleksiy Kovtun @KovtunOleksiy]

Join us at MPI-NAT in Göttingen for an exciting quest of #cryoEM dissection of #membranetrafficking. Please repost.
https://t.co/0wL3JTmGDI

[ChimeraX (bsky: chimerax.ucsf.edu) @UCSFChimeraX]

ChimeraX daily builds can predict binding affinity of small molecules using Boltz 2 on your Mac, Windows or Linux computer. https://t.co/ffSIINoxUw

[Ellen Zhong @ZhongingAlong]

CryoDRGN-AI ❄️🐉🤖 is now published in @naturemethods!!! So excited to see this out and a huge congrats to @axlevy0 and team!

CryoDRGN-AI extends cryoDRGN from requiring input, fixed camera poses, to end-to-end ab initio reconstruction of biomolecules and their conformational landscapes!

Since our preprint, we have added ab initio reconstruction of cryo-ET subtomograms (@rishwanth_raghu @FeathersRyan 🙌) and several additional examples reconstructing large, messy datasets and discovery of new structures!

You can find a recent SBGrid webinar I gave about cryoDRGN-ET and cryoDRGN-AI here: https://t.co/3Td697kswV

Paper: https://t.co/z0h9UKZtR2

A few more thoughts ⬇️ (1/3)

[RMS @RoyalMicroSoc]

...And we're off! All packed and ready for #mmc2025 in Manchester next week 😀🔬🚛

We'll see you there - and if you haven't booked your ticket yet, there's still time! (Exhibition tickets are *FREE*) 👇

https://t.co/v2uCssQ4KJ

[Single Particle @SingleParticle]

🚀 New from Single Particle:
WhisperPro | 2025 – Now with 4D-STEM support
Graphene Grids – Alongside our trusted NiTi grids
VitroDrop – Portable cryo-plunger
🔗 Learn more: [https://t.co/lHTOocXSWO]
#CryoEM #CryoET #4DSTEM #GrapheneGrids #CryoPlunger

[Single Particle @SingleParticle]

🚀 Single Particle is heading to #MMC2025 with exciting new products and services!
📍 Booth #504 – Come chat with our experts!
🖥️ Computation: WhisperPro GPU Workstation (now with 4D-STEM support)
🧪 Sample Prep: Graphene Grids, VitroDrop (portable cryo-plunger)
📷 Imaging: DRTEM Huangshan Timepix & Baiyun TEM CMOS Cameras
🔗 [https://t.co/Gu0CSlKiE7]
#MMC2025, #CryoEM, #ElectronMicroscopy, #4DSTEM

[Edward T Eng @edward_eng]

Ready to use #cryoEM for structural studies but need more training to get started? Want to use your home institution's resources to make data collection ready samples?

@NCCATinfo may be in your neck of the woods to help. Find us at @DBI_Science this May.

https://t.co/ILPHbVoHhL

[Single Particle @SingleParticle]

🚀 A limited batch of RTX 4090 GPUs is now available.
Looking for a high-performance, cost-effective workstation?
📩 Reach out to customize your ideal setup:
👉 https://t.co/QGGbkp9pQX
#GPUWorkstation #RTX4090 #StructuralBiology