Sisi Chen

Scientist @ Caltech. Ph.D. Director of @SPEC_Caltech. Computational biology, big data, immunology, and stem cells. | Writer | Artist | She/her

[Sisi Chen @sisichen]

Very excited to share that our paper was just published today in PNAS! https://t.co/uPuEHK9yfg

[Sisi Chen @sisichen]

@naturemethods @Allan_HPool Congrats on the new paper @Allan_HPool !!!

[Sisi Chen @sisichen]

@cmcginnis92 Thanks so much Chris!! So much kudos to Jialong for developing the spin network modeling framework and handling massive amounts of data with such ease.

[Sisi Chen @sisichen]

@LADWP Power just out in Mt Washington 90055

[Sisi Chen @sisichen]

@ENSAlerts Why not ask employers and businesses to turn up thermostats a few degrees, and reduce air conditioning at night when people are not working? Have seen a lot of calls for individuals to tackle the problem but not employers.

[SPEC Caltech @SPEC_Caltech]

maximally informative. Her method is very resource efficient, allowing her to compute >1M cells on a fairly typical AWS instance. https://t.co/1elUgnAldV

[Sisi Chen @sisichen]

Missing genes due to introns and poor 3’ annotations is such a big problem across so many single-cell datasets and @Allan_HPool’s method offers a rational, systematic way to address it. So happy to see this work out now!

[Allan-Hermann Pool @Allan_HPool]

First Pool Lab pre-print: https://t.co/e3vDzRXPrr. We resolve a major pain with 3’ single-cell RNA-sequencing (10x Genomics etc.) – missing gene expression data from thousands of genes. This stems from suboptimal reference transcriptomes and can easily be recovered. T below: 1/12

[Sisi Chen @sisichen]

@claudiaraudia @UWBiochemistry Congrats Claudia!! UW is so lucky to have you!

[Sisi Chen @sisichen]

@DeborahNetburn Hi Deborah! So fun meeting you in the neighborhood this morning!

[Sisi Chen @sisichen]

@WallaceUcsf @frazierarchive I’m glad it’s gotten so much love over the years! I feel like I should make you a fresh one soon!

[Sisi Chen @sisichen]

@PracheeAC I guess the question is whether you read it or skimmed through selectively for information you’re interested in..

[Sisi Chen @sisichen]

Once you hit your mid-30s, you realize that the most popular social media platform is now holiday cards.

[SPEC Caltech @SPEC_Caltech]

We are hiring!! Looking to hire a research technician to execute a focused project on exploring human cell surface proteins on the human immune system using single-cell RNA-seq. https://t.co/R0ZaJXNjs4

[Sisi Chen @sisichen]

@jessicadefino_ @Slate Btw, love the detail on skin microbes producing beneficial molecules for skin health. That's cool!

[Sisi Chen @sisichen]

@jessicadefino_ @Slate However! I do think some products can be helpful. I was a beauty product minimalist for most of my life, but now swear by a few things: a ceramide face cream. and vitamin C and niacinimide to help with fading age spots. and sunscreen.

[Sisi Chen @sisichen]

@jessicadefino_ @Slate Totally, I'm really wary of most products with intense active ingredients (like retinoids) since they can cause more damage.

[Sisi Chen @sisichen]

@jessicadefino_ @Slate Ah I see! Steroid withdrawal is insane. I have a friend who got steroid addicted due to bad eczema and his whole body erupted in rashes that didn't resolve for about two years.

[Sisi Chen @sisichen]

@jessicadefino_ @Slate Do you think need for beauty products is just highly individual? Perhaps you were simply blessed with tremendously high-functioning skin

[Sisi Chen @sisichen]

@jessicadefino_ @Slate Congrats on finally getting it published! The article mostly resonates... except on the necessity of moisturizers. My skin is incredibly dry in the climate I live in (socal). Even when I don't use soap, I have to use ceramide cream or else i get dry flaky patches....

[Sisi Chen @sisichen]

The leading edge is an incredible group of insanely talented scientists. I can't recommend it more.

[Sisi Chen @sisichen]

So sad to hear Arthur Mattuck has passed. I took more classes from him than any other prof. I'll never forget how he roasted us to make us pay more attention. "Grading your homework was like prospecting for gold, or even silver.... or maybe just lead." https://t.co/p2mcIKvW1o