Siyu Chen

Graduate student at @NorthwesternU @YuanHeJHU
HHMI @JCChildsFund fellow at @UCSD @TheVillaLab
#CryoEM #TeamTomo

[Fabian @EisFabian]

SPACEtomo v1.2 is online! https://t.co/3GO6qP9Z07

- Improved GUIs for lamella detection, target selection and CLEM registration make it the best target selection workflow for PACEtomo on any kind of lamella sample.
- Easier installation and configuration
Any feedback welcome!

[Siyu Chen @SiyuChen91]

Huge thanks to our best LRRK2 team member @TheVillaLab and the @aleschziner group with in the @ASAP_Research team who I worked with all the time!

[Siyu Chen @SiyuChen91]

Check out our new preprint revealing an unidentified LRRK2 oligomerization state on microtubules: https://t.co/irAg2zOl3M
Satisfying first attempt working on the cryo-ET #TeamTomo data led to a nice piece of finding😌 More to come on this versatile and intriguing protein!

[Siyu Chen @SiyuChen91]

Huge honor to receive this reward! Many thanks to @thermosciEMSpec! This means a lot to me.

[Microscopy & Spectroscopy @thermosciEMSpec]

Please give a big round of applause to @SiyuChen91, @thermofisher's 2023 #CryoEM Grant Program Silver Winner!

Siyu is a postdoctoral fellow at @TheVillaLab at @UCSanDiego / @HHMINEWS.

Learn about his research proposal here: https://t.co/kdbz3Jrukd

[Anna Talyzina @anna_talyzina]

And now the peer-reviewed version is online! https://t.co/T1d0b2kIO1

[Siyu Chen @SiyuChen91]

Truly honored and excited to join the cohort of 2023 @JCChildsFund fellows. Many thanks to everyone in @TheVillaLab and @YuanHe_NWU. Nothing would be possible without you all. https://t.co/4x2lROmuzh

[Siyu Chen @SiyuChen91]

Also don't forget to check out this complementary study from @AmandaChaplin10 and colleagues:
https://t.co/FcI3MDUCCj

[Siyu Chen @SiyuChen91]

Glad to present the second part of my thesis project done with @YuanHe_NWU! Using #CryoEM, we visualized how DNA-PKcs adopt different intermediate states during NHEJ #DNArepair and how a scaffolding factor, PAXX, stabilizes the complexes. Please check https://t.co/MIvPbin28j

[Siyu Chen @SiyuChen91]

Many thanks to everyone in the He lab (miss you guys so much!!) and as always, our wonderful collaborators Susan Lees-Miller and Alan Tomkinson!

[Siyu Chen @SiyuChen91]

@avibpatel_ @YuanHe_NWU @NatureComms Wooo congratulations!!

[Elizabeth Villa @TheVillaLab]

#teamtomo tweeps, @lindsey__young wrote a tell-all. Clutch your pearls and get ready to plan your project! (Or explain to your structure or cell bio friends how to think about it) Including epic illustration w/@DoroteaArt. Pls RT!
https://t.co/yOCzGAPsq9

[Tom Marlovits @MarlovitsLab]

Resolving the AAA+ ATPase Puzzle in Slow Motion.

Cutting-edge cryoEM, time-resolved studies and slower burning fuels. Big thanks to the heroes of the M-team; esp. @JirkaWald @DirkFahrenkamp. Enjoy! (https://t.co/6cOvGOBR8O)

[Denis Wirtz @deniswirtz]

Rather stunning, but here we are: we have identified 552 funding opportunities that are specially targeted to early-career faculty.

We list subject, deadline, amount, link for each opportunity.

Download here: https://t.co/RGXGrd7r5F

[cryoEM Papers @cryoEM_Papers]

Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids https://t.co/abLg1BKkEb

[cryoEM Papers @cryoEM_Papers]

In situ architecture of the ciliary base reveals the stepwise assembly of IFT trains https://t.co/O0El5c8y74

[cryoEM Papers @cryoEM_Papers]

In situ Alphavirus Assembly and Budding Mechanism Revealed by Cellular CryoET https://t.co/B1pMZpIF5K

[Anthony Schuller @aschuller17]

Excited to share my work from @SchwartzLabMIT in @MITBiology titled “The cellular environment shapes the nuclear pore complex architecture” online today in @Nature! https://t.co/UhlHUSn8Z1 #cryo-EM #cryo-ET #TeamTomo #NPC 1/n

[cryoEM Papers @cryoEM_Papers]

Whole-cell organelle segmentation in volume electron microscopy https://t.co/GeUhXllSyY

[@IAmSciComm - On a Break! @iamscicomm]

A thread on understanding the importance of 'complementary colors' in science figures 🎨👇🏼
(tl;dr, it will enhance color harmony, make your data 'pop', highlight antagonistic reactions, and keep your images color-blind accessible)

[HHMI @hhmi_science]

HHMI News: We are proud to announce our 33 new #HHMIInvestigators. These individuals have the potential to make transformative discoveries over time and we look forward to seeing where their ideas lead them. https://t.co/HziK6G5Q6y